Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Bistra Kostova"'
Publikováno v:
Gels, Vol 10, Iss 4, p 217 (2024)
Aripiprazole (ARZ) is a medication used for the treatment of various diseases such as schizophrenia, bipolar disorder, major depressive disorder, autism, and Tourette’s syndrome. Despite its therapeutic benefits, ARZ is characterized by a poor wate
Externí odkaz:
https://doaj.org/article/7b2d02507a2c4e778a5172de559b7829
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2328 (2023)
In this study, a series of novel poly(2-hydroxyethyl methacrylate) (PHEMA)/poly(N,N′-dimethylacrylamide) (PDMAM) interpenetrating polymer networks (IPNs) were synthesized and studied as potential drug delivery systems of dexamethasone sodium phosph
Externí odkaz:
https://doaj.org/article/2ba3812253034344bd7383f53327d238
Publikováno v:
Gels, Vol 9, Iss 6, p 470 (2023)
Dexamethasone (DXM) is a highly potent and long-acting synthetic glucocorticoid with anti-inflammatory, anti-allergic, and immunosuppressive effects. However, the systemic application of DXM can cause undesirable side effects: sleep disorders, nervou
Externí odkaz:
https://doaj.org/article/099497f4e0d7424d8627559892591176
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 829 (2023)
Natural alkaloid galantamine is widely used for the treatment of mild to moderate Alzheimer’s dementia. Galantamine hydrobromide (GH) is available as fast-release tablets, extended-release capsules, and oral solutions. However, its oral delivery ca
Externí odkaz:
https://doaj.org/article/bf7b7953e4254695959d99b84f2541c2
Publikováno v:
Gels, Vol 8, Iss 12, p 780 (2022)
Nowadays, modern pharmaceutical investigations are directed toward the design and production of drug delivery systems for achieving prolonged and controlled drug delivery. In this respect, the use of interpenetrating polymer networks (IPNs) is an opp
Externí odkaz:
https://doaj.org/article/b7e9876d6f254937b39004e8c1fd38ac
Publikováno v:
Pharmaceutical nanotechnology.
Abstract: Polyacrylic and polymethacrylic acids in combination with polymers such as polyacrylamide provide the ability for controlled and sustained drug delivery since they represent pH- and temperature responsiveness. In addition, the synthesis tec
Autor:
Dilyana Georgieva, Dimitar Rachev, Sijka Ivanova, Krasimira Ivanova-Mileva, Bistra Kostova, Darinka Christova
Publikováno v:
Colloid and Polymer Science. 298:377-384
Natural alkaloid galantamine is widely used for the treatment of Alzheimer’s disease and various other memory impairments. Galantamine hydrobromide (GH) is available as fast-release tablets, extended-release capsules, and oral solution. However, or
Publikováno v:
Polymer International. 66:1306-1311
Publikováno v:
Macromolecular Chemistry and Physics. 222:2100004
Autor:
Konstantin Balashev, Dilyana Georgieva, Bistra Kostova, George Georgiev, Dimitar Rachev, Elena Kamenska
Publikováno v:
AAPS PharmSciTech. 18:166-174
Nowadays, the modern pharmaceutical investigations are directed toward obtaining of new polymer micro- and nano-sized drug delivery carriers. In this respect, the use of hydrogel carriers based on polyzwitterions (PZIs) is an opportunity in the prepa