Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Bixi Jian"'
Autor:
Jean-Marie Dufour, Bixi Jian
Publikováno v:
SSRN Electronic Journal.
Existing literature cannot provide economic and financial networks with a unified measure to estimate network spillovers for empirical studies. In this paper, we propose a novel time series econometric method to measure high-dimensional directed and
Publikováno v:
Molecular Medicine. 18:209-214
Mitochondria play a critical role in metabolic homeostasis of a cell. Our recent studies, based on the reported interrelationship between c-Myc and Sirt1 (mammalian orthologue of yeast sir2 [silent information regulator 2]) expression and their role
Autor:
Dongquan Chen, Shaolong Yang, Irshad H. Chaudry, Lunyun Zou, Bixi Jian, Raghavan Raju, John C. Chatham
Publikováno v:
Molecular Medicine. 17:542-549
Cardiac dysfunction and mortality associated with trauma and sepsis increase with age. Mitochondria play a critical role in the energy demand of cardiac muscles, and thereby on the function of the heart. Specific molecular pathways responsible for mi
Autor:
Sreelatha Meleth, Bixi Jian, Kirby I. Bland, William E. Grizzle, Raghavan Raju, Chandrasekharam N. Nagineni, Irshad H. Chaudry
Publikováno v:
Cell Cycle. 8:3770-3776
Functional expression of KAL1 gene is critical in the migration of GnRH neurons from the olfactory placode to the hypothalamus in embryogenesis. This gene thus far has not been shown to play a functional role in any other physiological or pathologica
Autor:
Bixi Jian, Gary L. Johanning, Feng Wang-Johanning, Dung-Tsa Chen, Andra R. Frost, Ricardo Azerou, Danielle W. Lu
Publikováno v:
Cancer. 98:187-197
BACKGROUND The expression of human endogenous retrovirus (HERV) mRNA and proteins was associated recently with diseases that include human malignancies. The authors report that, in the current study, transcripts encoding the envelope region of an HER
Publikováno v:
Oncogene. 22:1528-1535
Human endogenous retroviruses (HERVs) comprise up to 8% of the human genome. In previous studies, we demonstrated that type 1 HERV-K envelope (env) transcripts are expressed in most human breast cancers, but not in normal breast tissues. In the curre
Publikováno v:
Molecular medicine (Cambridge, Mass.). 20
Severe hemorrhage leads to decreased blood flow to tissues resulting in decreased oxygen and nutrient availability affecting mitochondrial function. A mitoscriptome profiling study demonstrated alteration in several genes related to mitochondria, con
In a microarray analysis of human retinal pigment epithelial cells (HRPE) treated with TGF-β, in addition to the alteration of a number of known Extracellular matrix (ECM)-related genes regulated by TGF-β, we found a significant increase in the exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b3af1941175943f514dea8e7e21c9f
https://europepmc.org/articles/PMC3595383/
https://europepmc.org/articles/PMC3595383/
Publikováno v:
Aging and disease. 2(2)
Mitochondria are the major sites where energy is produced in the cell. Functions of organs such as the heart which has high energy demand are seriously affected by dysfunction of mitochondria. The functional changes in energy-dependent organs such as
The hypoxic conditions induced by reduced blood flow decreases oxygen availability in target tissues. Cellular hypoxia leads to mitochondrial dysfunction, decreased energy production, and increased production of reactive oxygen species. To determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3c782af002aebafaf6c90bd996dbfa
https://europepmc.org/articles/PMC3671386/
https://europepmc.org/articles/PMC3671386/