Zobrazeno 1 - 10
of 311
pro vyhledávání: '"Bjørn Naume"'
Autor:
Abhibhav Sharma, Julia Debik, Bjørn Naume, Hege Oma Ohnstad, Oslo Breast Cancer Consortium (OSBREAC), Tone F. Bathen, Guro F. Giskeødegård
Publikováno v:
Oncogenesis, Vol 13, Iss 1, Pp 1-13 (2024)
Abstract Breast cancer (BC) is a leading cause of cancer-related death worldwide. The diverse nature and heterogeneous biology of BC pose challenges for survival prediction, as patients with similar diagnoses often respond differently to treatment. C
Externí odkaz:
https://doaj.org/article/11d3e2fb5e8e44b79e82cb05230e5944
Autor:
Sudhir Kumar Chauhan, Claire Dunn, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Gjertrud Skorstad, Adam Sike, Bjørnar Gilje, Sunil Xavier Raj, Kanutte Huse, Bjørn Naume, Jon Amund Kyte
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Immunotherapies blocking the PD-1/PD-L1 checkpoint show some efficacy in metastatic breast cancer (mBC) but are often hindered by immunosuppressive mechanisms. Understanding these mechanisms is crucial for personalized treatments, with perip
Externí odkaz:
https://doaj.org/article/21138a5be7fa4ef6868ac4e8d5f2a5bf
Autor:
Wanja Kildal, Karolina Cyll, Joakim Kalsnes, Rakibul Islam, Frida M. Julbø, Manohar Pradhan, Elin Ersvær, Neil Shepherd, Ljiljana Vlatkovic, Xavier Tekpli, Øystein Garred, Gunnar B. Kristensen, Hanne A. Askautrud, Tarjei S. Hveem, Håvard E. Danielsen, Tone F. Bathen, Elin Borgen, Anne-Lise Børresen-Dale, Olav Engebråten, Britt Fritzman, Olaf Johan Hartman-Johnsen, Jürgen Geisler, Gry Aarum Geitvik, Solveig Hofvind, Rolf Kåresen, Anita Langerød, Ole Christian Lingjærde, Gunhild M. Mælandsmo, Bjørn Naume, Hege G. Russnes, Kristine Kleivi Sahlberg, Torill Sauer, Helle Kristine Skjerven, Ellen Schlichting, Therese Sørlie
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e32529- (2024)
We aimed to develop deep learning (DL) models to detect protein expression in immunohistochemically (IHC) stained tissue-sections, and to compare their accuracy and performance with manually scored clinically relevant proteins in common cancer types.
Externí odkaz:
https://doaj.org/article/e0dc5fe8cfec49769db7555ff4402d86
Autor:
Ragnhild Sørum Falk, Bjornar Gilje, Andrea Gombos, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Claire Quaghebeur, Beate Boge, Randi R. Mathiesen, Lars Julsrud, Øystein Garred, Hege G. Russnes, Ragnhild Reehorst Lereim, Sudhir Kumar Chauhan, Ole Christian Lingjærde, Claire Dunn, Bjørn Naume, Jon Amund Kyte
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background Immune checkpoint inhibitors have shown minimal clinical activity in hormone receptor-positive metastatic breast cancer (HR+mBC). Doxorubicin and low-dose cyclophosphamide are reported to induce immune responses and counter regulatory T ce
Externí odkaz:
https://doaj.org/article/e9ba64ad31414caeaea3d72626619d91
Autor:
Johan Staaf, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal, Siker Kimbung, Ingrid Hedenfalk, Tonje Lien, Therese Sørlie, Bjørn Naume, Hege Russnes, Rachel Marcone, Ayyakkannu Ayyanan, Cathrin Brisken, Rebecka R. Malterling, Bengt Asking, Helena Olofsson, Henrik Lindman, Pär-Ola Bendahl, Anna Ehinger, Christer Larsson, Niklas Loman, Lisa Rydén, Martin Malmberg, Åke Borg, Johan Vallon-Christersson
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-17 (2022)
Abstract Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, subtypes, and risk of recurrence (
Externí odkaz:
https://doaj.org/article/d2e56c524d0b4a448d746df4499518bd
Autor:
Yngvar Nilssen, Odd Terje Brustugun, Morten Tandberg Eriksen, Marianne G. Guren, Erik Skaaheim Haug, Bjørn Naume, Ellen Schlichting, Bjørn Møller
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Cancer patient pathways (CPPs) were implemented in Norway to reduce unnecessary waiting times, regional variations, and to increase the predictability of cancer care for the patients. This study aimed to determine if 70% of cancer
Externí odkaz:
https://doaj.org/article/f1e88728779a43d0803e29d8f28fd44c
Autor:
Thomas Helland, Bjørn Naume, Steinar Hustad, Ersilia Bifulco, Jan Terje Kvaløy, Anna Barbro Sætersdal, Marit Synnestvedt, Tone Hoel Lende, Bjørnar Gilje, Ingvil Mjaaland, Kjetil Weyde, Egil Støre Blix, Gro Wiedswang, Elin Borgen, Daniel Louis Hertz, Emiel Adrianus Maria Janssen, Gunnar Mellgren, Håvard Søiland
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 957-967 (2021)
Low steady‐state levels of active tamoxifen metabolites have been associated with inferior treatment outcomes. In this retrospective analysis of 406 estrogen receptor‐positive breast cancer (BC) patients receiving adjuvant tamoxifen as initial tr
Externí odkaz:
https://doaj.org/article/162b341b32bb451fafcf55ad582ca776
Autor:
Kristi Krüger, Laxmi Silwal-Pandit, Elisabeth Wik, Oddbjørn Straume, Ingunn M. Stefansson, Elin Borgen, Øystein Garred, Bjørn Naume, Olav Engebraaten, Lars A. Akslen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract A subset of breast cancer patients benefits from preoperative bevacizumab and chemotherapy, but validated predictive biomarkers are lacking. Here, we aimed to evaluate tissue-based angiogenesis markers for potential predictive value regardin
Externí odkaz:
https://doaj.org/article/c8a2b3892eea4e2a921d64ce837fe2d4
Autor:
Harald Hugenschmidt, Knut Jørgen Labori, Cathrine Brunborg, Caroline Sophie Verbeke, Lars Thomas Seeberg, Cecilie Bendigtsen Schirmer, Anne Renolen, Elin Borgen, Bjørn Naume, Gro Wiedswang
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Pancreatic and periampullary carcinoma are aggressive tumours where preoperative assessment is challenging. Disseminated tumour cells (DTC) in the bone marrow (BM) are associated with impaired prognosis in a variety of epithelial
Externí odkaz:
https://doaj.org/article/ef0ed3fa93b44b7a976b0c58e4e797b3
Autor:
Yngvar Nilssen, Odd Terje Brustugun, Morten Tandberg Eriksen, Erik Skaaheim Haug, Bjørn Naume, Bjørn Møller
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Cancer patient pathways (CPPs) were implemented in 2015 to reduce waiting time, regional variation in waiting time, and to increase the predictability of cancer care for the patients. The aims of this study were to see if the nati
Externí odkaz:
https://doaj.org/article/2a3b37da840644dab4f585cacbab58d8