Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles:A Mendelian randomization analysis

Autor: Helgadottir, Anna, Thorleifsson, Gudmar, Snaebjarnarson, Audunn, Stefansdottir, Lilja, Sveinbjornsson, Gardar, Tragante, Vinicius, Björnsson, Eyþór, Steinthorsdottir, Valgerdur, Gretarsdottir, Solveig, Helgason, Hannes, Saemundsdottir, Jona, Olafsson, Isleifur, Thune, Jens Jakob, Axelsson Raja, Anna, Ghouse, Jonas, Olesen, Morten Salling, Christensen, Alex, Jacobsen, Rikke Louise, Dowsett, Joseph, Bruun, Mie Topholm, Nielsen, Kaspar, Knowlton, Kirk, Nadauld, Lincoln, Benediktsson, Rafn, Erikstrup, Christian, Pedersen, Ole B., Banasik, Karina, Brunak, Søren, Bundgaard, Henning, Ostrowski, Sisse R., Sulem, Patrick, Arnar, David O., Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Stefansson, Kari, Holm, Hilma, Nyegaard, Mette

Publikováno v: Helgadottir, A, Thorleifsson, G, Snaebjarnarson, A, Stefansdottir, L, Sveinbjornsson, G, Tragante, V, Björnsson, E, Steinthorsdottir, V, Gretarsdottir, S, Helgason, H, Saemundsdottir, J, Olafsson, I, Thune, J J, Axelsson Raja, A, Ghouse, J, Olesen, M S, Christensen, A, Jacobsen, R L, Dowsett, J, Bruun, M T, Nielsen, K, Knowlton, K, Nadauld, L, Benediktsson, R, Erikstrup, C, Pedersen, O B, Banasik, K, Brunak, S, Bundgaard, H, Ostrowski, S R, Sulem, P, Arnar, D O, Thorgeirsson, G, Thorsteinsdottir, U, Gudbjartsson, D F, Stefansson, K, Holm, H & DBDS Genomic Consortium 2022, ' Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles : A Mendelian randomization analysis ', European Journal of Preventive Cardiology, vol. 29, no. 18, pp. 2374-2385 . https://doi.org/10.1093/eurjpc/zwac219
Helgadottir, A, Thorleifsson, G, Snaebjarnarson, A, Stefansdottir, L, Sveinbjornsson, G, Tragante, V, Björnsson, E, Steinthorsdottir, V, Gretarsdottir, S, Helgason, H, Saemundsdottir, J, Olafsson, I, Thune, J J, Axelsson Raja, A, Ghouse, J, Olesen, M S, Christensen, A, Jacobsen, R L, Dowsett, J, Bruun, M T, Nielsen, K, Knowlton, K, Nadauld, L, Benediktsson, R, Erikstrup, C, Pedersen, O B, Banasik, K, Brunak, S, DBDS Genomic Consortium, Bundgaard, H, Ostrowski, S R, Sulem, P, Arnar, D O, Thorgeirsson, G, Thorsteinsdottir, U, Gudbjartsson, D F, Stefansson, K, Holm, H & Nyegaard, M 2022, ' Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles-A Mendelian randomization analysis ', European Journal of Preventive Cardiology, vol. 29, no. 18, zwac219, pp. 2374-2385 . https://doi.org/10.1093/eurjpc/zwac219
Helgadottir, A, Thorleifsson, G, Snaebjarnarson, A, Stefansdottir, L, Sveinbjornsson, G, Tragante, V, Björnsson, E, Steinthorsdottir, V, Gretarsdottir, S, Helgason, H, Saemundsdottir, J, Olafsson, I, Thune, J J, Axelsson Raja, A, Ghouse, J, Olesen, M S, Christensen, A, Jacobsen, R L, Dowsett, J, Bruun, M T, Nielsen, K, Knowlton, K, Nadauld, L, Benediktsson, R, Erikstrup, C, Pedersen, O B, Banasik, K, Brunak, S, Bundgaard, H, Ostrowski, S R, Sulem, P, Arnar, D O, Thorgeirsson, G, Thorsteinsdottir, U, Gudbjartsson, D F, Stefansson, K, Holm, H & DBDS Genomic Consortium 2022, ' Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles-A Mendelian randomization analysis ', European Journal of Preventive Cardiology, vol. 29, no. 18, pp. 2374–2385 . https://doi.org/10.1093/eurjpc/zwac219

Background and aims:The causal contribution of apolipoprotein B (apoB) particles to coronary artery disease (CAD) is established. We examined whether this atherogenic contribution is better reflected by non-high-density lipoprotein cholesterol (non-H

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https://pure.au.dk/portal/da/publications/cholesterol-not-particle-concentration-mediates-the-atherogenic-risk-conferred-by-apolipoprotein-b-particles(6ba7ddb1-b4a5-423c-9f98-107bd8082294).html

Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles: a Mendelian randomization analysis

Autor: Helgadottir, Anna, Thorleifsson, Gudmar, Snaebjarnarson, Audunn, Stefansdottir, Lilja, Sveinbjornsson, Gardar, Tragante, Vinicius, Björnsson, Eyþór, Steinthorsdottir, Valgerdur, Gretarsdottir, Solveig, Helgason, Hannes, Saemundsdottir, Jona, Olafsson, Isleifur, Thune, Jens Jakob, Raja, Anna Axelsson, Ghouse, Jonas, Olesen, Morten Salling, Christensen, Alex, Jacobsen, Rikke Louise, Dowsett, Joseph, Bruun, Mie Topholm, Nielsen, Kaspar, Knowlton, Kirk, Nadauld, Lincoln, Benediktsson, Rafn, Erikstrup, Christian, Pedersen, Ole B, Banasik, Karina, Brunak, Søren, Bundgaard, Henning, Ostrowski, Sisse R, Sulem, Patrick, Arnar, David O, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Stefansson, Kari, Holm, Hilma

Publikováno v: European Journal of Preventive Cardiology; December 2022, Vol. 29 Issue: 18 p2374-2385, 12p