Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Björn, Gerlach"'
Autor:
Vibeke Fosse, Emanuela Oldoni, Florence Bietrix, Alfredo Budillon, Evangelos P. Daskalopoulos, Maddalena Fratelli, Björn Gerlach, Peter M. A. Groenen, Sabine M. Hölter, Julia M. L. Menon, Ali Mobasheri, Nikki Osborne, Merel Ritskes-Hoitinga, Bettina Ryll, Elmar Schmitt, Anton Ussi, Antonio L. Andreu, Emmet McCormack, on behalf of The PERMIT group
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Personalised medicine is a medical model that aims to provide tailor-made prevention and treatment strategies for defined groups of individuals. The concept brings new challenges to the translational step, both in clinical relevan
Externí odkaz:
https://doaj.org/article/ce60f85cb71e465188b1050e2365f3b2
Publikováno v:
F1000Research, Vol 10 (2021)
Reports of non-replicable research demand new methods of research data management. Electronic laboratory notebooks (ELNs) are suggested as tools to improve the documentation of research data and make them universally accessible. In a self-guided appr
Externí odkaz:
https://doaj.org/article/f9f5ec6bd2a1478c9e3a670c7e852bf4
Publikováno v:
F1000Research, Vol 10 (2021)
Reports of non-replicable research demand new methods of research data management. Electronic laboratory notebooks (ELNs) are suggested as tools to improve the documentation of research data and make them universally accessible. In a self-guided appr
Externí odkaz:
https://doaj.org/article/b2589c24818a4c92b1930a86009dcbdf
Autor:
Anton Bespalov, René Bernard, Anja Gilis, Björn Gerlach, Javier Guillén, Vincent Castagné, Isabel A Lefevre, Fiona Ducrey, Lee Monk, Sandrine Bongiovanni, Bruce Altevogt, María Arroyo-Araujo, Lior Bikovski, Natasja de Bruin, Esmeralda Castaños-Vélez, Alexander Dityatev, Christoph H Emmerich, Raafat Fares, Chantelle Ferland-Beckham, Christelle Froger-Colléaux, Valerie Gailus-Durner, Sabine M Hölter, Martine CJ Hofmann, Patricia Kabitzke, Martien JH Kas, Claudia Kurreck, Paul Moser, Malgorzata Pietraszek, Piotr Popik, Heidrun Potschka, Ernesto Prado Montes de Oca, Leonardo Restivo, Gernot Riedel, Merel Ritskes-Hoitinga, Janko Samardzic, Michael Schunn, Claudia Stöger, Vootele Voikar, Jan Vollert, Kimberley E Wever, Kathleen Wuyts, Malcolm R MacLeod, Ulrich Dirnagl, Thomas Steckler
Publikováno v:
eLife, Vol 10 (2021)
While high risk of failure is an inherent part of developing innovative therapies, it can be reduced by adherence to evidence-based rigorous research practices. Supported through the European Union’s Innovative Medicines Initiative, the EQIPD conso
Externí odkaz:
https://doaj.org/article/056d0e1179a847c792213de97e872285
Publikováno v:
eLife, Vol 9 (2020)
Core facilities are an effective way of making expensive experimental equipment available to a large number of researchers, and are thus well placed to contribute to efforts to promote good research practices. Here we report the results of a survey t
Externí odkaz:
https://doaj.org/article/c5f6e165c91a43a39203b27e9b16ca74
Autor:
Elena Demicheva, Yi-Fang Cui, Philip Bardwell, Stefan Barghorn, Martina Kron, Axel H. Meyer, Martin Schmidt, Björn Gerlach, Mary Leddy, Eve Barlow, Elizabeth O’Connor, Chee-Ho Choi, Lili Huang, Geertruida M. Veldman, Horea Rus, Alireza P. Shabanzadeh, Nardos G. Tassew, Philippe P. Monnier, Thomas Müller, Peter A. Calabresi, Hans Schoemaker, Bernhard K. Mueller
Publikováno v:
Cell Reports, Vol 10, Iss 11, Pp 1887-1898 (2015)
Repulsive guidance molecule A (RGMa) is a potent inhibitor of neuronal regeneration and a regulator of cell death, and it plays a role in multiple sclerosis (MS). In autopsy material from progressive MS patients, RGMa was found in active and chronic
Externí odkaz:
https://doaj.org/article/fd6bc223076f45f18b655b9a1c010a3d
Autor:
Michael J. Parnham, Pascal Schendel, Marc Bonin-Andresen, Martine C J Hofmann, Anton Bespalov, Ulrich Dirnagl, Olga Arbach, Christoph H. Emmerich, Katja Hempel, Lorena Martinez Gamboa, Björn Gerlach
Publikováno v:
Nature Reviews. Drug Discovery
Academic research plays a key role in identifying new drug targets, including understanding target biology and links between targets and disease states. To lead to new drugs, however, research must progress from purely academic exploration to the ini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda4f272f006331740c676d7e8c2797b
http://europepmc.org/articles/PMC7667479
http://europepmc.org/articles/PMC7667479
Autor:
Leonardo, Restivo, Björn, Gerlach, Michael, Tsoory, Lior, Bikovski, Sylvia, Badurek, Claudia, Pitzer, Isabelle C, Kos-Braun, Anne-Laure Mj, Mausset-Bonnefont, Jonathan, Ward, Michael, Schunn, Lucas Pjj, Noldus, Anton, Bespalov, Vootele, Voikar
Publikováno v:
EMBO Reports
EMBO Reports, EMBO Press, 2021, ⟨10.15252/embr.202153824⟩
EMBO Reports, EMBO Press, 2021, 22, pp.e53824. ⟨10.15252/embr.202153824⟩
EMBO reports, vol. 22, no. 12, pp. e53824
EMBO Reports, EMBO Press, 2021, ⟨10.15252/embr.202153824⟩
EMBO Reports, EMBO Press, 2021, 22, pp.e53824. ⟨10.15252/embr.202153824⟩
EMBO reports, vol. 22, no. 12, pp. e53824
International audience; Academic Core Facilities are optimally situated to improve the quality of preclinical research by implementing quality control measures and offering these to their users.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::09ef8a28ebad977236993d5f346766e2
http://hdl.handle.net/10138/337670
http://hdl.handle.net/10138/337670
Autor:
Björn Gerlach, Ernesto Prado Montes de Oca, Alexander Dityatev, Thomas Steckler, Merel Ritskes-Hoitinga, Gernot Riedel, Valerie Gailus-Durner, Patricia Kabitzke, Janko Samardzic, Claudia Stöger, Lior Bikovski, Raafat Fares, Martine C J Hofmann, Chantelle Ferland-Beckham, Sabine M. Hölter, Claudia Kurreck, Leonardo Restivo, Natasja de Bruin, Christoph H. Emmerich, Vootele Voikar, Michael Schunn, Małgorzata Pietraszek, Sandrine Bongiovanni, Heidrun Potschka, Piotr Popik, Kathleen Wuyts, Christelle Froger-Colléaux, Isabel A Lefevre, Fiona Ducrey, Malcolm R. Macleod, Jan Vollert, Kimberley E. Wever, Anja Gilis, Vincent Castagné, Javier Guillén, Anton Bespalov, Paul Moser, Esmeralda Castaños-Vélez, Martien J H Kas, René Bernard, María Arroyo-Araujo, Ulrich Dirnagl, Bruce Altevogt, Lee Monk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbc90a26852dc14f02daa4f94e0442e0
https://doi.org/10.7554/elife.63294.sa2
https://doi.org/10.7554/elife.63294.sa2
Autor:
Lior Bikovski, Raafat Fares, Anton Bespalov, Claudia Kurreck, Leonardo Restivo, Paul Moser, Chantelle Ferland-Beckham, Claudia Stöger, Patricia Kabitzke, Ernesto Prado Montes de Oca, Bruce Altevogt, Valerie Gailus-Durner, Sabine M. Hölter, Piotr Popik, Martine C J Hofmann, Vootele Voikar, Lee Monk, Michael Schunn, Alexander Dityatev, Janko Samardzic, Gernot Riedel, Thomas Steckler, Natasja de Bruin, Merel Ritskes-Hoitinga, Kathleen Wuyts, Christoph H. Emmerich, Heidrun Potschka, Vincent Castagné, Christelle Froger-Colléaux, Fiona Ducrey, Anja Gilis, Björn Gerlach, Jan Vollert, Kimberley E. Wever, Sandrine Bongiovanni, Esmeralda Castaños-Vélez, Martien J H Kas, René Bernard, Malcolm R. Macleod, Isabel A Lefevre, Javier Guillén, Małgorzata Pietraszek, María Arroyo-Araujo, Ulrich Dirnagl
Publikováno v:
Bespalov, A, Bernard, R, Gilis, A, Gerlach, B, Guillén, J, Castagné, V, Lefevre, I A, Ducrey, F, Monk, L, Bongiovanni, S, Altevogt, B, Arroyo-araujo, M, Bikovski, L, De Bruin, N, Castaños-vélez, E, Dityatev, A, Emmerich, C H, Fares, R, Ferland-beckham, C, Froger-colléaux, C, Gailus-durner, V, Hölter, S M, Hofmann, M C, Kabitzke, P, Kas, M J, Kurreck, C, Moser, P, Pietraszek, M, Popik, P, Potschka, H, Prado Montes De Oca, E, Restivo, L, Riedel, G, Ritskes-hoitinga, M, Samardzic, J, Schunn, M, Stöger, C, Voikar, V, Vollert, J, Wever, K E, Wuyts, K, Macleod, M R, Dirnagl, U & Steckler, T 2021, ' Introduction to the EQIPD quality system ', eLIFE, vol. 10 . https://doi.org/10.7554/eLife.63294
eLife, 10:e63294. ELIFE SCIENCES PUBLICATIONS LTD
eLife, Vol 10 (2021)
eLife 10, e63294 (2021). doi:10.7554/eLife.63294
eLife
Elife, 10
Bespalov, A, Bernard, R, Gilis, A, Gerlach, B, Guillén, J, Castagné, V, Lefevre, I A, Ducrey, F, Monk, L, Bongiovanni, S, Altevogt, B, Arroyo-Araujo, M, Bikovski, L, de Bruin, N, Castaños-Vélez, E, Dityatev, A, Emmerich, C H, Fares, R, Ferland-Beckham, C, Froger-Colléaux, C, Gailus-Durner, V, Hölter, S M, Hofmann, M C, Kabitzke, P, Kas, M J, Kurreck, C, Moser, P, Pietraszek, M, Popik, P, Potschka, H, Prado Montes de Oca, E, Restivo, L, Riedel, G, Ritskes-Hoitinga, M, Samardzic, J, Schunn, M, Stöger, C, Voikar, V, Vollert, J, Wever, K E, Wuyts, K, MacLeod, M R, Dirnagl, U & Steckler, T 2021, ' Introduction to the EQIPD quality system ', eLife, vol. 10, e63294 . https://doi.org/10.7554/eLife.63294
eLife, vol. 10, pp. e63294
eLife, 10:e63294. ELIFE SCIENCES PUBLICATIONS LTD
eLife, Vol 10 (2021)
eLife 10, e63294 (2021). doi:10.7554/eLife.63294
eLife
Elife, 10
Bespalov, A, Bernard, R, Gilis, A, Gerlach, B, Guillén, J, Castagné, V, Lefevre, I A, Ducrey, F, Monk, L, Bongiovanni, S, Altevogt, B, Arroyo-Araujo, M, Bikovski, L, de Bruin, N, Castaños-Vélez, E, Dityatev, A, Emmerich, C H, Fares, R, Ferland-Beckham, C, Froger-Colléaux, C, Gailus-Durner, V, Hölter, S M, Hofmann, M C, Kabitzke, P, Kas, M J, Kurreck, C, Moser, P, Pietraszek, M, Popik, P, Potschka, H, Prado Montes de Oca, E, Restivo, L, Riedel, G, Ritskes-Hoitinga, M, Samardzic, J, Schunn, M, Stöger, C, Voikar, V, Vollert, J, Wever, K E, Wuyts, K, MacLeod, M R, Dirnagl, U & Steckler, T 2021, ' Introduction to the EQIPD quality system ', eLife, vol. 10, e63294 . https://doi.org/10.7554/eLife.63294
eLife, vol. 10, pp. e63294
While high risk of failure is an inherent part of developing innovative therapies, it can be reduced by adherence to evidence-based rigorous research practices. Numerous analyses conducted to date have clearly identified measures that need to be take
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aef7c0ead5b242adb59f95192215766
http://hdl.handle.net/10044/1/95909
http://hdl.handle.net/10044/1/95909