Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Biswajoy Roy-Chaudhuri"'
Autor:
Qing-Jun Luo, Jinsong Zhang, Pan Li, Qing Wang, Yue Zhang, Biswajoy Roy-Chaudhuri, Jianpeng Xu, Mark A. Kay, Qiangfeng Cliff Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Sequencing methods such as icSHAPE were developed to probe RNA structures transcriptome-wide in cells. To probe intact RNA structures, the authors develop icSHAPE-MaP and apply to Dicer-bound substrates showing that distance measuring is important fo
Externí odkaz:
https://doaj.org/article/583fc732877b412c963fcb1b0df984ec
Autor:
Yue Zhang, Qiangfeng Cliff Zhang, Qing Wang, Pan Li, Mark A. Kay, Jianpeng Xu, Qing-Jun Luo, Jinsong Zhang, Biswajoy Roy-Chaudhuri
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
It is known that an RNA’s structure determines its biological function, yet current RNA structure probing methods only capture partial structure information. The ability to measure intact (i.e., full length) RNA structures will facilitate investiga
Autor:
Biswajoy Roy-Chaudhuri, Qiangfeng Cliff Zhang, Wei Wei, Mei-Sze Chua, Hak Kyun Kim, Mark A. Kay, Shengchun Wang, Jianpeng Xu, Yue Zhang, Feijie Zhang, Pan Li, Samuel So, Gabriele Fuchs, Kirk Chu, Hyesuk Park, Peter Sarnow
Publikováno v:
Nature. 552:57-62
Transfer-RNA-derived small RNAs (tsRNAs; also called tRNA-derived fragments) are an abundant class of small non-coding RNAs whose biological roles are not well understood. Here we show that inhibition of a specific tsRNA, LeuCAG3′tsRNA, induces apo
Autor:
Mei-Sze Chua, Cliff Zhang, Pan Li, Yue Zhang, Biswajoy Roy-Chaudhuri, Peter Sarnow, Shengchun Wang, Mark A. Kay, Hyesuk Park, Jianpeng Xu, Gabriele Fuchs, Wei Wei, Kirk Chu, Feijie Zhang, Samuel So, Hak Kyun Kim
Publikováno v:
Cancer Research. 78:LB-390
There are tens of thousands of different transfer RNA-derived small RNAs (tsRNAs) of 18-40 nucleotides in length in mammalian cells. In recent years there is accumulating evidence suggesting that these RNAs can play different yet important roles in g
Publikováno v:
Nature structural & molecular biology
Processing of microRNAs (miRNAs) from their precursors to their biologically active mature forms is regulated during development and cancer. We show that mouse pri- or pre-miR-151 can bind to and compete with mature miR-151-5p and miR-151-3p for bind
Autor:
Kayla C Kemp, Hak Kyun Kim, Kayam Chak, Mark A. Kay, Brenda E. Porter, Biswajoy Roy-Chaudhuri
MicroRNA-21 (miR-21) is consistently up-regulated in various neurological disorders, including epilepsy. Here, we show that the biogenesis of miR-21 is altered following pilocarpine-induced status epilepticus (SE) with an increase in precursor miR-21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33d3b87584ec1d427d7a4c58a435e83
https://europepmc.org/articles/PMC5331941/
https://europepmc.org/articles/PMC5331941/
Publikováno v:
Proceedings of the National Academy of Sciences. 107:4567-4572
Ribosomal protein S5 is critical for small ribosomal subunit (SSU) assembly and is indispensable for SSU function. Previously, we identified a point mutation in S5, (G28D) that alters both SSU formation and translational fidelity in vivo, which is un
Publikováno v:
Molecular Microbiology
A specific mutation of Escherichia coli ribosomal protein S5, in which glycine is changed to aspartate at position 28 [S5(G28D)], results in cold sensitivity and defects in ribosome biogenesis and translational fidelity. In an attempt to understand t
Publikováno v:
Ribosomes ISBN: 9783709102145
In an actively growing Escherichia coli cell, the rates of ribosome production and cell growth are directly correlated. It has been estimated that approximately 40% of the available energy during exponential growth of E. coli is devoted to ribosome b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10794f04e36de9896b60c1447b5ad00c
https://doi.org/10.1007/978-3-7091-0215-2_21
https://doi.org/10.1007/978-3-7091-0215-2_21
Publikováno v:
RNA (New York, N.Y.). 12(12)
S5 is a small subunit ribosomal protein (r-protein) linked to the functional center of the 30S ribosomal subunit. In this study we have identified a unique amino acid mutation in Escherichia coli S5 that produces spectinomycin-resistance and cold sen