Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Bishoy Faltas"'
Autor:
Kyle Rose, Andrea Necchi, Facundo Davaro, Elizabeth Davaro, Heather Huelster, Joseph Jacob, Grennady Bratslavsky, Dean Pavlick, Douglas Lin, Natalie Danzinger, Petros Grivas, Hikmat Al-Ahmadie, Vamsi Parimi, Philippe Spiess, Bishoy Faltas, Jeffrey Ross, Roger Li
Publikováno v:
Journal of Urology. 209
Autor:
Kenneth Wha Eng, Ellen L. Verner, David Wilkes, Kentaro Ohara, Shaham Beg, John K. Simmons, Erika Hissong, Juan Miguel Mosquera, Aanavi Karandikar, Troy Kane, Bishoy Faltas, Kevin Holcomb, Manish A. Shah, Scott T. Tagawa, Eniko Papp, Nasser K. Altorki, Michael Sigouros, Ana M. Molina, Hussein Alnajar, Emily Patchell, Wael Al Zoughbi, Cora N. Sternberg, Murtaza Malbari, Rohan Bareja, Andrea Sboner, Samuel V. Angiuoli, Yariv Houvras, Laurel Keefer, Violeta Beleva Guthrie, Noah Greco, Donna Nichol, David M. Nanus, Daniel Bockelman, Gustavo C. Cerqueira, Olivier Elemento, Jesse Fox, Jyothi Manohar
Publikováno v:
The Oncologist
Background Characterization of circulating tumor DNA (ctDNA) has been integrated into clinical practice. Although labs have standardized validation procedures to develop single locus tests, the efficacy of on‐site plasma‐based next‐generation s
Autor:
Alec Zhu, Jorge Alberto Garcia, Bishoy Faltas, Petros Grivas, Pedro Barata, Jonathan E. Shoag
Publikováno v:
JAMA Network Open. 6:e237444
This cohort study uses published clinical trial data to assess long-term survival of patients with metastatic urothelial carcinoma who are treated with immune checkpoint inhibitors.
Autor:
Sumati Gupta, Theodore Stewart Gourdin, Aaron Hardin, Petros Grivas, Lesli A. Kiedrowski, Roby Antony Thomas, Nicholas J. Vogelzang, Guru Sonpavde, Kimberly M. Hamann, Bishoy Faltas
Publikováno v:
Bladder Cancer. 7:143-148
Detecting genomic alterations (GAs) in advanced urothelial carcinoma (aUC) can expand treatment options by identifying candidates for targeted therapies. Erdafitinib is FDA-approved for patients with platinum-refractory aUC with activating mutation o
Autor:
Bishoy Faltas, Shaham Beg, David Wilkes, Kenneth Wha Eng, Brian D. Robinson, André F. Rendeiro, Aram Vosoughi, Bhavneet Bhinder, Rohan Bareja, Kyrillus S. Shohdy, Jyothi Manohar, Kentaro Ohara, Juan Miguel Mosquera, Scott T. Tagawa, David J. Pisapia, Hiranmayi Ravichandran, Olivier Elemento, Francesca Khani, Andrea Sboner, Evan Fernandez
The molecular characteristics of metastatic upper tract urothelial carcinoma (UTUC) are unknown. The genomic and transcriptomic differences between primary and metastatic UTUC is not well described either. We combined whole-exome sequencing, RNA-sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6c478970151af2e58a08548e9e1824
https://doi.org/10.1101/2021.11.16.468622
https://doi.org/10.1101/2021.11.16.468622
Autor:
Hussein, Alnajar, Hiranmayi, Ravichandran, André, Figueiredo Rendeiro, Kentaro, Ohara, Wael, Al Zoughbi, Jyothi, Manohar, Noah, Greco, Michael, Sigouros, Jesse, Fox, Emily, Muth, Samuel, Angiuoli, Bishoy, Faltas, Michael, Shusterman, Cora N, Sternberg, Olivier, Elemento, Juan Miguel, Mosquera
Publikováno v:
Cold Spring Harbor molecular case studies. 8(3)
Sarcomatoid urothelial carcinoma (SUC) is a rare subtype of urothelial carcinoma (UC) that typically presents at an advanced stage compared to more common variants of UC. Locally advanced and metastatic UC have a poor long-term survival following pro
Autor:
Juan Miguel Mosquera, Jyothi Manohar, Andrea Sboner, Michael Sigouros, Rob Kim, Bishoy Faltas, David Wilkes, Kentaro Ohara, Kenneth Eng, Princesca Dorsaint, Rohan Bareja, Olivier Elemento, Jenny Xiang, Daniel Bockelman, Alicia Alonso, Kyrillus S. Shohdy
Publikováno v:
NPJ Genomic Medicine
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
The availability of fresh frozen (FF) tissue is a barrier for implementing RNA sequencing (RNA-seq) in the clinic. The majority of clinical samples are stored as formalin-fixed, paraffin-embedded (FFPE) tissues. Exome capture platforms have been deve
Autor:
Kaylee Ho, Sarah Oh, Cristian Peña, Doron Betel, Katherine Hoffman, Erika Hissong, Uqba Khan, Arindam RoyChoudhury, Gregory F. Sonnenberg, Ashish Saxena, Manish A. Shah, Bishoy Faltas, Eun Kyeong Hwang, Kaitlin Eng Weisiger, Julianna Brouwer
Publikováno v:
American journal of clinical oncology. 44(6)
BACKGROUND Antibiotic use can result in reduced efficacy of immune checkpoint blockade (ICB), presumably because of dysbiosis of the intestinal microbiome. We sought to determine the precise temporal relation between antibiotic therapy and its possib
Autor:
Princesca Dorsaint, Robert Kim, Alicia Alonso, Olivier Elemento, Jyothi Manohar, Michael Sigouros, David Wilkes, Jenny Xiang, D. Bockelman, Andrea Sboner, Juan Miguel Mosquera, Rohan Bareja, Bishoy Faltas, Kyrillus S. Shohdy
BackgroundThe need for fresh frozen (FF) tissue limits implementing RNA sequencing (RNA-seq) in the clinic. The majority of clinical samples are processed in clinical laboratories and stored as formalin-fixed, paraffin-embedded (FFPE) tissues. Exome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dc692f223f12fb4423efa0969ea171a
https://doi.org/10.1101/2021.01.24.21250395
https://doi.org/10.1101/2021.01.24.21250395
Autor:
Michael Sigouros, Andrea Sboner, Olivier Elemento, Kenneth Wha Eng, Jyothi Manohar, Francesca Khani, Wael Al Zoughbi, Wei Zhang, Sarah Kudman, Jenny Xiang, Bishoy Faltas, Shaham Beg, David Wilkes, David J. Pisapia, Rema Rao, Cora N. Sternberg, Troy Kane, Himisha Beltran, Kentaro Ohara, Brian D. Robinson, Rohan Bareja, Juan Miguel Mosquera
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100944-(2021)
Translational Oncology
Translational Oncology
Highlights • NGS-based clinical studies have reported detection of clinically relevant alterations in ∼30% of patients. • To increase the detection of potential targets, we integrated whole-exome sequencing with a multiplex PCR-based NGS assay