Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Bjarne, Bogen"'
Autor:
Daniëla Maria Hinke, Ane Marie Anderson, Kirankumar Katta, Marlene Fyrstenberg Laursen, Demo Yemane Tesfaye, Ina Charlotta Werninghaus, Davide Angeletti, Gunnveig Grødeland, Bjarne Bogen, Ranveig Braathen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Conserved epitopes shared between virus subtypes are often subdominant, making it difficult to induce broadly reactive antibodies by immunization. Here, we generate a plasmid DNA mix vaccine that encodes protein heterodimers with sixteen dif
Externí odkaz:
https://doaj.org/article/457738f6253942d9a9c305bb32c0e1ce
Autor:
Pegah Abdollahi, Bjarne Bogen, Marita Westhrin, Jana Blazevski, Ana Textor, Ramakrishna Prabhu Gopalakrishnan, Linda Thuy Ngo, Peter Olaf Hofgaard, Julia Heinzelbecker, Sonja Bobic, Even Fossum, Heidi Cecilie Larsen Spång, Ranveig Braathen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Multiple myeloma (MM) cancers originate from plasma cells that have passed through the germinal center reaction where somatic hypermutation of Ig V regions takes place. Myeloma protein V regions often express many mutations and are thus a
Externí odkaz:
https://doaj.org/article/c6d7905d7d25416ab5b08b84cc92af18
Autor:
Cassandra Métivier, Patricia Le Saëc, Joëlle Gaschet, Catherine Chauvet, Séverine Marionneau-Lambot, Peter O. Hofgaard, Bjarne Bogen, Julie Pineau, Nathalie Le Bris, Raphaël Tripier, Cyrille Alliot, Férid Haddad, Michel Chérel, Nicolas Chouin, Alain Faivre-Chauvet, Latifa Rbah-Vidal
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1817 (2023)
Although the concept of theranostics is neither new nor exclusive to nuclear medicine, it is a particularly promising approach for the future of nuclear oncology. This approach is based on the use of molecules targeting specific biomarkers in the tum
Externí odkaz:
https://doaj.org/article/e9ef0bbdb1f6481592abe4acf5b206e8
Autor:
Raquel Lopes, Joana Caetano, Filipa Barahona, Carolina Pestana, Bruna Velosa Ferreira, Diana Lourenço, Ana C. Queirós, Carlos Bilreiro, Noam Shemesh, Hans Christian Beck, Ana Sofia Carvalho, Rune Matthiesen, Bjarne Bogen, Bruno Costa-Silva, Karine Serre, Emilie Arnault Carneiro, Cristina João
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Multiple myeloma (MM), the third most frequent hematological cancer worldwide, is characterized by the proliferation of neoplastic plasma cells in the bone marrow (BM). One of the hallmarks of MM is a permissive BM microenvironment. Increasing eviden
Externí odkaz:
https://doaj.org/article/d196af56064e4460b728d59ff0ce7d5d
Autor:
Ranveig Braathen, Heidi Cecilie Larsen Spång, Daniëla Maria Hinke, Jana Blazevski, Sonja Bobic, Even Fossum, Bjarne Bogen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 378-392 (2020)
Immunogenicity of DNA vaccines can be increased by constructing the DNA in such a way that it encodes secreted homodimeric fusion proteins that target antigen-presenting cells (APCs). In this study, we have developed novel APC-targeting vaccine molec
Externí odkaz:
https://doaj.org/article/88cb418c2a3343fea198aa5119fa10e5
Autor:
Selma Bekri, Reunet Rodney-Sandy, Diana Gruenstein, Anna Mei, Bjarne Bogen, John Castle, Daniel Levey, Hearn Jay Cho
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background Cancer-associated neoantigens (neoAg) derived from tumor genomic sequencing and predictive algorithms for mutated peptides are a promising basis for therapeutic vaccines under investigation. Although these are generally designed to bind ma
Externí odkaz:
https://doaj.org/article/f3e47cf491c84b1d9989d647255dd0da
Autor:
Demo Yemane Tesfaye, Sonja Bobic, Anna Lysén, Peter Csaba Huszthy, Arnar Gudjonsson, Ranveig Braathen, Bjarne Bogen, Even Fossum
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Targeting antigen to conventional dendritic cells (cDCs) can improve antigen-specific immune responses and additionally be used to influence the polarization of the immune responses. However, the mechanisms by which this is achieved are less clear. T
Externí odkaz:
https://doaj.org/article/5453121082fc42ef863447fc1290adc0
Autor:
Tor Kristian Andersen, Johanna Bodin, Fredrik Oftung, Bjarne Bogen, Siri Mjaaland, Gunnveig Grødeland
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The 2009 “swine flu” pandemic outbreak demonstrated the limiting capacity for egg-based vaccines with respect to global vaccine supply within a timely fashion. New vaccine platforms that efficiently can quench pandemic influenza emergences are ur
Externí odkaz:
https://doaj.org/article/100c9939bdc2493b9d71e4b39ce09c98
Autor:
Louise Bjerkan, Ganesh Ram R. Visweswaran, Arnar Gudjonsson, Geneviève M. Labbé, Doris Quinkert, David J. Pattinson, Heidi C. L. Spång, Simon J. Draper, Bjarne Bogen, Ranveig Braathen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Targeted delivery of antigen to antigen presenting cells (APCs) is an efficient way to induce robust antigen-specific immune responses. Here, we present a novel DNA vaccine that targets the Plasmodium falciparum reticulocyte-binding protein homolog 5
Externí odkaz:
https://doaj.org/article/aa3e7e36c41d42eba77b84480a104e26
Autor:
Peter Szodoray, Tor Kristian Andersen, Julia Heinzelbecker, John F. Imbery, Peter C. Huszthy, Stephanie M. Stanford, Bjarne Bogen, Ole B. Landsverk, Nunzio Bottini, Anders Tveita, Ludvig A. Munthe, Britt Nakken
Publikováno v:
Cell Reports, Vol 36, Iss 6, Pp 109525- (2021)
Summary: Humoral immunity relies on the efficient differentiation of memory B cells (MBCs) into antibody-secreting cells (ASCs). T helper (Th) signals upregulate B cell receptor (BCR) signaling by potentiating Src family kinases through increasing CD
Externí odkaz:
https://doaj.org/article/eb782f741c90461f80cc29c4bb22a13b