Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Björn Tampe"'
Autor:
Sandip Kumar Rath, Gunsmaa Nyamsuren, Björn Tampe, David Sung-wen Yu, Melanie S. Hulshoff, Denise Schlösser, Sabine Maamari, Michael Zeisberg, Elisabeth M. Zeisberg
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background Cardiac fibrosis is the hallmark of all forms of chronic heart disease. Activation and proliferation of cardiac fibroblasts are the prime mediators of cardiac fibrosis. Existing studies show that ROS and inflammatory cytokines pro
Externí odkaz:
https://doaj.org/article/c9732583a636444882ccab2ad924f6f6
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionRapidly progressive glomerulonephritis (RPGN) is characterized by a rapid loss of kidney function, affecting both renal and overall patient survival. Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a small vessel
Externí odkaz:
https://doaj.org/article/d7c51c5908bb4b779dc2de2d31204ad8
Autor:
Leon Kanwischer, Xingbo Xu, Afifa Binta Saifuddin, Sabine Maamari, Xiaoying Tan, Fouzi Alnour, Björn Tampe, Thomas Meyer, Michael Zeisberg, Gerd Hasenfuss, Miriam Puls, Elisabeth M. Zeisberg
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Aortic stenosis (AS) is one of the most common cardiac diseases and major cause of morbidity and mortality in the elderly. Transcatheter aortic valve implantation (TAVI) is performed in such patients with symptomatic severe AS and
Externí odkaz:
https://doaj.org/article/958bd8ad517d4b9da55b49479aa0c653
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 713 (2024)
Involvement of the complement system is key to the pathogenesis of antineutrophil cytoplasmic antibody (ANCA)-associated renal vasculitis, but immunometabolic implications, especially on serum uric acid (UA) levels, still need to be elucidated. A tot
Externí odkaz:
https://doaj.org/article/67767815c70a4863826b356d6dde4ec3
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundImmune checkpoint inhibitors (ICIs) are novel drugs targeting programmed cell death protein 1-ligand 1 (PD-L1) or its receptor (PD-1). Enhancing the immune system has also been associated with a wide range of immune-related adverse events (
Externí odkaz:
https://doaj.org/article/5fda8c097734485db87d67cb9220ec3d
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a small vessel vasculitis often leading to critical illness by multi-organ failure. Data for patients with specifically ANCA-associated renal vasculitis requiring inte
Externí odkaz:
https://doaj.org/article/ff78bf281c0742ff964a56d1437ec8cd
Autor:
Ann-Kathrin Schäfer, Sascha Dierks, Moritz Schnelle, Peter Korsten, Samy Hakroush, Björn Tampe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Plasma exchange rapidly depletes pathogenic anti-neutrophil cytoplasmic autoantibodies (ANCAs) and is considered for induction therapy in severe ANCA-associated vasculitis. The aim of plasma exchange is to remove putative disease mediators from the c
Externí odkaz:
https://doaj.org/article/80612cb656804b39b9a3e34a090f3997
Autor:
Eva Baier, Peter Korsten, Arne Strauß, Kai-Martin Thoms, Tobias Overbeck, Philipp Ströbel, Björn Tampe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe advent of immune checkpoint inhibitors (ICIs) has powerfully broadened the scope of treatment options for malignancies with an ongoing increase of indications, but immune-related adverse events (irAEs) represent a serious threat to trea
Externí odkaz:
https://doaj.org/article/df855ddd13a44814a7d415374f144fc8
Autor:
Peter Korsten, Björn Tampe
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17066 (2023)
Diabetic nephropathy is a common microvascular complication of diabetes mellitus. It is characterized by progressive chronic kidney disease (CKD) with decline of kidney function by hyperfiltration. On a mechanistic level, activation of the complement
Externí odkaz:
https://doaj.org/article/90372afd0a2d42de8e9d0c8479678b3d
Autor:
Peter Korsten, Björn Tampe
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/24b8470c5d894587b24064c98ed992c7