Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Birte Jeiler"'
Autor:
Nadine Weinelt, Kaja Nicole Wächtershäuser, Gulustan Celik, Birte Jeiler, Isabelle Gollin, Laura Zein, Sonja Smith, Geoffroy Andrieux, Tonmoy Das, Jens Roedig, Leonard Feist, Björn Rotter, Melanie Boerries, Francesco Pampaloni, Sjoerd J. L. van Wijk
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Plasma membrane accumulation of phosphorylated mixed lineage kinase domain-like (MLKL) is a hallmark of necroptosis, leading to membrane rupture and inflammatory cell death. Pro-death functions of MLKL are tightly controlled by several check
Externí odkaz:
https://doaj.org/article/e14e541c4820493ea444b18cd9044345
Autor:
Annkathrin Koch, Birte Jeiler, Jens Roedig, Sjoerd J.L. van Wijk, Nadezda Dolgikh, Simone Fulda
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 539-550 (2021)
Burkitt's lymphoma (BL) is a highly aggressive form of B-cell non-Hodgkin's lymphoma. The clinical outcome in children with BL has improved over the last years but the prognosis for adults is still poor, highlighting the need for novel treatment stra
Externí odkaz:
https://doaj.org/article/746d29e524ac4212a6dfac6ce63571a4
Autor:
Wolfgang Hartmann, Sebastian Huss, Eva Wardelmann, Pierre Åman, Jessica Becker, Thomas Simmet, Susanne Hafner, Claudia Rossig, Bianca Altvater, Konrad Steinestel, Inga Grünewald, Arne Krüger, Birte Jeiler, Ilka Isfort, Magdalene Cyra, Marcel Trautmann
Myxoid liposarcoma (MLS) is an aggressive soft-tissue tumor characterized by a specific reciprocal t(12;16) translocation resulting in expression of the chimeric FUS–DDIT3 fusion protein, an oncogenic transcription factor. Similar to other transloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e2be92ae79f97e822effef90988d24b
https://doi.org/10.1158/1535-7163.c.6537922.v1
https://doi.org/10.1158/1535-7163.c.6537922.v1
Autor:
Wolfgang Hartmann, Sebastian Huss, Eva Wardelmann, Pierre Åman, Jessica Becker, Thomas Simmet, Susanne Hafner, Claudia Rossig, Bianca Altvater, Konrad Steinestel, Inga Grünewald, Arne Krüger, Birte Jeiler, Ilka Isfort, Magdalene Cyra, Marcel Trautmann
Supplementary Table S1: Clinicopathological characteristics of patients with myxoid liposarcoma (n=56) including semi-quantitative immunohistochemistry and mutational analyses results. Supplemental Table S2: Gene list. Supplementary Table S3: In sili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28395882e925867546c8eef441fd1d0c
https://doi.org/10.1158/1535-7163.22504987.v1
https://doi.org/10.1158/1535-7163.22504987.v1
Autor:
Wolfgang Hartmann, Sebastian Huss, Eva Wardelmann, Pierre Åman, Jessica Becker, Thomas Simmet, Susanne Hafner, Claudia Rossig, Bianca Altvater, Konrad Steinestel, Inga Grünewald, Arne Krüger, Birte Jeiler, Ilka Isfort, Magdalene Cyra, Marcel Trautmann
Supplementary Figure S1: In vitro and in vivo evaluation of PI3K suppression (LY294002) in myxoid liposarcoma cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c5f6c811e6ff156e3fe58abe446ae2
https://doi.org/10.1158/1535-7163.22504996.v1
https://doi.org/10.1158/1535-7163.22504996.v1
Autor:
Nadine Weinelt, Kaja Nicole Wächtershäuser, Sonja Smith, Geoffroy Andrieux, Tonmoy Das, Birte Jeiler, Jens Roedig, Leonard Feist, Björn Rotter, Melanie Boerries, Francesco Pampaloni, Sjoerd J. L. van Wijk
SummaryPlasma membrane accumulation of phosphorylated mixed lineage kinase domain-like (MLKL) is a hallmark of necroptosis, leading to membrane rupture and inflammatory cell death. Pro-death functions of MLKL are tightly controlled by several checkpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4828c0934cdfab986bcf7f630ce0d9c1
https://doi.org/10.1101/2022.12.08.519265
https://doi.org/10.1101/2022.12.08.519265
Autor:
Sebastian Huss, Pierre Åman, Bianca Altvater, Arne Krüger, Thomas Simmet, Claudia Rossig, Eva Wardelmann, Konrad Steinestel, Susanne Hafner, Wolfgang Hartmann, Ilka Isfort, Jessica Becker, Marcel Trautmann, Inga Grünewald, Magdalene Cyra, Birte Jeiler
Publikováno v:
Molecular Cancer Therapeutics. 18:834-844
Myxoid liposarcoma (MLS) is an aggressive soft-tissue tumor characterized by a specific reciprocal t(12;16) translocation resulting in expression of the chimeric FUS–DDIT3 fusion protein, an oncogenic transcription factor. Similar to other transloc
Autor:
Sjoerd J L van Wijk, Simone Fulda, Birte Jeiler, Jens Roedig, Nadezda Dolgikh, Annkathrin Koch
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 539-550 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 539-550 (2021)
Burkitt's lymphoma (BL) is a highly aggressive form of B-cell non-Hodgkin's lymphoma. The clinical outcome in children with BL has improved over the last years but the prognosis for adults is still poor, highlighting the need for novel treatment stra
Autor:
Sebastian Huss, Georg Gosheger, Wolfgang Hartmann, Jan Rehkämper, Eva Wardelmann, Elena Hekeler, Birte Jeiler, Daniel Baumhoer, Arne Streitbürger, Sandra Elges, Konrad Steinestel, Jendrik Hardes, Marcel Trautmann, Jan Sperveslage
Publikováno v:
Oncotarget
The diagnosis of giant cell-rich lesions of bone can be challenging if radiological findings are ambiguous and tissue of the biologically deciding component is underrepresented in biopsy specimens. The frequent association of giant cell tumor of bone
Autor:
Sebastian Huss, Eva Wardelmann, Inga Grünewald, Christian Bertling, Magdalene Cyra, Arne Krüger, Wolfgang Hartmann, Pierre Åman, Marcel Trautmann, Jasmin Menzel, Konrad Steinestel, Birte Jeiler
Publikováno v:
Cancer Research. 77:B05-B05
Introduction: Myxoid liposarcoma (MLS) is the second most common type of liposarcoma, accounting for 30-35% of all LS cases. Over 90% of tumors are characterized by a reciprocal translocation t (12; 16) (q13; p11), resulting in a pathogenic gene fusi