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Technical Validation and Utility of an HLA Class II Tetramer Assay for Type 1 Diabetes: A Multicenter Study.

Autor: Ettinger RA; Center for Translational Immunology, Benaroya Research Institute, Seattle, WA 98101, USA., Buitinga M; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, 3000 Leuven, Belgium., Vandamme C; Department of Clinical Microbiology, Institute of Clinical Medicine, University of Eastern Finland, 70210 Kuopio, Finland., Afonso G; Diabetes and Autoimmunity Research Laboratory, Université Paris Cité, Institut Cochin, CNRS, INSERM, 75014 Paris, France., Gomez R; Center for Translational Immunology, Benaroya Research Institute, Seattle, WA 98101, USA., Arribas-Layton D; Department of Immunology and Theranostics, City of Hope Medical Center, Beckman Research Institute, Duarte, CA 91010, USA., Bissenova S; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, 3000 Leuven, Belgium., Speake C; Center for Interventional Immunology, Benaroya Research Institute, Seattle, WA 98101, USA., Reijonen H; Department of Immunology and Theranostics, City of Hope Medical Center, Beckman Research Institute, Duarte, CA 91010, USA., Kinnunen T; Department of Clinical Microbiology, Institute of Clinical Medicine, University of Eastern Finland, 70210 Kuopio, Finland.; Eastern Finland Laboratory Centre (ISLAB), 70210 Kuopio, Finland., Overbergh L; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, 3000 Leuven, Belgium., Mallone R; Diabetes and Autoimmunity Research Laboratory, Université Paris Cité, Institut Cochin, CNRS, INSERM, 75014 Paris, France.; Department of Internal Medicine, Assistance Publique Hôpitaux de Paris, Service de Diabétologie et Immunologie Clinique, Cochin Hospital, 75014 Paris, France., Kwok WW; Center for Translational Immunology, Benaroya Research Institute, Seattle, WA 98101, USA., James EA; Center for Translational Immunology, Benaroya Research Institute, Seattle, WA 98101, USA.

Publikováno v: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2023 Dec 21; Vol. 109 (1), pp. 183-196.

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Akademický článek

A Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis-Based Antigen-Specific Immunotherapy in New-Onset Type 1 Diabetes.

Autor: Sassi G; Clinical and Experimental Endocrinology, Chrometa, KU Leuven, Leuven, Belgium., Licata G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS, Toscana Life Science, Siena, Italy., Ventriglia G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS, Toscana Life Science, Siena, Italy., Wouters A; Clinical and Experimental Endocrinology, Chrometa, KU Leuven, Leuven, Belgium., Lemaitre P; Clinical and Experimental Endocrinology, Chrometa, KU Leuven, Leuven, Belgium., Seurinck R; Data Mining and Modelling for Biomedicine, VIB Center for Inflammation Research, Ghent, Belgium.; Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium., Mori A; Tuscany Centre for Precision Medicine, Siena, Italy., Grieco GE; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS, Toscana Life Science, Siena, Italy., Bissenova S; Clinical and Experimental Endocrinology, Chrometa, KU Leuven, Leuven, Belgium., Ellis D; Clinical and Experimental Endocrinology, Chrometa, KU Leuven, Leuven, Belgium., Caluwaerts S; Precigen ActoBio, Zwijnaarde (Ghent), Ghent, Belgium., Rottiers P; Precigen ActoBio, Zwijnaarde (Ghent), Ghent, Belgium., Vandamme N; Data Mining and Modelling for Biomedicine, VIB Center for Inflammation Research, Ghent, Belgium.; VIB Single Cell Core, Leuven-Ghent, Ghent, Belgium., Mathieu C; Clinical and Experimental Endocrinology, Chrometa, KU Leuven, Leuven, Belgium., Dotta F; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS, Toscana Life Science, Siena, Italy.; Tuscany Centre for Precision Medicine, Siena, Italy., Gysemans C; Clinical and Experimental Endocrinology, Chrometa, KU Leuven, Leuven, Belgium., Sebastiani G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.; Fondazione Umberto Di Mario ONLUS, Toscana Life Science, Siena, Italy.

Publikováno v: Diabetes [Diabetes] 2023 Oct 01; Vol. 72 (10), pp. 1470-1482.

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Akademický článek

High-Throughput Analysis of Neutrophil Extracellular Trap Levels in Subtypes of People with Type 1 Diabetes.

Autor: Bissenova S; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium., Buitinga M; Department of Nutrition and Movement Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, 6211 LK Maastricht, The Netherlands., Boesch M; Laboratory of Hepatology, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium., Korf H; Laboratory of Hepatology, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium., Casteels K; Woman and Child, Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium., Teunkens A; Anesthesiology and Algology, Department of Cardiovascular Sciences, KU Leuven, 3000 Leuven, Belgium., Mathieu C; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium., Gysemans C; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium.

Publikováno v: Biology [Biology (Basel)] 2023 Jun 19; Vol. 12 (6). Date of Electronic Publication: 2023 Jun 19.

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Akademický článek

NET Proteome in Established Type 1 Diabetes Is Enriched in Metabolic Proteins.

Autor: Bissenova S; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium., Ellis D; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium., Callebaut A; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium., Eelen G; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, 3000 Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, 3000 Leuven, Belgium., Derua R; Laboratory of Protein Phosphorylation & Proteomics, Department Cellular & Molecular Medicine, KU Leuven, 3000 Leuven, Belgium.; SyBioMa, Proteomics Core Facility, KU Leuven, 3000 Leuven, Belgium., Buitinga M; Department of Nutrition and Movement Sciences, Maastricht University, 6211 LK Maastricht, The Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, 6229 HX Maastricht, The Netherlands., Mathieu C; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium., Gysemans C; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium., Overbergh L; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, 3000 Leuven, Belgium.

Publikováno v: Cells [Cells] 2023 May 05; Vol. 12 (9). Date of Electronic Publication: 2023 May 05.

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Akademický článek

Neutrophils in autoimmunity: when the hero becomes the villain.

Autor: Bissenova S; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, Leuven, Belgium., Ellis D; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, Leuven, Belgium., Mathieu C; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, Leuven, Belgium., Gysemans C; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (CHROMETA), KU Leuven, Leuven, Belgium.

Publikováno v: Clinical and experimental immunology [Clin Exp Immunol] 2022 Dec 15; Vol. 210 (2), pp. 128-140.

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Akademický článek

Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice.

Autor: Sodré FMC; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Bissenova S; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Bruggeman Y; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Tilvawala R; Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA.; Department of Molecular Biosciences, The University of Kansas, Lawrence, KS., Cook DP; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Berthault C; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France., Mondal S; Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA., Callebaut A; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., You S; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France., Scharfmann R; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France., Mallone R; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France.; Assistance Publique Hôpitaux de Paris, Hôpitaux Universitaires de Paris Centre-Université de Paris, Cochin Hospital, Service de Diabétologie et Immunologie Clinique, Paris, France., Thompson PR; Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA., Mathieu C; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Buitinga M; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium., Overbergh L; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium lutgart.overbergh@kuleuven.be.

Publikováno v: Diabetes [Diabetes] 2021 Feb; Vol. 70 (2), pp. 516-528. Date of Electronic Publication: 2020 Nov 17.

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