Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Bitna Yi"'
Autor:
Andrew K. Evans, Pooneh M. Ardestani, Bitna Yi, Heui Hye Park, Rachel K. Lam, Mehrdad Shamloo
Publikováno v:
Neurobiology of Disease, Vol 146, Iss , Pp 105089- (2020)
Adrenergic systems regulate both cognitive function and immune function. The primary source of adrenergic signaling in the brain is norepinephrine (NE) neurons of the locus coeruleus (LC), which are vulnerable to age-related degeneration and are one
Externí odkaz:
https://doaj.org/article/aa54e9dbb4614cb9b0f954cfa4a041d1
Autor:
Bitna Yi, Alam Jahangir, Andrew K Evans, Denise Briggs, Kristine Ravina, Jacqueline Ernest, Amir B Farimani, Wenchao Sun, Jayakumar Rajadas, Michael Green, Evan N Feinberg, Vijay S Pande, Mehrdad Shamloo
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180319 (2017)
The beta-1 adrenergic receptor (ADRB1) is a promising therapeutic target intrinsically involved in the cognitive deficits and pathological features associated with Alzheimer's disease (AD). Evidence indicates that ADRB1 plays an important role in reg
Externí odkaz:
https://doaj.org/article/8f7924083cf944cba60e9ea23b9edaaf
Autor:
Pooneh Memar Ardestani, Rachel K. Lam, Mehrdad Shamloo, Bitna Yi, Andrew K. Evans, Heui Hye Park
Publikováno v:
Neurobiology of Disease, Vol 146, Iss, Pp 105089-(2020)
Neurobiol Dis
Neurobiol Dis
Adrenergic systems regulate both cognitive function and immune function. The primary source of adrenergic signaling in the brain is norepinephrine (NE) neurons of the locus coeruleus (LC), which are vulnerable to age-related degeneration and are one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b179d328d17ed6a99fcba6e4ae7f33
http://www.sciencedirect.com/science/article/pii/S0969996120303648
http://www.sciencedirect.com/science/article/pii/S0969996120303648
Autor:
Jessica Z. Chan, Jonathan T. Pierce, Pooneh Memar Ardestani, Luisa L. Scott, Stephen F. Martin, Bitna Yi, Sangeetha Iyer, Ashley Crisp, Gabriella Zuniga, Andrew K. Evans, James J. Sahn, Mehrdad Shamloo
Publikováno v:
Journal of Neurochemistry. 140:561-575
Accumulating evidence suggests that modulating the sigma 2 receptor (Sig2R) can provide beneficial effects for neurodegenerative diseases. Herein, we report the identification of a novel class of Sig2R binding ligands and their cellular and in vivo a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b968f3d4ba46d0ef43eb98e150b2bda
https://doi.org/10.1111/jnc.13917
https://doi.org/10.1111/jnc.13917
Publikováno v:
Journal of Environmental Science and Health, Part C. 34:33-56
Tobacco smoking is currently on the rise among women, and can pose a greater health risk. In order to understand the nature of the increase in smoking prevalence among women, we focused on the vulnerability of women to smoking behaviors--smoking cess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad62fa3ec69718c7d4446ed1542bd02
https://doi.org/10.1080/10590501.2015.1131539
https://doi.org/10.1080/10590501.2015.1131539
Autor:
Vijay S. Pande, Bitna Yi, Mehrdad Shamloo, Michael F. Green, Jacqueline Ernest, Evan N. Feinberg, Andrew K. Evans, Denise I. Briggs, Kristine Ravina, Amir Barati Farimani, Wenchao Sun, Alam Jahangir, Jayakumar Rajadas
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0180319 (2017)
PLoS ONE, Vol 12, Iss 7, p e0180319 (2017)
The beta-1 adrenergic receptor (ADRB1) is a promising therapeutic target intrinsically involved in the cognitive deficits and pathological features associated with Alzheimer's disease (AD). Evidence indicates that ADRB1 plays an important role in reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef584b2f58cefd45336892b625170d3
https://pubmed.ncbi.nlm.nih.gov/28746336
https://pubmed.ncbi.nlm.nih.gov/28746336
Autor:
Denise Isabelle, Briggs, Erwin, Defensor, Pooneh, Memar Ardestani, Bitna, Yi, Michelle, Halpain, Guy, Seabrook, Mehrdad, Shamloo
Publikováno v:
eNeuro
Emerging evidence suggests that endoplasmic reticulum (ER) stress may be involved in the pathogenesis of Alzheimer’s disease (AD). Recently, pharmacological modulation of the eukaryotic translation initiation factor-2 (eIF2α) pathway was achieved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e14d2818b8c64fe6f7d4da52be2cff0
https://pubmed.ncbi.nlm.nih.gov/28721361
https://pubmed.ncbi.nlm.nih.gov/28721361
Autor:
Dennis B. McKay, Sihui Long, Tatiana F. González-Cestari, Bitna Yi, Ryan E. Pavlovicz, Chenglong Li, Karl A. Werbovetz, Brandon J. Henderson
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:4730-4743
The present study describes our ongoing efforts toward the discovery of drugs that selectively target nAChR subtypes. We exploited knowledge on nAChR ligands and their binding site that were previously identified by our laboratory through virtual scr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7735c40f7ae68b84d289740cfb364b08
https://doi.org/10.1016/j.bmc.2013.03.082
https://doi.org/10.1016/j.bmc.2013.03.082
Autor:
Tiffany Nguyen, Pooneh Memar Ardestani, Laurence Coutellier, Bitna Yi, Andrew K. Evans, Mehrdad Shamloo
Publikováno v:
Neuropharmacology. 116
Degeneration of noradrenergic neurons occurs at an early stage of Alzheimer's Disease (AD). The noradrenergic system regulates arousal and learning and memory, and has been implicated in regulating neuroinflammation. Loss of noradrenergic tone may un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51752cfa93119246c40af460b1feb36
https://pubmed.ncbi.nlm.nih.gov/28089846
https://pubmed.ncbi.nlm.nih.gov/28089846
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 724:64-68
For health of future generation, fertile young women should be monitored for exposure of endocrine disrupting chemicals (EDCs). Among EDCs, bisphenol A (BPA) is suggested to induce reactive oxygen species (ROS) which play an important role in patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f5d71028603853c3f5992e2de2af641
https://doi.org/10.1016/j.mrgentox.2011.06.007
https://doi.org/10.1016/j.mrgentox.2011.06.007