Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Biswadip, Das"'
Publikováno v:
Microbial Cell, Vol 11, Pp 155-186 (2024)
In Saccharomyces cerevisiae, polyadenylated forms of mature (and not precur-sor) small non-coding RNAs (sncRNAs) those fail to undergo proper 3-end mat-uration are subject to an active degradation by Rrp6p and Rrp47p, which does not require the in
Externí odkaz:
https://doaj.org/article/5f5ae54a84e24023843797e2aeaca3b7
Publikováno v:
Microbial Cell, Vol 4, Iss 7, Pp 212-228 (2017)
The cellular transcriptome is shaped by both the rates of mRNA synthesis in the nucleus and mRNA degradation in the cytoplasm under a specified condition. The last decade witnessed an exciting development in the field of post-transcriptional regulati
Externí odkaz:
https://doaj.org/article/a6fc74956f9f42598546fe2daba0350b
Publikováno v:
Nucleic Acids Research
Nuclear degradation of aberrant mRNAs in Saccharomyces cerevisiae is accomplished by the nuclear exosome and its cofactors TRAMP/CTEXT. Evidence from this investigation establishes a universal role of the Nrd1p-Nab3p-Sen1p (NNS) complex in the nuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb7fbdaf8e211727ede692ebf4b39e0
http://europepmc.org/articles/PMC8599857
http://europepmc.org/articles/PMC8599857
Induction of unfolded protein response (UPR) involves activation of transcription factor Hac1p that facilitates the transactivation of genes encoding ER-chaperones. Hac1p is encoded by HAC1 pre-mRNA harboring an intron and a bipartite element (BE) at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f0cea049f06f1026a2b3a59d0c69786
https://doi.org/10.1101/2022.08.18.504421
https://doi.org/10.1101/2022.08.18.504421
Autor:
Sunirmal, Paira, Biswadip, Das
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2378
Nuclear degradation of pre-HAC1 mRNA and its subsequent targeting plays a vital role in the activation as well as attenuation of Unfolded Protein Response (UPR) in Saccharomyces cerevisiae. Accurate measurement of the degradation of precursor HAC1 mR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::382e461e6b2ef956ed878923d975bb2c
https://pubmed.ncbi.nlm.nih.gov/34985698
https://pubmed.ncbi.nlm.nih.gov/34985698
Autor:
Sunirmal Paira, Biswadip Das
Publikováno v:
Methods in Molecular Biology ISBN: 9781071617311
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11bed8881950a3ead0fc589c0495bc35
https://doi.org/10.1007/978-1-0716-1732-8_9
https://doi.org/10.1007/978-1-0716-1732-8_9
In Saccharomyces cerevisiae, DRN (Decay of RNA in the Nucleus) requiring Cbc1/2p, Tif4631p, and Upf3p promotes the exosomal degradation of aberrantly long 3′-extended-, export-defective transcripts and a small group of normal (special) mRNAs. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49d06a99d2a76e23830124e1008f52c5
https://doi.org/10.1101/2021.03.29.437469
https://doi.org/10.1101/2021.03.29.437469
InSaccharomyces cerevisiae,the nuclear exosome/Rrp6p/TRAMP participates in the 3’-end processing of several precursor non-coding RNAs. Here we demonstrate that the depletion of nucleus-specific 3’→5’ exoribonuclease Rrp6p and its cofactor, Rr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14a962db31295ff25cfbe1e20f25f618
https://doi.org/10.1101/2020.12.13.422512
https://doi.org/10.1101/2020.12.13.422512
In all eukaryotes, selective nuclear degradation of aberrant mRNAs by nuclear exosome and its cofactors TRAMP, and CTEXT contribute to the fidelity of the gene expression pipeline. In the model eukaryote,Saccharomyces cerevisiae, the Nrd1p-Nab3p-Sen1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58e5bba7abac823dc0f2f75f17396c91
https://doi.org/10.1101/2020.06.02.129106
https://doi.org/10.1101/2020.06.02.129106