Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Bjørn-Eivind Kirsebom"'
Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease
Autor:
Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, José Contador, Jordan E. Tanley, Per Selnes, Berglind Gísladóttir, Lene Pålhaugen, Mathilde Suhr Hemminghyth, Jonas Jarholm, Ragnhild Skogseth, Geir Bråthen, Gøril Grøndtvedt, Atle Bjørnerud, Sandra Tecelao, Knut Waterloo, Dag Aarsland, Aida Fernández-Lebrero, Greta García-Escobar, Irene Navalpotro-Gómez, Michael Turton, Agnes Hesthamar, Przemyslaw R. Kac, Johanna Nilsson, Jose Luchsinger, Kathleen M. Hayden, Peter Harrison, Albert Puig-Pijoan, Henrik Zetterberg, Timothy M. Hughes, Marc Suárez-Calvet, Thomas K. Karikari, Tormod Fladby, Kaj Blennow
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). In blood, phosphorylated tau (p-tau) associates with Aβ patho
Externí odkaz:
https://doaj.org/article/b027901016fa4e8ba7386d92b8d8e45e
Autor:
Kaja Nordengen, Bjørn-Eivind Kirsebom, Grit Richter, Lene Pålhaugen, Berglind Gísladóttir, Nikias Siafarikas, Arne Nakling, Arvid Rongve, Geir Bråthen, Gøril Rolfseng Grøntvedt, Fernando Gonzalez, Knut Waterloo, Kulbhushan Sharma, Thomas Karikari, Eleonora M. Vromen, Betty M. Tijms, Pieter J. Visser, Per Selnes, Milicia G. Kramberger, Bengt Winblad, Kaj Blennow, Tormod Fladby
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Background Brain innate immune activation is associated with Alzheimer’s disease (AD), but degrees of activation may vary between disease stages. Thus, brain innate immune activation must be assessed in longitudinal clinical studies that i
Externí odkaz:
https://doaj.org/article/e8a9047557934ffca73d41a8657fb122
Autor:
Cecilia Magdalena Eriksson, Bjørn-Eivind Kirsebom, Ragna Espenes, Nikias Siafarikas, Knut Waterloo, Arvid Rongve, Per Selnes, Dag Aarsland, Tormod Fladby, Erik Hessen
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra (2024)
ABSTRACT INTRODUCTION: Depressive symptoms are associated with Alzheimer’s disease (AD), but their neurobiological and neuropsychological correlates remain poorly understood. We investigate if depressive symptoms are associated with amyloid (Aβ) p
Externí odkaz:
https://doaj.org/article/39b4331569af4ec3b84f80bb3883ae8d
Autor:
Mostafa Mehdipour Ghazi, Per Selnes, Santiago Timón-Reina, Sandra Tecelão, Silvia Ingala, Atle Bjørnerud, Bjørn-Eivind Kirsebom, Tormod Fladby, Mads Nielsen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionEfforts to develop cost-effective approaches for detecting amyloid pathology in Alzheimer's disease (AD) have gained significant momentum with a focus on biomarker classification. Recent research has explored non-invasive and readily acce
Externí odkaz:
https://doaj.org/article/5aa00918684b4d0ab048ec6a1d6f0aae
Autor:
Julia K. Gundersen, Fernando Gonzalez-Ortiz, Thomas Karikari, Bjørn-Eivind Kirsebom, Katrin Mertes, Henrik Zetterberg, Hlin Kvartsberg, Ole Morten Rønning, Berglind Gísladóttir, Kaj Blennow, Tormod Fladby
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100291- (2024)
Introduction: Diagnosis of acute ischemic stroke (AIS) as based on clinical examination and neuroimaging has limitations in determining subgroup aetiology and subsequent long-term motor and cognitive impairment. Identification of high-risk patients e
Externí odkaz:
https://doaj.org/article/91cbf6f4238f40b4a713303257d1f3a9
Autor:
Lene Pålhaugen, Berglind Gísladóttir, Jonas Alexander Jarholm, Bjørn-Eivind Kirsebom, Per Selnes, Tormod Fladby
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100304- (2024)
Introduction: Angiogenic mediators like placental growth factor (PlGF) and vascular endothelial growth factors (VEFG-C and VEFG-A) in cerebrospinal fluid (CSF) are suggested markers of cerebral small vessel disease (SVD). SVD is a cause of vascular c
Externí odkaz:
https://doaj.org/article/5010ea89e7b24359981c91198ae1e63e
Autor:
Klaus Thanke Aspli, Jan O. Aaseth, Trygve Holmøy, Kaj Blennow, Henrik Zetterberg, Bjørn-Eivind Kirsebom, Tormod Fladby, Per Selnes
Publikováno v:
Brain Sciences, Vol 13, Iss 11, p 1511 (2023)
Skogholt’s disease is a rare neurological disorder that is only observed in a small Norwegian kindred. It typically manifests in adulthood with uncharacteristic neurological symptoms from both the peripheral and central nervous systems. The etiolog
Externí odkaz:
https://doaj.org/article/008136d6590244e5aa5d5eafebecfc93
Autor:
Santiago Timón-Reina, Mariano Rincón, Rafael Martínez-Tomás, Bjørn-Eivind Kirsebom, Tormod Fladby
Publikováno v:
Applied Sciences, Vol 13, Iss 18, p 10497 (2023)
Dementia disease research encompasses diverse data modalities, including advanced imaging, deep phenotyping, and multi-omics analysis. However, integrating these disparate data sources has historically posed a significant challenge, obstructing the u
Externí odkaz:
https://doaj.org/article/57bde630e8a74414a3649cb06202e1f4
Cerebrospinal fluid markers for synaptic function and Alzheimer type changes in late life depression
Autor:
Nikias Siafarikas, Bjørn-Eivind Kirsebom, Deepak P. Srivastava, Cecilia M. Eriksson, Eirik Auning, Erik Hessen, Geir Selbaek, Kaj Blennow, Dag Aarsland, Tormod Fladby
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract To explore markers for synaptic function and Alzheimer disease (AD) pathology in late life depression (LLD), predementia AD and normal controls (NC). A cross-sectional study to compare cerebrospinal fluid (CSF) levels of neurogranin (Ng), Be
Externí odkaz:
https://doaj.org/article/ceac521b63374c52b81ca8b89a686a9d
Autor:
Nikias Siafarikas, Bjørn-Eivind Kirsebom, Deepak P. Srivastava, Cecilia M. Eriksson, Eirik Auning, Erik Hessen, Geir Selbaek, Kaj Blennow, Dag Aarsland, Tormod Fladby
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/ab59e775595f429e8716a9bd98126336