Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Björn, Falkenburger"'
Autor:
Alexander Maximilian Bernhardt, Marc Oeller, Isabel Friedrich, Emre Kocakavuk, Eliana Nachman, Kevin Peikert, Malte Roderigo, Andreas Rossmann, Tabea Schröter, Lea Olivia Wilhelm, Tino Prell, Christoph van Riesen, Johanna Nieweler, Sabrina Katzdobler, Markus Weiler, Heike Jacobi, Tobias Warnecke, Inga Claus, Carla Palleis, Stephan Breimann, Björn Falkenburger, Moritz Brandt, Andreas Hermann, Jost-Julian Rumpf, Joseph Claßen, Günter Höglinger, Florin Gandor, Johannes Levin, Armin Giese, Annette Janzen, Wolfgang Hermann Oertel
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Disease-modifying therapeutics in the α-synucleinopathies multiple system atrophy (MSA) and Parkinson’s Disease (PD) are in early phases of clinical testing. Involving patients’ preferences including therapy-associated risk willingness
Externí odkaz:
https://doaj.org/article/4720aaf03e8d4e84ab5498ef530462a6
Autor:
Theresia Krieger, Leonie Jozwiak, Georg Ebersbach, Thorsten Suess, Björn Falkenburger, Tim Feige, Carsten Eggers, Tobias Warnecke, Winfried Scholl, Christian Schmidt-Heisch, Ann-Kristin Folkerts, Elke Kalbe, Ümran Sema Seven
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Parkinson’s disease (PD) significantly impacts the health-related quality of life of affected individuals and their relatives. In order to support the affected individuals and their families in coping with PD, it is essential to
Externí odkaz:
https://doaj.org/article/f21733f00e8c4d89abc8c8eaaae0f510
Autor:
Maren Freigang, Petra Steinacker, Claudia D. Wurster, Olivia Schreiber‐Katz, Alma Osmanovic, Susanne Petri, Jan C. Koch, Kevin Rostásy, André Huss, Hayrettin Tumani, Benedikt Winter, Björn Falkenburger, Albert C. Ludolph, Markus Otto, Andreas Hermann, René Günther
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 9, Pp 1437-1448 (2022)
Abstract Objective Activated astroglia is involved in the pathophysiology of neurodegenerative diseases and has also been described in animal models of spinal muscular atrophy (SMA). Given the urgent need of biomarkers for treatment monitoring of new
Externí odkaz:
https://doaj.org/article/c8b8f412413243a2be7148386f821a08
Autor:
Priyanka Bhatia, Marc Bickle, Amay A. Agrawal, Buster Truss, Aikaterina Nikolaidi, Kathrin Brockmann, Lydia Reinhardt, Stefanie Vogel, Eva M. Szegoe, Arun Pal, Andreas Hermann, Ivan Mikicic, Maximina Yun, Björn Falkenburger, Jared Sterneckert
Publikováno v:
Biology, Vol 13, Iss 1, p 58 (2024)
The degeneration of axon terminals before the soma, referred to as “dying back”, is a feature of Parkinson’s disease (PD). Axonal assays are needed to model early PD pathogenesis as well as identify protective therapeutics. We hypothesized that
Externí odkaz:
https://doaj.org/article/4952ffb943c34abcbcc6ad2a203b9ec1
Autor:
Vanessa Raeder, Lucia Batzu, Robert Untucht, Annekathrin Fehre, Alexandra Rizos, Valentina Leta, Renate Schmelz, Jochen Hampe, Sevasti Bostantjopoulou, Zoe Katsarou, Alexander Storch, Heinz Reichmann, Björn Falkenburger, K. Ray Chaudhuri, Lisa Klingelhoefer
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveA total of 48% of patients with Parkinson's disease (PD) present symptoms of gastrointestinal dysfunction, particularly constipation. Furthermore, gastrointestinal tract (GIT)-related non-motor symptoms (NMSs) appear at all stages of PD, can
Externí odkaz:
https://doaj.org/article/a07cfb7971934433a4a3018b017a9492
Autor:
Maren Freigang, Petra Steinacker, Claudia Diana Wurster, Olivia Schreiber-Katz, Alma Osmanovic, Susanne Petri, Jan Christoph Koch, Kevin Rostásy, Björn Falkenburger, Albert Christian Ludolph, Markus Otto, Andreas Hermann, René Günther
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-11 (2021)
Abstract Background Studies regarding the impact of (neuro)inflammation and inflammatory response following repetitive, intrathecally administered antisense oligonucleotides (ASO) in 5q-associated spinal muscular atrophy (SMA) are sparse. Increased r
Externí odkaz:
https://doaj.org/article/0cde2deffee34edd83dfefc691547d42
Autor:
Maren Freigang, Claudia D. Wurster, Tim Hagenacker, Benjamin Stolte, Markus Weiler, Christoph Kamm, Olivia Schreiber‐Katz, Alma Osmanovic, Susanne Petri, Alexander Kowski, Thomas Meyer, Jan C. Koch, Isabell Cordts, Marcus Deschauer, Paul Lingor, Elisa Aust, Daniel Petzold, Albert C. Ludolph, Björn Falkenburger, Andreas Hermann, René Günther
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 5, Pp 1049-1063 (2021)
Abstract Objective To determine whether serum creatine kinase activity (CK) and serum creatinine concentration (Crn) are prognostic and predictive biomarkers for disease severity, disease progression, and nusinersen treatment effects in adult patient
Externí odkaz:
https://doaj.org/article/b45a627a87f940ddbcd346930af78a59
Autor:
Enrico Michler, Daniel Kaiser, Kiriaki Eleftheriadou, Björn Falkenburger, Jörg Kotzerke, Sebastian Hoberück
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Background The functional 6-[18F]FDOPA positron emission tomography (PET) can be a helpful tool in differentiating parkinsonism with dopaminergic deficiency from clinically similar differential diagnoses. Furthermore, in T2*/susceptibility-w
Externí odkaz:
https://doaj.org/article/be14c02ad945416db3e3247e4d7f0975
Autor:
Sotirios Grigoriou, Pablo Martínez‐Martín, K. Ray Chaudhuri, Katarina Rukavina, Valentina Leta, Denise Hausbrand, Björn Falkenburger, Per Odin, Heinz Reichmann
Publikováno v:
Brain and Behavior, Vol 11, Iss 10, Pp n/a-n/a (2021)
Abstract Background Non‐motor symptoms (NMS) are integral to Parkinson's Disease (PD) and management remains a challenge. Safinamide is a novel molecule in relation to addressing NMS due to its multifocal mechanism of action with both dopaminergic
Externí odkaz:
https://doaj.org/article/e63969ecf78945b0ae7016789b8887e5
Autor:
Simone Mayer, Stefanie Fuchs, Madeleine Fink, Norbert Schäffeler, Stephan Zipfel, Franziska Geiser, Heinz Reichmann, Björn Falkenburger, Marco Skardelly, Martin Teufel
Publikováno v:
Frontiers in Psychology, Vol 12 (2021)
ObjectiveHopelessness and depression are strongly associated with suicidality. Given that physical and psychological outcomes can be altered with hope, hope is a therapeutic goal of increasing importance in the treatment of brain tumor patients. More
Externí odkaz:
https://doaj.org/article/d0e04710b12d4c91a81469ad42812681