Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Birthe Kann"'
Autor:
Karine Coradini, Herman L. Offerhaus, Rossana B. Friedrich, Birthe Kann, Ruy Carlos Ruver Beck, Maike Windbergs
Publikováno v:
European journal of pharmaceutical sciences, 78:3328, 204-213. Elsevier
Polyphenols, which are secondary plant metabolites, gain increasing research interest due to their therapeutic potential. Among them, resveratrol and curcumin are two agents showing antioxidant, anti-inflammatory, antimicrobial as well as anticarcino
Publikováno v:
Advanced Drug Delivery Reviews. 89:71-90
Progress in advanced therapeutic concepts requires the development of appropriate carrier systems for intracellular drug delivery. Consequently, analysis of interaction between carriers, drugs and cells as well as their uptake and intracellular fate
Autor:
Birthe Kann, M Hainschitz, Eva Roblegg, Simone Schrank, Johannes Khinast, Maike Windbergs, Eva-Maria Saurugger, Benjamin J. Glasser
Publikováno v:
International Journal of Pharmaceutics. 478:779-787
Although drying is widely applied during the manufacturing of solid dosage forms, its potential effect on the product’s (key) properties is often underestimated. Hence, the present study addresses drying related modifications of wet-extruded pellet
Autor:
Harald Berchtold, Maike Windbergs, Claus-Michael Lehr, Thomas Eichinger, Stefan Balbach, Petra Loos, Ulrich F. Schaefer, Birthe Kann, Sandra P. Gantzsch, Monika Ofer-Glaessgen
Publikováno v:
Journal of Controlled Release. 175:79-86
Aim of this study was to implement a modified phospholipid vesicle-based permeation assay (PVPA) barrier as alternative to Caco-2 cell monolayers in a combined dissolution and permeation system for testing of solid dosage forms. Commercially availabl
Autor:
Lucas Almeida Rigo, Maike Windbergs, Christian Spengler, Herman L. Offerhaus, Birthe Kann, Ruy Carlos Ruver Beck, Karine Coradini, Martin L. Bennink, Karin Jacobs
Publikováno v:
Analytical chemistry, 88(14), 7014-7022. American Chemical Society
Increased molecular understanding of multifactorial diseases paves the way for novel therapeutic approaches requiring sophisticated carriers for intracellular delivery of actives. We designed and characterized self-assembling lipid-core nanocapsules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561bef7179118073d4ff6b5af65b3ae0
https://research.utwente.nl/en/publications/fb495dca-3189-4c35-a0b1-ef54d28655f9
https://research.utwente.nl/en/publications/fb495dca-3189-4c35-a0b1-ef54d28655f9
Publikováno v:
The Analyst. 139(20)
In this study, we present confocal Raman microscopy for chemically selective analysis of a human buccal epithelial cell layer with a focus on label-free visualization of particle uptake into the cells. We demonstrate the suitability and benefit of th
Autor:
T.C. Beber, Ruy Carlos Ruver Beck, Diego Fontana de Andrade, M C Fontana, Maike Windbergs, Karine Coradini, Birthe Kann
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 88(3)
Topical glucocorticoids (TG) such as dexamethasone (DEX) have been used for decades for the treatment of skin diseases. However, TG present well-documented side effects and their delivery to the skin is often insufficient. Therefore, many efforts hav
Autor:
Andreas Zimmer, Eva Roblegg, Simone Schrank, Benjamin J. Glasser, Eva-Maria Saurugger, Maike Windbergs, Johannes Khinast, Heike M. A. Ehmann, Oliver Werzer, Birthe Kann
Publikováno v:
Molecular pharmaceutics. 11(2)
Drying is a common pharmaceutical process, whose potential to alter the final drug properties—even at relatively low temperatures—is often neglected. The present study addresses the impact of drying at 20 and 50 °C on wet-extruded calcium steara
Publikováno v:
Journal of pharmaceutical sciences. 102(11)
Embedding a poorly water-soluble drug as a solid dispersion in a hydrophilic carrier by cogrinding is a possible strategy for enhancing the drug dissolution rate. Although general interest in continuous processes for manufacturing drug formulations h
Autor:
Eva Roblegg, Simone Schrank, Johannes Khinast, Birthe Kann, Andreas Zimmer, Benjamin J. Glasser, Maike Windbergs
Publikováno v:
Journal of pharmaceutical sciences. 102(11)
Drying is a common pharmaceutical process, whose potential to modify the final drug and/or dosage form properties is often underestimated. In the present study, pellets consisting of the matrix former calcium stearate (CaSt) incorporating the active