Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bitya Raphael"'
Autor:
Bitya Raphael-Mizrahi, Malka Attar-Namdar, Mukesh Chourasia, Maria G Cascio, Avital Shurki, Joseph Tam, Moshe Neuman, Neta Rimmerman, Zvi Vogel, Arie Shteyer, Roger G Pertwee, Andreas Zimmer, Natalya M Kogan, Itai Bab, Yankel Gabet
Publikováno v:
eLife, Vol 11 (2022)
The endocannabinoid system consists mainly of 2-arachidonoylglycerol and anandamide, as well as cannabinoid receptor type 1 and type 2 (CB2). Based on previous studies, we hypothesized that a circulating peptide previously identified as osteogenic gr
Externí odkaz:
https://doaj.org/article/b1b065666f49413c8b2026a4bcaff88e
Autor:
Jennifer Ana Iden, Bitya Raphael-Mizrahi, Aaron Naim, Albert Kolomansky, Tamar Liron, Drorit Neumann, Marilena Vered, Yankel Gabet
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 7773
Five million non-melanoma skin cancers occur globally each year, and it is one of the most common malignant cancers. The dysregulation of the endocannabinoid system, particularly cannabinoid receptor 2 (CB2), is implicated in skin cancer development,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939bd6fc872363797b3dcdace5464b9a
Autor:
Jennifer Ana Iden, Bitya Raphael-Mizrahi, Zamzam Awida, Aaron Naim, Dan Zyc, Tamar Liron, Melody Kasher, Gregory Livshits, Marilena Vered, Yankel Gabet
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 4060
Volume 24
Issue 4
Pages: 4060
The endocannabinoid system, particularly cannabinoid receptor 2 (CB2 in mice and CNR2 in humans), has controversial pathophysiological implications in colon cancer. Here, we investigate the role of CB2 in potentiating the immune response in colon can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384822d7e37e01e114edd0ad35ef3497
Autor:
Zamzam Awida, Sahar Hiram-Bab, Almog Bachar, Hussam Saed, Dan Zyc, Anton Gorodov, Nathalie Ben-Califa, Sewar Omari, Jana Omar, Liana Younis, Jennifer Ana Iden, Liad Graniewitz Visacovsky, Ida Gluzman, Tamar Liron, Bitya Raphael-Mizrahi, Albert Kolomansky, Martina Rauner, Ben Wielockx, Yankel Gabet, Drorit Neumann
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 12051
Erythropoietin (EPO) is a pleiotropic cytokine that classically drives erythropoiesis but can also induce bone loss by decreasing bone formation and increasing resorption. Deletion of the EPO receptor (EPOR) on osteoblasts or B cells partially mitiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cfdd73d3ec57e4d83a08da416fe890
Autor:
Bitya Raphael-Mizrahi, Malka Attar-Namdar, Mukesh Chourasia, Maria G Cascio, Avital Shurki, Joseph Tam, Moshe Neuman, Neta Rimmerman, Zvi Vogel, Arie Shteyer, Roger G Pertwee, Andreas Zimmer, Natalya M Kogan, Itai Bab, Yankel Gabet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24c5ecc3b06693d8e61eee26c040b598
https://doi.org/10.7554/elife.65834.sa2
https://doi.org/10.7554/elife.65834.sa2
Autor:
Bitya Raphael-Mizrahi, Malka Attar-Namdar, Mukesh Chourasia, Maria G Cascio, Avital Shurki, Joseph Tam, Moshe Neuman, Neta Rimmerman, Zvi Vogel, Arie Shteyer, Roger G Pertwee, Andreas Zimmer, Natalya M Kogan, Itai Bab, Yankel Gabet
Publikováno v:
eLife. 11
The endocannabinoid system consists mainly of 2-arachidonoylglycerol and anandamide, as well as cannabinoid receptor type 1 and type 2 (CB2). Based on previous studies, we hypothesized that a circulating peptide previously identified as osteogenic gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b054b47f93988f40244d8bc6d209c340
https://pubmed.ncbi.nlm.nih.gov/35604006
https://pubmed.ncbi.nlm.nih.gov/35604006
Autor:
Bitya Raphael-Mizrahi, Yankel Gabet
Publikováno v:
Current osteoporosis reports. 18(5)
Here, we overview the latest findings from studies investigating the skeletal endocannabinoid (EC) system and its involvement in bone formation and resorption. The endocannabinoid system consists of endogenous ligands, receptors, and enzymes. The mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bddfbe5eea11d9a6353a36155e5d767c
https://pubmed.ncbi.nlm.nih.gov/32705630
https://pubmed.ncbi.nlm.nih.gov/32705630
Publikováno v:
Journal of Cellular Physiology. 233:371-377
The inbred mouse strain C57BL/6 is commonly used for the generation of transgenic mouse and is a well established strain in bone research. Different vendors supply different substrains of C57BL/6J as wild-type animals when genetic drift did not incur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e477c405d691a46df29dcba8dc0f785
https://doi.org/10.1002/jcp.25895
https://doi.org/10.1002/jcp.25895
Autor:
Ana V. Villarreal Escudero, Raphael Mechoulam, Malka Attar-Namdar, Natalya M. Kogan, Silvina Friedlander-Barenboim, Yankel Gabet, Eitan Melamed, Neashan Mathavan, Itai Bab, Bitya Raphael, Saja Baraghithy, Aviva Breuer, Kathryn S. Stok, Alon Bajayo, Elad Wasserman, Ralph Müller, Hanna Isaksson, Rachel E. Sondergaard
Publikováno v:
Journal of Bone and Mineral Research. 30:1905-1913
Cannabinoid ligands regulate bone mass, but skeletal effects of cannabis (marijuana and hashish) have not been reported. Bone fractures are highly prevalent, involving prolonged immobilization and discomfort. Here we report that the major non-psychoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1975d78419884855e59fe9431b872773
https://doi.org/10.1002/jbmr.2513
https://doi.org/10.1002/jbmr.2513
Autor:
Pietro Marini, Raphael Mechoulam, Reem Smoum, Aviva Breuer, Naama Mussai, Mukesh Chourasia, Malka Attar-Namdar, Saja Baraghithy, Natalya M. Kogan, Bitya Raphael, Roger G. Pertwee, Daniele Bolognini, Maria Grazia Cascio, Avital Shurki, Itai Bab
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(28)
Activation of the CB2 receptor is apparently an endogenous protective mechanism. Thus, it restrains inflammation and protects the skeleton against age-related bone loss. However, the endogenous cannabinoids, as well as Δ(9)-tetrahydrocannabinol, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027b09517f67d4a4566c37d587c33e38
https://pubmed.ncbi.nlm.nih.gov/26124120
https://pubmed.ncbi.nlm.nih.gov/26124120