Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Bishnu P De"'
Autor:
David F Havlicek, Jonathan B Rosenberg, Bishnu P De, Martin J Hicks, Dolan Sondhi, Stephen M Kaminsky, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0239780 (2020)
The cocaine vaccine dAd5GNE is comprised of a disrupted serotype 5 adenovirus gene therapy vector covalently conjugated to the cocaine analog GNE. The vaccine evokes a high titer of circulating anti-cocaine antibodies that prevent cocaine from reachi
Externí odkaz:
https://doaj.org/article/10ec18612f4b49c6a6b6e5c8dd4f8c8b
Autor:
Sandeep K. Dash, Bishnu Prasad De, Pravin K. Samanta, Bhargav Appasani, Rajib Kar, Durbadal Mandal, Nicu Bizon
Publikováno v:
Journal of Electrical and Computer Engineering, Vol 2023 (2023)
This paper deals with the optimal design of different VLSI circuits, namely, the CMOS voltage reference circuit and the CMOS ring oscillator (RO). The optimization technique used here is the multiobjective differential evolution algorithm (MDEA). All
Externí odkaz:
https://doaj.org/article/b2140ca3d82f4022af8c1086966f38a4
Autor:
Jonathan B. Rosenberg, Bishnu P. De, Alessandria Greco, Nicholas Gorman, Vikrum Kooner, Alvin Chen, Melissa Yost-Bido, Carlos Munoz-Zuluaga, Stephen M. Kaminsky, Mahboubeh Rostami, Sébastien Monette, Ronald G. Crystal, Dolan Sondhi
Publikováno v:
Human Gene Therapy. 34:139-149
α1-antitrypsin (AAT) deficiency is a common autosomal recessive hereditary disorder, with a high risk for the development of early onset panacinar emphysema. AAT produced primarily in the liver, functions to protect the lung from neutrophil protease
Autor:
Bishnu P De, Sara Cram, Hyunmi Lee, Jonathan B Rosenberg, Dolan Sondhi, Ronald G Crystal, Stephen M. Kaminsky
Publikováno v:
Human Gene Therapy.
Autor:
Carlos Munoz-Zuluaga, Monica Gertz, Melissa Yost-Bido, Alessandria Greco, Nicholas Gorman, Alvin Chen, Vikrum Kooner, Jonathan B Rosenberg, Bishnu P De, Stephen M. Kaminsky, Alain Bborczuk, Rodolfo Ricart Arbona, Heather R Martin, Sebastien Monette, Richie Khanna, Jay A Barth, Ronald G Crystal, Dolan Sondhi
Publikováno v:
Human Gene Therapy.
Publikováno v:
Journal of Electrical Systems and Information Technology, Vol 2, Iss 2, Pp 219-241 (2015)
The inverter is known to be the nucleus of all digital designs. Evolutionary computation may be a competent implement for automatic design of digital integrated circuits (IC). In this paper, optimal switching characteristics of a CMOS inverter are re
Externí odkaz:
https://doaj.org/article/8b4e4ed62ecb428194bc0049d90d6b01
Autor:
Stephen M. Kaminsky, Laith Alyass, Ronald G. Crystal, Katie M. Stiles, Bishnu P. De, Christiana Salami, Clarisse Jose, Maria J. Chiuchiolo, Dolan Sondhi, Georges-Ibrahim Cisse, Katie Jackson
Publikováno v:
Human Gene Therapy. 31:819-827
Friedreich's ataxia (FA), an autosomal recessive disorder caused by a deficiency in the expression of frataxin (FXN), is characterized by progressive ataxia and hypertrophic cardiomyopathy. Although cardiac dysfunction is the most common cause of mor
Autor:
Douglas Ballon, Jonathan B. Rosenberg, Stephen M. Kaminsky, Bishnu P. De, Dolan Sondhi, Sebastien Monette, Rodolfo J Ricart Arbona, Alvin Chen, Jonathan P. Dyke, Ronald G. Crystal
Publikováno v:
Hum Gene Ther
Metachromatic leukodystrophy, a fatal pediatric neurodegenerative lysosomal storage disease caused by mutations in the arylsulfatase A (ARSA) gene, is characterized by intracellular accumulation of sulfatides in the lysosomes of cells of the central
Autor:
Fang Xu, Kaleb Yohay, Denesy Mancenido, Mark Souwedaine, Jason G. Mezey, Douglas Ballon, Bishnu P. De, Jonathan B. Rosenberg, Michael G. Kaplitt, Grace W. Mammen, Szilard Kiss, Stephen M. Kaminsky, Odelya E. Pagovich, Ronald G. Crystal, Bruce M. Greenwald, Barry E. Kosofsky, Stefan Worgall, Benjamin Van de Graaf, Robert J. Kaner, Dolan Sondhi, Jonathan P. Dyke, Linda Heier, Neil R. Hackett, Alvin Chen
Publikováno v:
Sci Transl Med
Late infantile Batten disease (CLN2 disease) is a rare, autosomal recessive, neurodegenerative lysosomal storage disease caused by mutations in the CLN2 gene encoding tripeptidyl peptidase 1 (TPP1). We tested intraparenchymal delivery of AAVrh.10hCLN
Autor:
Stephen M. Kaminsky, Bishnu P. De, Anastasia Nikolopoulou, John W. Babich, Linda Heier, Bin He, Paul David Mozley, Alvin Chen, Jonathan B. Rosenberg, Paresh Kothari, Dolan Sondhi, Ronald G. Crystal, Douglas Ballon, Edward K Fung
Publikováno v:
Hum Gene Ther
A method is presented for quantitative analysis of the biodistribution of adeno-associated virus (AAV) gene transfer vectors following in vivo administration. We used iodine-124 (I-124) radiolabeling of the AAV capsid and positron emission tomography