Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Biswajit Kundu"'
Autor:
Biswajit Kundu, Szabolcs Dvorácskó, Abhishek Basu, Lenny Pommerolle, Kyu Ah Kim, Casey M. Wood, Eve Gibbs, Madeline Behee, Nadya I. Tarasova, Resat Cinar, Malliga R. Iyer
Publikováno v:
Molecules, Vol 29, Iss 13, p 3036 (2024)
The inhibition of soluble epoxide hydrolase (sEH) can reduce the level of dihydroxyeicosatrienoic acids (DHETs) effectively maintaining endogenous epoxyeicosatrienoic acids (EETs) levels, resulting in the amelioration of inflammation and pain. Conseq
Externí odkaz:
https://doaj.org/article/082c48c1d63a4249a7e91acb02de8c5e
Publikováno v:
Advanced Science, Vol 9, Iss 20, Pp n/a-n/a (2022)
Abstract Developing high performance, low‐cost solid‐state light emitters in the telecom wavelength bandwidth is of paramount importance for infrared light‐based communications. Colloidal quantum dot (CQD) based light emitting diodes (LEDs) hav
Externí odkaz:
https://doaj.org/article/de576c40d43e4d528cf4e6c7b8656491
Autor:
Ayan Mukherjee, Snehasis Mishra, Naveen Kumar Kotla, Krishnendu Manna, Swarnali Roy, Biswajit Kundu, Debomita Bhattacharya, Krishna Das Saha, Arindam Talukdar
Publikováno v:
ACS Omega, Vol 4, Iss 4, Pp 7285-7298 (2019)
Externí odkaz:
https://doaj.org/article/e291baa441be4f1ea67a2c5bb39869f7
Autor:
Sourav Pal, Vinay Kumar, Biswajit Kundu, Debomita Bhattacharya, Nagothy Preethy, Mamindla Prashanth Reddy, Arindam Talukdar
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 291-310 (2019)
Camptothecin (CPT), a natural product and its synthetic derivatives exert potent anticancer activity by selectively targeting DNA Topoisomerase I (Top1) enzyme. CPT and its clinically approved derivatives are used as Top1 poisons for cancer therapy s
Externí odkaz:
https://doaj.org/article/0515aabdf6dc43bdbd8b6a93b16597cd
Publikováno v:
Physical Review B. 107
Publikováno v:
Physical Review Materials. 7
Autor:
Dipyaman Ganguly, Ayan Mukherjee, Dipika Sarkar, Bishnu Prasad Sinha, Kantubhukta Ramarao, Biswajit Kundu, Kasireddy Nagireddy, Nirmal Das, Sourav Pal, Deblina Raychaudhuri, Purbita Bandopadhyay, Debdeep Dey, Arindam Talukdar
Publikováno v:
Journal of Medicinal Chemistry. 64:9279-9301
Several toll-like receptors (TLRs) reside inside endosomes of specific immune cells-among them, aberrant activation of TLR7 and TLR9 is implicated in myriad contexts of autoimmune diseases, making them promising therapeutic targets. However, small-mo
Publikováno v:
ACS omega. 7(35)
We report the development of a one-pot Bunte's reaction-enabled expeditious platform under aqueous conditions for the scalable conversion of sulfonylureas to synthetically versatile thio-sulfonylureas. The reaction was further propagated in the same
Publikováno v:
Expert opinion on therapeutic patents. 32(6)
Biological effects mediated by the CYP450 arm of arachidonate cascade implicate the enzyme-soluble epoxide hydrolase (sEH) in hydrolyzing anti-inflammatory epoxy fatty acids to pro-inflammatory diols. Hence, inhibiting the sEH offers a therapeutic ap
Autor:
Mousumi Mitra, Dipyaman Ganguly, Barnali Paul, Ayan Mukherjee, Bishnu Prasad Sinha, Purbita Bandopadhyay, Arindam Talukdar, Deblina Raychaudhuri, Biswajit Kundu
Publikováno v:
Journal of Medicinal Chemistry. 63:4776-4789
Toll-like receptor 7 (TLR7) is an established therapeutic target in myriad autoimmune disorders, but no TLR7 antagonist is available for clinical use to date. Herein, we report a purine scaffold TLR7 antagonist, first-of-its-kind to our knowledge, wh