Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Bitolterol Mesylate"'
Publikováno v:
Annals of Allergy, Asthma & Immunology. 76:27-35
There have been numerous studies in asthmatic adults demonstrating the efficacy and safety of bitolterol mesylate metered-dose inhaler; however, only one additional study has examined bitolterol metered-dose inhaler in pediatric asthma.To establish t
Publikováno v:
Journal of Allergy and Clinical Immunology. 75:55-62
In this double-blind, parallel, single-dose study, bitolterol mesylate aerosol (three sprays, 1.11 mg) and albuterol aerosol (two sprays, 180 mcg) were compared for efficacy of bronchodilation in 120 adolescent and young adult patients with moderate
Autor:
R.K. Bush, C.J. Falliers, James P. Kemp, Edwin A. Bronsky, L M Mendelson, Thomas S. Mingo, Dockhorn Rj, M.J. Welch, Rebecca H. Buckley, C.W. Bierman, David G. Tinkelman, R.A. Nathan
Publikováno v:
Pediatric Asthma, Allergy & Immunology. 3:27-36
The objective of this study was to compare the efficacy and safety of bitolterol mesylate and isoproterenol hydrochloride, two sprays by metered-dose inhaler three times a day for 3 months in 240 asthmatic children ages 4–12 years. In this double-b
Autor:
H.Alice Orgel, James P. Kemp, Paul Chervinsky, Eli O. Meltzer, John H. Noyes, Thomas S. Mingo
Publikováno v:
Journal of Allergy and Clinical Immunology. 73:32-43
A higher incidence of fatal asthma after increased use of combined inhaled beta 2-agonists and theophylline has been attributed to additive cardiac toxicity of these agents. This study had three major objectives: first, to evaluate the efficacy and s
Publikováno v:
Chest. 91:533-539
Bitolterol mesylate, a new beta 2 adrenergic bronchodilator, is a “pro-drug” which is activated by esterases in the lung. In order to determine the optimal bronchodilator dose of bitolterol, six doses, (0.5 mg, 1.0 mg, 1.5 mg, 2.0 mg, 2.5 mg and
Autor:
Irving Kass, Thomas S. Mingo
Publikováno v:
Chest. 78:283-287
Bitolterol mesylate (WIN 37284) is α-[ tert -butylamino-methyl]-3,4-dihydroxybenzyl alcohol 3,4-di( p -toluate) methanesulfonate, a diester sympathomimetic amine bronchodilator. Bitolterol mesylate represents a new concept in sympathomimetic amine t
Autor:
Andrew B. C. Yu, William A. Hunke
Publikováno v:
American Journal of Health-System Pharmacy. 44:1392-1396
The particle-size distribution of bitolterol mesylate solution delivered by four types of compressed-air nebulizers was determined. Before nebulization, bitolterol mesylate solution 0.2% w/v was diluted to 0.0833% w/v with 0.9% sodium chloride soluti
Autor:
Mingo Ts, William E. Pierson, Shapiro Gg, Susannah B. Walker, Bierman Cw, Clifton T. Furukawa
Publikováno v:
Journal of Allergy and Clinical Immunology. 77:32-36
Exercise-induced asthma is a useful model for evaluating the activity and duration of action of pharmacologic agents of asthma. The main objective of this double-blind, crossover study was to determine the effect of the aerosolized beta-adrenergic ag
Autor:
Terry D. Wilson, Daniel F. Fogarty
Publikováno v:
Journal of chromatographic science. 26(2)
A reversed-phase ion-pairing HPLC method is developed for bitolterol mesylate (Tornalate, Winthrop-Breon) in aerosol dosage forms. Using data acquired by this method during a two-year period, the effect of ODS-3 column age on system suitability param
Autor:
Paul Chervinsky, Michael J. Neidl, Robert K. Bush, I. Leonard Bernstein, Robert A. Nathan, Bankim D. Bhatt, E Bronsky, Lawrence H. Repsher, Dockhorn Rj, Thomas S. Mingo, Jacob L. Pinnas, John J. Condemi
Publikováno v:
The Journal of allergy and clinical immunology. 79(5)
Bitolterol mesylate, 1.0 mg, or isoproterenol hydrochloride, 1.5 mg, was administered three times daily for 3 months in a double-blind, multicenter study via closed-port, intermittent-flow, compressor-driven nebulizer system (CPIF) to 182 nonsteroid-