Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Björn-Philipp Kloke"'
Autor:
Silke Schüle, Björn-Philipp Kloke, Julia K Kaiser, Sabine Heidmeier, Sylvia Panitz, Nina Wolfrum, Klaus Cichutek, Matthias Schweizer
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7098 (2009)
BACKGROUND: Human primary monocytes are refractory to infection with the human immunodeficiency virus 1 (HIV-1) or transduction with HIV-1-derived vectors. In contrast, efficient single round transduction of monocytes is mediated by vectors derived f
Externí odkaz:
https://doaj.org/article/6a8cff5771404e6fb4f2cc5ef022333d
Autor:
Jochen Utikal, Isabel Vogler, Özlem Türeci, Tana Omokoko, Christoph Höller, Matthias Miller, Björn-Philipp Kloke, Inga Ortseifer, Sebastian Attig, Goran Martic, Barbara Schrörs, Andrea Breitkreuz, Christoph Huber, Janina Buck, Valesca Bukur, Alexander Hohberger, Andreas Kuhn, Anna Paruzynski, Martina Zillgen, Meike Witt, Sandra Heesch, Jan Diekmann, Stefanie Bolte, Evelyna Derhovanessian, Christoffer Gebhardt, Ulrich Luxemburger, Alexandra-Kemmer Brück, Petra Simon, Arbel D. Tadmor, Patrick Sorn, Stephan Grabbe, Felicitas Müller, Sebastian Kreiter, Martin Suchan, David Langer, Mathias Vormehr, Christian Albrecht, Mustafa Diken, Eva Godehardt, Claudia Tolliver, Romina Nemecek, Martin Löwer, Katharina H Schreeb, Barbara Kasemann, Richard Rae, Carmen Loquai, Olga Waksmann, Andrée Rothermel, Ugur Sahin, Janko Ciesla
Publikováno v:
Nature. 547:222-226
T cells directed against mutant neo-epitopes drive cancer immunity. However, spontaneous immune recognition of mutations is inefficient. We recently introduced the concept of individualized mutanome vaccines and implemented an RNA-based poly-neo-epit
Autor:
Matthias Renner, Silke Schüle, Juraj Hlavatý, Zbyněk Tonar, Helga Petznek, Sylvia Panitz, Kirsti Witter, Rudolf Moldzio, Björn-Philipp Kloke, Matthias Schweizer
Publikováno v:
Histochemistry and Cell Biology
Lentiviruses are suitable to transfer potential therapeutic genes into non-replicating cells such as neurons, but systematic in vivo studies on transduction of neural cells within the complete brain are missing. We analysed the distribution of transd
Autor:
Björn-Philipp Kloke, Matthias Miller, Andrea Mahr, Richard Rae, Sarah Kutscher, Veronika Jahndel
Publikováno v:
Cancer Immunology, Immunotherapy. 65:1277-1287
Autor:
Sarah Kutscher, Björn-Philipp Kloke, Cedrik M. Britten, Andrea Mahr, Richard Rae, Robert A. Jabulowsky
Publikováno v:
Cancer Immunology, Immunotherapy. 64:923-930
Autor:
Andrea Mahr, Cedrik M. Britten, Richard Rae, Ute E. Burkhardt, Pia Kvistborg, Björn-Philipp Kloke
Publikováno v:
Cancer Immunology, Immunotherapy. 63:749-755
Autor:
Björn Philipp Kloke, Sine Reker Hadrup, Cedrik M. Britten, Sarah Kutscher, Pia Kvistborg, Richard Rae
Publikováno v:
Cancer Immunology, Immunotherapy. 62:975-981
Autor:
Zeli Zhang, Qinyong Gu, Vasudevan, Ananda Jaguva, Hain, Anika, Björn-Philipp Kloke, Hasheminasab, Sascha, Mulnaes, Daniel, Sato, Kei, Cichutek, Klaus, Häussinger, Dieter, Bravo, Ignacio, Smits, Sander, Gohlke, Holger, Münk, Carsten
Additional file 1: Figure S1 . Cellular localization of feline A3s and FIV Vif. HOS cells were transfected with FcaA3Z2b, FcaA3Z3, or FcaA3Z2Z3 (all with HA-tag), together with FIV Vif-TLQAAA. To detect A3 (green) immunofluorescence, staining was per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059833132a9408efb2443f0b1132c679
Autor:
Björn-Philipp Kloke, Silke Schüle, Matthias Schweizer, Klaus Cichutek, Nina Wolfrum, Michael D. Mühlebach
Publikováno v:
The Journal of Gene Medicine. 12:446-452
Background Lentiviral vectors allow stable gene transfer into nonreplicating cells and are increasingly used in clinical gene therapy approaches. Vectors derived from different origins can show distinct target cell transduction properties. Therefore,
Autor:
Vinay K. Pathak, Mario Perkovic, Henning Hofmann, Martin Löchelt, Jörg Zielonka, Heike Ströver, Carsten Münk, Björn-Philipp Kloke, Ferdinand Kopietz, Klaus Cichutek, Gisbert Schneider, Rebecca A. Russell, Daniela Marino, Johannes Hermle, Dirk Lindemann, Stanislaw Schmidt, Benjamin Stauch
Publikováno v:
Journal of Biological Chemistry. 284:5819-5826
The APOBEC3 cytidine deaminases are part of the intrinsic defense of cells against retroviruses. Lentiviruses and spumaviruses have evolved essential accessory proteins, Vif and Bet, respectively, which counteract the APOBEC3 proteins. We show here t