Prevalence of wild type transtyrethin cardiac amyloidosis in a heart failure clinic

Autor: Krister Lindmark, Björn Pilebro, Torbjörn Sundström, Per Lindqvist

Publikováno v: ESC Heart Failure, Vol 8, Iss 1, Pp 745-749 (2021)

Abstract Aims Wild type transthyretin amyloidosis (ATTRwt) has gained interest during recent years due to better diagnostic tools and the emergence of treatment options. Little is known about the prevalence of the disease. We aimed to investigate the

Externí odkaz: https://doaj.org/article/90716e29511f4d07ada9de8b3efede04

Cerebellar and Cerebral Amyloid Visualized by [18F]flutemetamol PET in Long-Term Hereditary V30M (p.V50M) Transthyretin Amyloidosis Survivors

Autor: Erica Irene Uneus, Christer Wilhelmsson, David Bäckström, Intissar Anan, Jonas Wixner, Björn Pilebro, Katrine Riklund, Mattias Ögren, Margareta Ögreen, Jan Axelsson, Ole B. Suhr, Torbjörn Sundström

Publikováno v: Frontiers in Neurology, Vol 13 (2022)

IntroductionHereditary transthyretin (ATTRv) amyloidosis caused by the V30M (p. V50M) mutation is a fatal, neuropathic systemic amyloidosis. Liver transplantation has prolonged the survival of patients and central nervous system (CNS) complications,

Externí odkaz: https://doaj.org/article/4f2230cb46d24ac39ec5c0e1062d9eaf

Association of Right Ventricular Myocardial Blood Flow With Pulmonary Pressures and Outcome in Cardiac Amyloidosis

Autor: Hendrik J. Harms, Tor Clemmensen, Sara Rosengren, Lars Tolbod, Björn Pilebro, Gerhard Wikström, Sven-Olof Granstam, Tanja Kero, Marcelo Di Carli, Steen Hvitfeldt Poulsen, Jens Sorensen

Publikováno v: Harms, H J, Clemmensen, T, Rosengren, S, Tolbod, L, Pilebro, B, Wikström, G, Granstam, S-O, Kero, T, Di Carli, M, Poulsen, S H & Sorensen, J 2023, ' Association of Right Ventricular Myocardial Blood Flow With Pulmonary Pressures and Outcome in Cardiac Amyloidosis ', JACC. Cardiovascular imaging . https://doi.org/10.1016/j.jcmg.2023.01.024

BACKGROUND: Cardiac amyloidosis (CA) is a restrictive and infiltrative cardiomyopathy, characterized by increased biventricular filling pressures and low output. Symptoms are predominantly of right heart origin. The role of right ventricular (RV) myo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c443c54c8bf64b2e9dd708b6be14e08c
https://pure.au.dk/portal/da/publications/association-of-right-ventricular-myocardial-blood-flow-with-pulmonarypressures-and-outcome-incardiac-amyloidosis(6633d0ee-867b-49a3-951d-f202357663e6).html

Cardiac transthyretin amyloidosis 99mTc-DPD SPECT correlates with strain echocardiography and biomarkers

Autor: Ole B. Suhr, Björn Pilebro, Viktor Löfbacka, Per Lindqvist, Jan Axelsson, Torbjörn Sundström

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging. 48:1822-1832

Purpose Hereditary transthyretin-amyloid amyloidosis (ATTRv) is an underdiagnosed condition commonly manifesting as congestive heart failure. Recently, scintigraphy utilizing DPD as a tracer was shown to identify ATTRv and wild-type ATTR cardiomyopat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c427ecc06e141d91ae886ff63a88cc
https://doi.org/10.1007/s00259-020-05144-8

Amyloid fibril composition type is consistent over time in patients with Val30Met (p. Val50Met) transthyretin amyloidosis

Autor: Intissar Anan, Ole B. Suhr, Katarzyna Liszewska, Jorge Mejia Baranda, Björn Pilebro, Jonas Wixner, Elisabet Ihse

Background We have previously shown that transthyretin (TTR) amyloidosis patients have amyloid fibrils of either of two compositions; type A fibrils consisting of large amounts of C-terminal TTR fragments in addition to full-length TTR, or type B fib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c552f08a1640ebdd47b9aa2721e0e137
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-193805