Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Birthe Lohmann"'
Autor:
Birthe Lohmann, Guido Reifenberger, Daniel Picard, Michael Weller, Hannah Schneider, Manuela Silginer, Patrick Roth, Marc Remke
Publikováno v:
Neuro-oncology Advances
BackgroundType I interferons (IFN-α/β) are cytokines that are typically expressed in response to double-stranded RNA associated with viral infections. Glioblastomas are the most common malignant primary brain tumors, characterized by an infiltrativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54bd97c6cd15c9d6d29beacee0f456c
https://pubmed.ncbi.nlm.nih.gov/32642697
https://pubmed.ncbi.nlm.nih.gov/32642697
Publikováno v:
Oncology Letters
Oncology Letters, 2020, Oncology Letters, 19, pp.2649-2656. ⟨10.3892/ol.2020.11362⟩
Oncology Letters, 2020, Oncology Letters, 19, pp.2649-2656. ⟨10.3892/ol.2020.11362⟩
International audience; Novel treatments for glioblastoma, the most common malignant primary brain tumor, are urgently required. Type I interferons (IFN) are natural cytokines primarily involved in the defense against viral infections, which may also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba4570338aeae886bca3953c7ac93d9
https://doi.org/10.3892/ol.2020.11362
https://doi.org/10.3892/ol.2020.11362
Autor:
Martin Pruschy, Hannah Schneider, Elisabeth J. Rushing, Michael Weller, Kathy Hasenbach, Karl Frei, Birthe Lohmann, Ghazaleh Tabatabai, Hans-Georg Wirsching
Publikováno v:
Oncotarget
// Hannah Schneider 1 , Birthe Lohmann 1 , Hans-Georg Wirsching 1 , Kathy Hasenbach 1 , Elisabeth J. Rushing 3 , Karl Frei 2, 4 , Martin Pruschy 5 , Ghazaleh Tabatabai 1, * and Michael Weller 1, 2 1 Laboratory of Molecular Neuro-Oncology, Department
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca57a7461b6965b4a8c610b3ce34cb81
https://doi.org/10.18632/oncotarget.19894
https://doi.org/10.18632/oncotarget.19894
Publikováno v:
Neuro Oncol
Novel treatments for glioblastoma, the most common malignant primary brain tumor, are urgently needed. Type I interferons (IFN) are natural cytokines primarily involved in defense against viral infections, but may also play a role in the control of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9b3997792820302706716f811a1c58
https://europepmc.org/articles/PMC6847935/
https://europepmc.org/articles/PMC6847935/
Autor:
Hannah Schneider, Caroline von Achenbach, Emese Szabo, Michael Weller, Birthe Lohmann, Emilie Le Rhun, Manuela Silginer, Kristan Meetze
Publikováno v:
International Journal of Cancer
International Journal of Cancer, Wiley, 2019, 145 (1), pp.242-253. ⟨10.1002/ijc.32069⟩
International Journal of Cancer, Wiley, 2019, 145 (1), pp.242-253. ⟨10.1002/ijc.32069⟩
International audience; TG02 is a novel cyclin-dependent kinase (CDK) inhibitor and thought to act mainly via CDK-9 inhibition-dependent depletion of short-lived oncoproteins such as MCL-1 or c-MYC. We studied the activity of TG02 in 9 human long-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114a775717811f157387e7d5249be5ec
https://www.hal.inserm.fr/inserm-02941519/file/ijc.32069.pdf
https://www.hal.inserm.fr/inserm-02941519/file/ijc.32069.pdf
Autor:
Michael Weller, E Le Rhun, Manuela Silginer, Birthe Lohmann, Emese Szabo, Hannah Schneider, K Meetze, C von Achenbach
Publikováno v:
Europe PubMed Central
BACKGROUND: TG02 is a novel multikinase inhibitor targeting cyclin-dependent kinases (CDK) -1, -2, -5, -7 and -9 and thought to act mainly via CDK-9 inhibition-dependent depletion of short-lived oncoproteins such as MCL-1 or c-MYC. MATERIAL AND METHO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55dd18dfa201e70b3ef22960b0526f70
https://doi.org/10.1093/neuonc/noy139.245
https://doi.org/10.1093/neuonc/noy139.245
Autor:
Birthe Lohmann, Hannah Schneider
Publikováno v:
Neuro-Oncology. 19:iii65-iii65
The poor prognosis associated with advanced age in patients with glioblastoma remains poorly understood. Glioblastoma in the elderly has been particularly associated with vascular endothelial growth factor (VEGF)-dependent angiogenesis, with anti-ang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f26f9ce6da146c96ddf122d923f2a9
https://doi.org/10.1093/neuonc/nox036.240
https://doi.org/10.1093/neuonc/nox036.240
Autor:
Hans-Peter Hartung, Jan-philipp Weinberger, Anne K. Mausberg, Bernd C. Kieseier, Birthe Lohmann, Thomas Dehmel, Mark Stettner, Kathleen Wolffram
Publikováno v:
Journal of Neuroinflammation
Background Pro-inflammatory cytokines are known to have deleterious effects on Schwann cells (SCs). Interleukin 17 (IL-17) is a potent pro-inflammatory cytokine that exhibits relevant effects during inflammation in the peripheral nervous system (PNS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e6ffbb79bd29e476b58d894b28cb22
http://europepmc.org/articles/PMC3977670
http://europepmc.org/articles/PMC3977670