Correction for Koel et al., Antigenic Variation of Clade 2.1 H5N1 Virus Is Determined by a Few Amino Acid Substitutions Immediately Adjacent to the Receptor Binding Site

Autor: Björn F. Koel, Stefan van der Vliet, David F. Burke, Theo M. Bestebroer, Eny E. Bharoto, I. Wayan W. Yasa, Inna Herliana, Brigitta M. Laksono, Kemin Xu, Eugene Skepner, Colin A. Russell, Guus F. Rimmelzwaan, Daniel R. Perez, Albert D. M. E. Osterhaus, Derek J. Smith, Teguh Y. Prajitno, Ron A. M. Fouchier

Publikováno v: mBio, Vol 5, Iss 4 (2014)

Externí odkaz: https://doaj.org/article/fac3987676f049b082f26ed7249dedbb

Epistatic interactions can moderate the antigenic effect o substitutions in haemagglutinin of influenza H3N2 virus

Autor: David F. Burke, Stefan van der Vliet, Ron A. M. Fouchier, Björn F. Koel, Albert D. M. E. Osterhaus, Theo M. Bestebroer, Guus F. Rimmelzwaan, Derek J. Smith

Publikováno v: Journal of General Virology, 100(5), 773-777. Microbiology Society
Journal of general virology, 100(5), 773-777. Society for General Microbiology
J Gen Virol

We previously showed that single amino acid substitutions at seven positions in haemagglutinin determined major antigenic change of influenza H3N2 virus. Here, the impact of two such substitutions was tested in 11 representative H3 haemagglutinins to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d13552bd18da700ab4c61bd8f7ee58
https://doi.org/10.1099/jgv.0.001263

Longitudinal sampling is required to maximize detection of intrahost A/H3N2 virus variants

Autor: René M Vigeveno, Tam Nguyen Thi Thanh, M Pater, M D de Jong, Dirk Eggink, Ha Manh Tuan, Alvin X. Han, Sebastian Maurer-Stroh, Le Quoc Thinh, H.R. van Doorn, Nguyen Thanh Hung, Nghiem My Ngoc, T Trinh, Kulkanya Chokephaibulkit, H T B Ngoc, Sylvie M. Koekkoek, Björn F. Koel, Tran Thi Ngoc Anh, Le Van Tan, Le Thanh Hai, R T C Lee, Pilaipan Puthavathana, Nguyen Van Kinh, Nguyen Van Vinh Chau

Publikováno v: Virus Evolution

Seasonal human influenza viruses continually change antigenically to escape from neutralizing antibodies. It remains unclear how genetic variation in the intrahost virus population and selection at the level of individual hosts translates to the fast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396fece9bef6e4c44f7fae2f23553a19
https://doi.org/10.1093/ve/veaa088

Disparate evolution of virus populations in upper and lower airways of mechanically ventilated patients

Autor: Björn F. Koel, de Jong, van Someren Gréve F, Colin A. Russell, René M Vigeveno, M Pater

In routine surveillance and diagnostic testing, influenza virus samples are typically collected only from the upper respiratory tract (URT) due to the invasiveness of sample collection from the lower airways. Very little is known about virus variatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b560d006167d5a00205185698fad97

Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution

Autor: Ron A. M. Fouchier, Mikhail Y. Eropkin, Theo M. Bestebroer, Colin A. Russell, Jan C. de Jong, Björn F. Koel, David F. Burke, Aeron C. Hurt, Eugene Skepner, Ian G. Barr, Stefan van der Vliet, Monique I. J. Spronken, Gaby Vervaet, Derek J. Smith, Guus F. Rimmelzwaan, Nicola S. Lewis, Albert D. M. E. Osterhaus, Gerben C. M. Zondag

Publikováno v: Science
Science; Vol 342
Science, 342(6161), 976-979. American Association for the Advancement of Science

Flu Drift Limited Five antigenic sites in the virus surface hemagglutinin protein, which together comprise 131 amino acid positions, are thought to determine the full scope of antigenic drift of influenza A virus. Koel et al. (p. 976 ) show that majo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482b7582a589a72207785ca6c41c650f