Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Björn A. Grüning"'
Publikováno v:
Journal of Cheminformatics, Vol 12, Iss 1, Pp 1-13 (2020)
Abstract This paper is a tutorial developed for the data analysis platform Galaxy. The purpose of Galaxy is to make high-throughput computational data analysis, such as molecular dynamics, a structured, reproducible and transparent process. In this t
Externí odkaz:
https://doaj.org/article/97899385994e41b0a076064064b6661b
Publikováno v:
Journal of Cheminformatics, Vol 12, Iss 1, Pp 1-7 (2020)
Abstract Here, we introduce the ChemicalToolbox, a publicly available web server for performing cheminformatics analysis. The ChemicalToolbox provides an intuitive, graphical interface for common tools for downloading, filtering, visualizing and simu
Externí odkaz:
https://doaj.org/article/44c41ccbe7794d758f00bf43872ae33e
Autor:
Thomas G Nührenberg, Jasmin Stöckle, Federico Marini, Mark Zurek, Björn A Grüning, Vladimir Benes, Lutz Hein, Franz-Josef Neumann, Christian Stratz, Marco Cederqvist, Willibald Hochholzer
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0260222 (2022)
BackgroundSepsis is associated with high platelet turnover and elevated levels of immature platelets. Changes in the platelet transcriptome and the specific impact of immature platelets on the platelet transcriptome remain unclear. Thus, this study s
Externí odkaz:
https://doaj.org/article/412c81b9eb1f449180b7f6b5c9cd35d6
Autor:
Subina Mehta, Valdemir M. Carvalho, Andrew T. Rajczewski, Olivier Pible, Björn A. Grüning, James E. Johnson, Reid Wagner, Jean Armengaud, Timothy J. Griffin, Pratik D. Jagtap
Publikováno v:
Viruses, Vol 14, Iss 10, p 2205 (2022)
The Coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in a major health crisis worldwide with its continuously emerging new strains, resulting in new viral variants that d
Externí odkaz:
https://doaj.org/article/54b988d980714905b8379386a16a7840
Autor:
Beatriz Serrano-Solano, Melanie C Föll, Cristóbal Gallardo-Alba, Anika Erxleben, Helena Rasche, Saskia Hiltemann, Matthias Fahrner, Mark J Dunning, Marcel H Schulz, Beáta Scholtz, Dave Clements, Anton Nekrutenko, Bérénice Batut, Björn A Grüning
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 5, p e1008923 (2021)
The COVID-19 pandemic is shifting teaching to an online setting all over the world. The Galaxy framework facilitates the online learning process and makes it accessible by providing a library of high-quality community-curated training materials, enab
Externí odkaz:
https://doaj.org/article/2203f8fac2ff4349a06b32591ebcd459
Autor:
Fidel Ramírez, Vivek Bhardwaj, Laura Arrigoni, Kin Chung Lam, Björn A. Grüning, José Villaveces, Bianca Habermann, Asifa Akhtar, Thomas Manke
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Although topologically associating domains (TADs) have been extensively investigated, it is not clear to what extent DNA sequence contributes to their formation. Here the authors develop software to identify high-resolution TAD boundaries and reveal
Externí odkaz:
https://doaj.org/article/f48cef696c874fc680f5d90d7c13d700
Autor:
Ralf Gilsbach, Martin Schwaderer, Sebastian Preissl, Björn A. Grüning, David Kranzhöfer, Pedro Schneider, Thomas G. Nührenberg, Sonia Mulero-Navarro, Dieter Weichenhan, Christian Braun, Martina Dreßen, Adam R. Jacobs, Harald Lahm, Torsten Doenst, Rolf Backofen, Markus Krane, Bruce D. Gelb, Lutz Hein
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
How the cardiac myocyte epigenome is rearranged during development, postnatal maturation and disease is not well understood. Here, the authors investigate the human cardiac myocyte epigenome during development and chronic heart failure and identify d
Externí odkaz:
https://doaj.org/article/e46b79bc29434dea9a7d59690c85ee94
Autor:
Stephan Nothjunge, Thomas G. Nührenberg, Björn A. Grüning, Stefanie A. Doppler, Sebastian Preissl, Martin Schwaderer, Carolin Rommel, Markus Krane, Lutz Hein, Ralf Gilsbach
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Chromatin is organized in higher order A and B compartments, reflecting active and inactive chromatin. Here, the authors provide evidence that in cardiac myocytes DNA methylation is established in preformed chromatin compartments and may be dispensab
Externí odkaz:
https://doaj.org/article/8b3e486861b4468d9a0816e1f96f830b
Autor:
Michael Lübbert, Christoph Plass, Dieter Weichenhan, Dietmar Pfeifer, Olga Grishina, Nadja Blagitko-Dorfs, Ruth Meier, Ulrike Bönisch, Lea Gutenkunst, Dennis Zimmer, Julia Stomper, Bettina Berberich, Björn A. Grüning, Julia Schüler, Gabriele Greve
Supplementary Information: Supplementary Figures 1-11, Supplementary Figure Legends, Supplementary Tables 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49dc5821022c16703878c9fcebb89670
https://doi.org/10.1158/0008-5472.22426905.v1
https://doi.org/10.1158/0008-5472.22426905.v1
Autor:
Michael Lübbert, Christoph Plass, Dieter Weichenhan, Dietmar Pfeifer, Olga Grishina, Nadja Blagitko-Dorfs, Ruth Meier, Ulrike Bönisch, Lea Gutenkunst, Dennis Zimmer, Julia Stomper, Bettina Berberich, Björn A. Grüning, Julia Schüler, Gabriele Greve
Hypomethylating agents (HMA) have become the backbone of nonintensive acute myeloid leukemia/myelodysplastic syndrome (AML/MDS) treatment, also by virtue of their activity in patients with adverse genetics, for example, monosomal karyotypes, often wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c6fdbf94468184f59ef641665a3b356
https://doi.org/10.1158/0008-5472.c.6512490.v1
https://doi.org/10.1158/0008-5472.c.6512490.v1