Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Björn, Nodin"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Programmed death-ligand 1 (PD-L1) expression on tumor cells is associated with poor prognosis in several malignancies, while partly contradictory and inconclusive results have been presented for colorectal cancer (CRC). This study
Externí odkaz:
https://doaj.org/article/a055855f16244387bf7a8e28cfcc7d49
Autor:
Malin Dahlgren, Barbara Lettiero, Hina Dalal, Kira Mårtensson, Alexander Gaber, Björn Nodin, Sofia K. Gruvberger-Saal, Lao H. Saal, Jillian Howlin
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-9 (2023)
Abstract Objective To investigate CITED1 as a potential biomarker of anti-endocrine response and breast cancer recurrence, given its previously determined role in mediating estrogen-dependant transcription. The study is a continuation of earlier work
Externí odkaz:
https://doaj.org/article/c9c6f678180546e18206439af403ab2a
Autor:
Christopher Godina, Somayeh Khazaei, Mattias Belting, Johan Vallon-Christersson, Björn Nodin, Karin Jirström, Karolin Isaksson, Ana Bosch, Helena Jernström
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0305222 (2024)
BackgroundCurrently, there are few treatment-predictive and prognostic biomarkers in triple-negative breast cancer (TNBC). Caveolin-1 (CAV1) is linked to chemoresistance and several important processes involved in tumor progression and metastasis, su
Externí odkaz:
https://doaj.org/article/b8af823829db42e29aa5801ab12f0df5
Autor:
Maria C. Svensson, Maja Svensson, Björn Nodin, David Borg, Charlotta Hedner, Claes Hjalmarsson, Karin Leandersson, Karin Jirström
Publikováno v:
Journal of Innate Immunity, Pp 1-14 (2022)
Tumor-associated macrophages (TAMs) have emerged as key players in tumor immunology but demonstrate a continuum of functional states being either tumor suppressive or promoting. Moreover, chemotherapeutic agents have been shown to alter the tumor mic
Externí odkaz:
https://doaj.org/article/c40cd281455e4ca2844560d7cd6332d3
Autor:
Sara Wahlin, Karolina Boman, Bruce Moran, Björn Nodin, William M. Gallagher, Emelie Karnevi, Karin Jirström
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background The response to neoadjuvant cisplatin-based chemotherapy (NAC) in muscle-invasive bladder cancer (MIBC) is impaired in up to 50% of patients due to chemoresistance, with no predictive biomarkers in clinical use. The proto-oncogene
Externí odkaz:
https://doaj.org/article/23e277afa0164cfbaae39771d287a33d
Autor:
Sofie Olsson Hau, Sara Wahlin, Sophie Cervin, Vilgot Falk, Björn Nodin, Jacob Elebro, Jakob Eberhard, Bruce Moran, William M Gallagher, Emelie Karnevi, Karin Jirström
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 1, Pp 65-77 (2022)
Abstract The outlook for patients with pancreatic cancer remains dismal. Treatment options are limited and chemotherapy remains standard of care, leading to only modest survival benefits. Hence, there is a great need to further explore the mechanisti
Externí odkaz:
https://doaj.org/article/636b8c745cbd42caa4d4e025acbae2fc
Autor:
Artur Mezheyeuski, Max Backman, Johanna Mattsson, Alfonso Martín-Bernabé, Chatarina Larsson, Ina Hrynchyk, Klara Hammarström, Simon Ström, Joakim Ekström, Siarhei Mauchanski, Salome Khelashvili, Amanda Lindberg, Margrét Agnarsdóttir, Per-Henrik Edqvist, Jutta Huvila, Ulrika Segersten, Per-Uno Malmström, Johan Botling, Björn Nodin, Charlotta Hedner, David Borg, Jenny Brändstedt, Hanna Sartor, Karin Leandersson, Bengt Glimelius, Anna Portyanko, Fredrik Ponten, Karin Jirström, Patrick Micke, Tobias Sjöblom
Publikováno v:
EBioMedicine, Vol 88, Iss , Pp 104452- (2023)
Summary: Background: Cancer immunity is based on the interaction of a multitude of cells in the spatial context of the tumour tissue. Clinically relevant immune signatures are therefore anticipated to fundamentally improve the accuracy in predicting
Externí odkaz:
https://doaj.org/article/21d6bb4dde9a4bcc8ada77b8353d03fb
Autor:
Christopher Godina, Vineesh Indira Chandran, Magdalena Barbachowska, Helga Tryggvadottir, Björn Nodin, Edward Visse, Signe Borgquist, Karin Jirström, Karolin Isaksson, Ana Bosch, Mattias Belting, Helena Jernström
Publikováno v:
Translational Oncology, Vol 22, Iss , Pp 101464- (2022)
Background: Caveolin-1 (CAV1) is associated with cholesterol-rich membrane raft domains and is a master regulator of cell signaling and membrane transport. Here, we investigated CAV1’s role in cellular compartments of breast cancer in relation to s
Externí odkaz:
https://doaj.org/article/d9798d3b49bb4a7c89a22c3134b4a34a
Autor:
Siker Kimbung, Maria Inasu, Tor Stålhammar, Björn Nodin, Karin Elebro, Helga Tryggvadottir, Maria Ygland Rödström, Karin Jirström, Karolin Isaksson, Helena Jernström, Signe Borgquist
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-13 (2020)
Abstract Background 27-Hydroxycholesterol (27HC) stimulates estrogen receptor-positive (ER+) breast cancer (BC) progression. Inhibiting the sterol 27-hydroxylase (CYP27A1) abrogates these growth-promoting effects of 27HC in mice. However, the signifi
Externí odkaz:
https://doaj.org/article/dc9b2df2276b447bbb83d11c19cb5da6
Autor:
Nina Andersson, Johan Ohlsson, Sara Wahlin, Björn Nodin, Karolina Boman, Sebastian Lundgren, Karin Jirström
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-12 (2020)
Abstract Background Screening across a multitude of normal and malignant tissues revealed an enhanced expression of lymphocyte antigen 6 superfamily member D (LY6D) in squamous epithelium and urothelium, as well as in malignancies derived therefrom.
Externí odkaz:
https://doaj.org/article/8cd3615ce1694fa59e4244c2099b701c