Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Biswajyoti, Sahu"'
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103148- (2024)
Summary: Ectopic expression of lineage-specific transcription factors (TFs) of another cell type can induce cell fate reprogramming. However, the heterogeneity of reprogramming cells has been a challenge for data interpretation and model evaluation.
Externí odkaz:
https://doaj.org/article/141c243cab1945beb72c692b3788262c
Autor:
Konsta Karttunen, Divyesh Patel, Jihan Xia, Liangru Fei, Kimmo Palin, Lauri Aaltonen, Biswajyoti Sahu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Transposable elements (TE) are repetitive genomic elements that harbor binding sites for human transcription factors (TF). A regulatory role for TEs has been suggested in embryonal development and diseases such as cancer but systematic inves
Externí odkaz:
https://doaj.org/article/e401edfb92bd4d4ea50c4205e4044f5a
Autor:
Lisa Gawriyski, Eeva-Mari Jouhilahti, Masahito Yoshihara, Liangru Fei, Jere Weltner, Tomi T. Airenne, Ras Trokovic, Shruti Bhagat, Mari H. Tervaniemi, Yasuhiro Murakawa, Kari Salokas, Xiaonan Liu, Sini Miettinen, Thomas R. Bürglin, Biswajyoti Sahu, Timo Otonkoski, Mark S. Johnson, Shintaro Katayama, Markku Varjosalo, Juha Kere
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106172- (2023)
Summary: The paired-like homeobox transcription factor LEUTX is expressed in human preimplantation embryos between the 4- and 8-cell stages, and then silenced in somatic tissues. To characterize the function of LEUTX, we performed a multiomic charact
Externí odkaz:
https://doaj.org/article/1b78c910dbd44d44b717a1317ad6a139
Autor:
Pauliina M. Munne, Lahja Martikainen, Iiris Räty, Kia Bertula, Nonappa, Janika Ruuska, Hanna Ala-Hongisto, Aino Peura, Babette Hollmann, Lilya Euro, Kerim Yavuz, Linda Patrikainen, Maria Salmela, Juho Pokki, Mikko Kivento, Juho Väänänen, Tomi Suomi, Liina Nevalaita, Minna Mutka, Panu Kovanen, Marjut Leidenius, Tuomo Meretoja, Katja Hukkinen, Outi Monni, Jeroen Pouwels, Biswajyoti Sahu, Johanna Mattson, Heikki Joensuu, Päivi Heikkilä, Laura L. Elo, Ciara Metcalfe, Melissa R. Junttila, Olli Ikkala, Juha Klefström
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Reliable luminal estrogen receptor (ERα+) breast cancer models are limited. Here, the authors use patient derived breast epithelial and breast cancer explant cultures grown in several extracellular matrix scaffolds and show that ERα expression is r
Externí odkaz:
https://doaj.org/article/b09c6053c2ba40338196b223c9534247
Autor:
Kimmo Palin, Esa Pitkänen, Mikko Turunen, Biswajyoti Sahu, Päivi Pihlajamaa, Teemu Kivioja, Eevi Kaasinen, Niko Välimäki, Ulrika A. Hänninen, Tatiana Cajuso, Mervi Aavikko, Sari Tuupanen, Outi Kilpivaara, Linda van den Berg, Johanna Kondelin, Tomas Tanskanen, Riku Katainen, Marta Grau, Heli Rauanheimo, Roosa-Maria Plaketti, Aurora Taira, Päivi Sulo, Tuomo Hartonen, Kashyap Dave, Bernhard Schmierer, Sandeep Botla, Maria Sokolova, Anna Vähärautio, Kornelia Gladysz, Halit Ongen, Emmanouil Dermitzakis, Jesper Bertram Bramsen, Torben Falck Ørntoft, Claus Lindbjerg Andersen, Ari Ristimäki, Anna Lepistö, Laura Renkonen-Sinisalo, Jukka-Pekka Mecklin, Jussi Taipale, Lauri A. Aaltonen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
In this study the authors examine the allelic imbalance (AI) landscape of colorectal cancer, reporting loss of TP53 as a driver of AI. They use CRISPR-Cas9 screens to identify 79 genes (within AI regions) regulating cell growth and identify a network
Externí odkaz:
https://doaj.org/article/0d1e862be9834942b8b1513c12b2e466
Autor:
Tapio Visakorpi, Olli A. Jänne, Marika J. Linja, Visa Manni, Biswajyoti Sahu, Merja A. Helenius, Kati K. Waltering
Supplementary Figure Legends 1-6 from Increased Expression of Androgen Receptor Sensitizes Prostate Cancer Cells to Low Levels of Androgens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d148d6a50ca89803f41ffc14db27e7
https://doi.org/10.1158/0008-5472.22377740.v1
https://doi.org/10.1158/0008-5472.22377740.v1
Autor:
Tapio Visakorpi, Olli A. Jänne, Marika J. Linja, Visa Manni, Biswajyoti Sahu, Merja A. Helenius, Kati K. Waltering
Supplementary Tables 1-9 from Increased Expression of Androgen Receptor Sensitizes Prostate Cancer Cells to Low Levels of Androgens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa9e04997412445a9a249d682c9e0af
https://doi.org/10.1158/0008-5472.22377734
https://doi.org/10.1158/0008-5472.22377734
Autor:
Tapio Visakorpi, Olli A. Jänne, Marika J. Linja, Visa Manni, Biswajyoti Sahu, Merja A. Helenius, Kati K. Waltering
Supplementary Figures 1-6 from Increased Expression of Androgen Receptor Sensitizes Prostate Cancer Cells to Low Levels of Androgens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9ace04a3257e2f9eb07df8ec589994
https://doi.org/10.1158/0008-5472.22377737.v1
https://doi.org/10.1158/0008-5472.22377737.v1
Autor:
Konsta Karttunen, Divyesh Patel, Jihan Xia, Liangru Fei, Kimmo Palin, Lauri Aaltonen, Biswajyoti Sahu
Transposable elements (TE) are repetitive genomic elements that harbor binding sites for human transcription factors (TF). A regulatory role for TEs has been suggested in embryonal development and diseases such as cancer but systematic investigation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eee0e5b1483103781ef898def71a70c9
https://doi.org/10.1101/2022.12.16.520732
https://doi.org/10.1101/2022.12.16.520732
Cell fate can be reprogrammed by ectopic expression of lineage-specific transcription factors (TF). For example, few specialized cell types like neurons, hepatocytes and cardiomyocytes have been generated from fibroblasts by defined factors (Wanget a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd6ae32da685603fc48eba25f2c5350c
https://doi.org/10.1101/2022.11.16.516750
https://doi.org/10.1101/2022.11.16.516750