Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Birthe Schubert"'
Publikováno v:
Journal of Analytical Toxicology. 43:364-368
Buprenorphine is a commonly used opioid in pain therapy as well as in opiate maintenance therapy. Immunoassays are quick and cost-effective methods for the necessary toxicological urine analysis of maintenance therapy patients. In this study a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeea4e63bfcccdf539b5639c9e118cb1
https://doi.org/10.1093/jat/bkz003
https://doi.org/10.1093/jat/bkz003
Publikováno v:
Journal of analytical toxicology. 45(9)
Buprenorphine is a semisynthetic opioid that is often used in opiate maintenance therapy. For this purpose, regular toxicological analyses of urine samples are mandatory. For fast analytical results, analyses are commonly performed by immunoassay, fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2daec4a1a94de8a40caf741f8b77912d
https://pubmed.ncbi.nlm.nih.gov/33104778
https://pubmed.ncbi.nlm.nih.gov/33104778
Publikováno v:
Analytica Chimica Acta. 770:121-131
Systematic toxicological analysis (STA) is aimed at detecting and identifying all substances of toxicological relevance (i.e. drugs, drugs of abuse, poisons and/or their metabolites) in biological material. Particularly, gas chromatography-mass spect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ae45f9a4254d147a208174c67655e9
https://doi.org/10.1016/j.aca.2013.01.057
https://doi.org/10.1016/j.aca.2013.01.057
Autor:
Herbert Oberacher, Birthe Schubert
Publikováno v:
Journal of Chromatography A. 1218:3413-3422
In this study the impact of solvent conditions on the performance of μLC/MS for the analysis of basic drugs was investigated. Our aim was to find experimental conditions that enable high-performance chromatographic separation particularly at overloa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8081fab914595a40556fdea5b66f4c3
https://doi.org/10.1016/j.chroma.2011.03.051
https://doi.org/10.1016/j.chroma.2011.03.051
Autor:
Michael Hubalek, Verena Meraner, Anne Oberguggenberger, B Holzner, Birthe Schubert, Herbert Oberacher, B Beer
Publikováno v:
Cancer Research. 70:P5-11
Background: Clinical data have repeatedly shown that tamoxifen as well as anastrazole and letrozole significantly increase the overall survival among breast cancer patients. However, in several cases the use of these drugs is limited by side effects,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba69e74cbc1822fed2eebdb95a025aa9
https://doi.org/10.1158/0008-5472.sabcs10-p5-11-09
https://doi.org/10.1158/0008-5472.sabcs10-p5-11-09
Autor:
Birthe Schubert, Anne Oberguggenberger, Michael Hubalek, Verena Meraner, B Beer, Barbara Sperner-Unterweger, Herbert Oberacher
Publikováno v:
Cancer Research. 70:P5-11
Background: Personalized medicine strategies are especially relevant for drugs which show a high inter-individual variability regarding their pharmacokinetic and -dynamic properties. Considerable inter-patient variations have been described regarding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4917a4a4472bfb8830ceace414973dd1
https://doi.org/10.1158/0008-5472.sabcs10-p5-11-04
https://doi.org/10.1158/0008-5472.sabcs10-p5-11-04
Autor:
Birthe Schubert, Verena Meraner, Herbert Oberacher, B Beer, Michael Hubalek, Anne Oberguggenberger
Publikováno v:
Analytical and Bioanalytical Chemistry. 398:1791-1800
There is substantial evidence that circulating estrogens promote the proliferation of breast cancer. Consequently, adjuvant hormonal treatment strategies targeting estrogen action have been established. Such hormonal therapies include selective estro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c092b20a45e9714d93b009393eb3bd8
https://doi.org/10.1007/s00216-010-4075-z
https://doi.org/10.1007/s00216-010-4075-z
Publikováno v:
Forensic Science International. 197:40-47
A convenient mass spectrometric approach for the identification of toxicologically relevant compounds in tablets and tablet residues is presented. For comprehensive forensic-toxicological analysis electrospray ionization mass spectrometry was accompl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6016efd83fd154e69e270c05dca6ef96
https://doi.org/10.1016/j.forsciint.2009.12.019
https://doi.org/10.1016/j.forsciint.2009.12.019
Publikováno v:
Journal of Chromatography A. 1216:3192-3198
During the last 2 years, the knowledge on the metabolic pathway of tetrazepam, a muscle relaxant drug, was expanded by the fact that diazepam was identified as a degradation product of tetrazepam. The present study demonstrates that this metabolic co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53655098fa9fbdbc69565114497d338b
https://doi.org/10.1016/j.chroma.2009.02.001
https://doi.org/10.1016/j.chroma.2009.02.001
Autor:
Marion Pavlic, Harald Köfeler, Edina Csaszar, Rainer Schuhmacher, Kathrin Libiseller, Birthe Schubert, Herbert Oberacher, Michael Sulyok
Publikováno v:
Journal of Mass Spectrometry. 44:485-493
The inter-instrument and inter-laboratory transferability of a tandem mass spectral reference library originally built on a quadrupole-quadrupole-time-of-flight instrument was examined. The library consisted of 3759 MS/MS spectra collected from 402 r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fbd81e3f28098be5bf850f76353a967
https://doi.org/10.1002/jms.1545
https://doi.org/10.1002/jms.1545