Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Björn Rozell"'
Autor:
Thomas Lundåsen, Matteo Pedrelli, Bodil Bjørndal, Björn Rozell, Raoul V Kuiper, Lena Burri, Chiara Pavanello, Marta Turri, Jon Skorve, Rolf K Berge, Stefan E H Alexson, Veronika Tillander
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229322 (2020)
Tetradecylthioacetic acid (TTA) is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including activation of peroxisome p
Externí odkaz:
https://doaj.org/article/5b8fe50b259749dba3700bca2885356b
Autor:
Hui Li, Qi Yao, Alberto Garcia Mariscal, Xudong Wu, Justus Hülse, Esben Pedersen, Kristian Helin, Ari Waisman, Caroline Vinkel, Simon Francis Thomsen, Alexandra Avgustinova, Salvador Aznar Benitah, Paola Lovato, Hanne Norsgaard, Mette Sidsel Mortensen, Lone Veng, Björn Rozell, Cord Brakebusch
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Although IL-23 is expressed by psoriatic keratinocytes as well as immune cells, only the immune cell derived IL-23 is thought to be important for the development of psoriasis. Here the authors provide evidence that keratinocyte-produced IL-23 is suff
Externí odkaz:
https://doaj.org/article/ff608c11582641e39fc4e9d15e15de48
Autor:
Nina Fransén-Pettersson, Nadia Duarte, Julia Nilsson, Marie Lundholm, Sofia Mayans, Åsa Larefalk, Tine D Hannibal, Lisbeth Hansen, Anja Schmidt-Christensen, Fredrik Ivars, Susanna Cardell, Richard Palmqvist, Björn Rozell, Dan Holmberg
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159850 (2016)
Here we characterize a new animal model that spontaneously develops chronic inflammation and fibrosis in multiple organs, the non-obese diabetic inflammation and fibrosis (N-IF) mouse. In the liver, the N-IF mouse displays inflammation and fibrosis p
Externí odkaz:
https://doaj.org/article/9d3b933356d24c1daeda8f7b7fdf0e2d
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166353 (2016)
Automated blood sampling through a vascular catheter is a frequently utilized technique in laboratory mice. The potential immunological and physiological implications associated with this technique have, however, not been investigated in detail. The
Externí odkaz:
https://doaj.org/article/d3118c3d35f44e44af9405ec08b0d1c7
Autor:
Stefano Camnasio, Alessia Delli Carri, Angelo Lombardo, Iwona Grad, Caterina Mariotti, Alessia Castucci, Björn Rozell, Pietro Lo Riso, Valentina Castiglioni, Chiara Zuccato, Christelle Rochon, Yasuhiro Takashima, Giuseppe Diaferia, Ida Biunno, Cinzia Gellera, Marisa Jaconi, Austin Smith, Outi Hovatta, Luigi Naldini, Stefano Di Donato, Anis Feki, Elena Cattaneo
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 1, Pp 41-51 (2012)
Neuronal disorders, like Huntington's disease (HD), are difficult to study, due to limited cell accessibility, late onset manifestations, and low availability of material. The establishment of an in vitro model that recapitulates features of the dise
Externí odkaz:
https://doaj.org/article/23c2258d4ef340178a5b5ebcc449756a
Autor:
Anne Charlotte Teilmann, Andreas Nygaard Madsen, Birgitte Holst, Jann Hau, Björn Rozell, Klas Stig Peter Abelson
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113225 (2014)
Retro-bulbar sinus puncture and facial vein phlebotomy are two widely used methods for blood sampling in laboratory mice. However, the animal welfare implications associated with these techniques are currently debated, and the possible physiological
Externí odkaz:
https://doaj.org/article/dc2660634f584226af767f2e639f3c4a
Autor:
Marcella K Vaicik, Jill Thyboll Kortesmaa, Sofia Movérare-Skrtic, Jarkko Kortesmaa, Raija Soininen, Göran Bergström, Claes Ohlsson, Li Yen Chong, Björn Rozell, Margo Emont, Ronald N Cohen, Eric M Brey, Karl Tryggvason
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109854 (2014)
Obesity is a global epidemic that contributes to the increasing medical burdens related to type 2 diabetes, cardiovascular disease and cancer. A better understanding of the mechanisms regulating adipose tissue expansion could lead to therapeutics tha
Externí odkaz:
https://doaj.org/article/6dbfe82749764926b256929ef4c5b294
Autor:
Shashank Gupta, Regine Utoft, Henrik Hasseldam, Anja Schmidt-Christensen, Tine Dahlbaek Hannibal, Lisbeth Hansen, Nina Fransén-Pettersson, Noopur Agarwal-Gupta, Björn Rozell, Asa Andersson, Dan Holmberg
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76330 (2013)
Multiple Sclerosis (MS) is a progressive autoimmune inflammatory and demyelinating disease of the central nervous system (CNS). T cells play a key role in the progression of neuroinflammation in MS and also in the experimental autoimmune encephalomye
Externí odkaz:
https://doaj.org/article/84fff86e699949e4a9cb49560732a302
Autor:
Kari Högstrand, Eduar Hejll, Birgitta Sander, Björn Rozell, Lars-Gunnar Larsson, Alf Grandien
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31366 (2012)
Myc plays an important role in tumor development, including acute myeloid leukemia (AML). However, MYC is also a powerful inducer of apoptosis, which is one of the major failsafe programs to prevent cancer development. To clarify the relative importa
Externí odkaz:
https://doaj.org/article/d70c250b2e984de68637a04a1fdb7ff1
Autor:
Ahmad Pazirandeh, Taranum Sultana, Momina Mirza, Björn Rozell, Kjell Hultenby, Karin Wallis, Björn Vennström, Ben Davis, Anders Arner, Rainer Heuchel, Matthias Löhr, Lennart Philipson, Kerstin Sollerbrant
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20203 (2011)
To determine the normal function of the Coxsackievirus and Adenovirus Receptor (CAR), a protein found in tight junctions and other intercellular complexes, we constructed a mouse line in which the CAR gene could be disrupted at any chosen time point
Externí odkaz:
https://doaj.org/article/268a8f1461d34192a267e05ac6edc26b