Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Biyun Zhu"'
Autor:
Longlong Zhang, Hui Wang, Mengzhao Xun, Honghai Tang, Jinghan Wang, Jun Lv, Biyun Zhu, Yuxin Chen, Daqi Wang, Shaowei Hu, Ziwen Gao, Jianping Liu, Zheng-Yi Chen, Bing Chen, Huawei Li, Yilai Shu
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101154- (2023)
Pathogenic mutations in the OTOF gene cause autosomal recessive hearing loss (DFNB9), one of the most common forms of auditory neuropathy. There is no biological treatment for DFNB9. Here, we designed an OTOF gene therapy agent by dual-adeno-associat
Externí odkaz:
https://doaj.org/article/9201e8bb5dec4aaeb92965f6e0ea9271
Autor:
Niannian Xue, Xu Liu, Dan Zhang, Youming Wu, Yi Zhong, Jinxin Wang, Wenjing Fan, Haixia Jiang, Biyun Zhu, Xiyu Ge, Rachel V. L. Gonzalez, Liang Chen, Shun Zhang, Peilu She, Zhilin Zhong, Jianjian Sun, Xi Chen, Liren Wang, Zhimin Gu, Ping Zhu, Mingyao Liu, Dali Li, Tao P. Zhong, Xiaohui Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
There is a low efficiency of A-to-G base conversion in at specific positions using base editors. Here the authors fuse ABE8e with the Rad51 DNA-binding domain to generate a hyperactive ABE allowing improved A-to-G editing efficiency at the region pro
Externí odkaz:
https://doaj.org/article/ca3296a02cb34bdaa44b40fa174ab29c
Autor:
Lin Dong, Zilong Zhang, Biyun Zhu, Shenwei Li, Yan He, Yating Lou, Ping Li, Huajun Zheng, Zhengan Tian, Xia Ma
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Microbial inoculants are widely used in wastewater treatment, soil remediation, and biological control. Safety and compliance for active constituents are considered to be the most important measures of imported microbial inoculants. Microbial inocula
Externí odkaz:
https://doaj.org/article/b13773607e9e4ba1a70d5c8612291592
Autor:
Lei Yang, Xiaohui Zhang, Liren Wang, Shuming Yin, Biyun Zhu, Ling Xie, Qiuhui Duan, Huiqiong Hu, Rui Zheng, Yu Wei, Liangyue Peng, Honghui Han, Jiqin Zhang, Wenjuan Qiu, Hongquan Geng, Stefan Siwko, Xueli Zhang, Mingyao Liu, Dali Li
Publikováno v:
Protein & Cell, Vol 9, Iss 9, Pp 814-819 (2018)
Externí odkaz:
https://doaj.org/article/fa7c9b2ab6dd4090be907063efde78a7
Autor:
Lei Yang, Xiaohui Zhang, Liren Wang, Shuming Yin, Biyun Zhu, Ling Xie, Qiuhui Duan, Huiqiong Hu, Rui Zheng, Yu Wei, Liangyue Peng, Honghui Han, Jiqin Zhang, Wenjuan Qiu, Hongquan Geng, Stefan Siwko, Xueli Zhang, Mingyao Liu, Dali Li
Publikováno v:
Protein & Cell, Vol 10, Iss 9, Pp 700-700 (2019)
In the original publication the grant number is incorrectly published. The correct grant number should be read as “17140901600”. The corrected contents are provided in this correction article. This work was partially supported by grants from the
Externí odkaz:
https://doaj.org/article/a84057373ce24539a8ca49ca8cf4a49d
Autor:
Liang Chen, Biyun Zhu, Gaomeng Ru, Haowei Meng, Yongchang Yan, Mengjia Hong, Dan Zhang, Changming Luan, Shun Zhang, Hao Wu, Hongyi Gao, Sijia Bai, Changqing Li, Ruoyi Ding, Niannian Xue, Zhixin Lei, Yuting Chen, Yuting Guan, Stefan Siwko, Yiyun Cheng, Gaojie Song, Liren Wang, Chengqi Yi, Mingyao Liu, Dali Li
Publikováno v:
Nature Biotechnology. 41:663-672
Cytosine base editors (CBEs) efficiently generate precise C·G-to-T·A base conversions, but the activation-induced cytidine deaminase/apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (AID/APOBEC) protein family deaminase component ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1565ddacfea4b5ba0afcb5dc78b5381
https://doi.org/10.1038/s41587-022-01532-7
https://doi.org/10.1038/s41587-022-01532-7
Autor:
Liang Chen, Shun Zhang, Niannian Xue, Mengjia Hong, Xiaohui Zhang, Dan Zhang, Jing Yang, Sijia Bai, Yifan Huang, Haowei Meng, Hao Wu, Changming Luan, Biyun Zhu, Gaomeng Ru, Hongyi Gao, Liping Zhong, Meizhen Liu, Mingyao Liu, Yiyun Cheng, Chengqi Yi, Liren Wang, Yongxiang Zhao, Gaojie Song, Dali Li
Publikováno v:
Nature Chemical Biology. 19:101-110
Adenine base editors (ABEs) catalyze A-to-G transitions showing broad applications, but their bystander mutations and off-target editing effects raise safety concerns. Through structure-guided engineering, we found ABE8e with an N108Q mutation reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf1bbcdf74a35f0518357e9a34698b8
https://doi.org/10.1038/s41589-022-01163-8
https://doi.org/10.1038/s41589-022-01163-8
Autor:
Biyun Zhu, Margaret J. Wyszomirski
Publikováno v:
International Journal of Cultural Policy. :1-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfde3f987ab53be5d29d106d75cddf46
https://doi.org/10.1080/10286632.2022.2092102
https://doi.org/10.1080/10286632.2022.2092102
Publikováno v:
Journal of Clinical Nursing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b63e9a7f5d85f5dd589fedf82aff193e
https://doi.org/10.1111/jocn.16619
https://doi.org/10.1111/jocn.16619
Autor:
Liang Chen, Shun Zhang, Niannian Xue, Mengjia Hong, Xiaohui Zhang, Dan Zhang, Jing Yang, Sijia Bai, Yifan Huang, Haowei Meng, Hao Wu, Changming Luan, Biyun Zhu, Gaomeng Ru, Meizhen Liu, Mingyao Liu, Yiyun Cheng, Chengqi Yi, Gaojie Song, Liren Wang, Dali Li
Adenine base editors (ABEs) catalyze A-to-G transitions showing broad applications, but their bystander mutations and off-target editing effects raise the concerns of safety issues. Through structure-guided engineering, we found ABE8e with an N108Q m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4dd15a8163cf61d2da15964b4b0aeaf
https://doi.org/10.1101/2022.08.12.503700
https://doi.org/10.1101/2022.08.12.503700
