Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Birte Albrecht"'
Autor:
Stephan Menzel, Yinghui Duan, Julia Hambach, Birte Albrecht, Dorte Wendt-Cousin, Riekje Winzer, Eva Tolosa, Anne Rissiek, Andreas H. Guse, Friedrich Haag, Tim Magnus, Friedrich Koch-Nolte, Björn Rissiek
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
CD39 is the major enzyme controlling the levels of extracellular adenosine triphosphate (ATP) via the stepwise hydrolysis of ATP to adenosine diphosphate (ADP) and adenosine monophosphate (AMP). As extracellular ATP is a strong promoter of inflammati
Externí odkaz:
https://doaj.org/article/ede936c25e8b4acd80c5bcc8d2044e79
Autor:
Anna Marei Eichhoff, Kathleen Börner, Birte Albrecht, Waldemar Schäfer, Natalie Baum, Friedrich Haag, Jakob Körbelin, Martin Trepel, Ingke Braren, Dirk Grimm, Sahil Adriouch, Friedrich Koch-Nolte
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss , Pp 211-220 (2019)
A limiting factor for the use of adeno-associated viruses (AAVs) as vectors in gene therapy is the broad tropism of AAV serotypes, i.e., the parallel infection of several cell types. Nanobodies are single immunoglobulin variable domains from heavy ch
Externí odkaz:
https://doaj.org/article/dba14e69bc8b42e19b8f68057c149779
Autor:
Kerstin Schütze, Katharina Petry, Julia Hambach, Niklas Schuster, William Fumey, Levin Schriewer, Jana Röckendorf, Stephan Menzel, Birte Albrecht, Friedrich Haag, Catelijne Stortelers, Peter Bannas, Friedrich Koch-Nolte
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
CD38 is overexpressed by multiple myeloma cells and has emerged as a target for therapeutic antibodies. Nanobodies are soluble single domain antibody fragments derived from the VHH variable domain of heavy chain antibodies naturally occurring in came
Externí odkaz:
https://doaj.org/article/73386a564c9a465d8f987c717ce73431
Autor:
Julia Hambach, Kristoffer Riecken, Sophia Cichutek, Kerstin Schütze, Birte Albrecht, Katharina Petry, Jana Larissa Röckendorf, Natalie Baum, Nicolaus Kröger, Timon Hansen, Gunter Schuch, Friedrich Haag, Gerhard Adam, Boris Fehse, Peter Bannas, Friedrich Koch-Nolte
Publikováno v:
Cells, Vol 9, Iss 2, p 321 (2020)
The NAD-hydrolyzing ecto-enzyme CD38 is overexpressed by multiple myeloma and other hematological malignancies. We recently generated CD38-specific nanobodies, single immunoglobulin variable domains derived from heavy-chain antibodies naturally occur
Externí odkaz:
https://doaj.org/article/45aa97fe88f54d0990491ef3c162f04d
A cDNA Immunization Strategy to Generate Nanobodies against Membrane Proteins in Native Conformation
Autor:
Thomas Eden, Stephan Menzel, Janusz Wesolowski, Philine Bergmann, Marion Nissen, Gudrun Dubberke, Fabienne Seyfried, Birte Albrecht, Friedrich Haag, Friedrich Koch-Nolte
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Nanobodies (Nbs) are soluble, versatile, single-domain binding modules derived from the VHH variable domain of heavy-chain antibodies naturally occurring in camelids. Nbs hold huge promise as novel therapeutic biologics. Membrane proteins are among t
Externí odkaz:
https://doaj.org/article/f32d53944d1d4dfdb3c246d77c599d57
Autor:
Natalie Baum, Kathleen Börner, Friedrich Koch-Nolte, Friedrich Haag, Martin Trepel, Anna Marei Eichhoff, Sahil Adriouch, Ingke Braren, Birte Albrecht, Jakob Körbelin, Dirk Grimm, Waldemar Schäfer
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy-Methods and Clinical Development
Molecular Therapy-Methods and Clinical Development, Nature Publishing Group, 2019, 15, pp.211-220. ⟨10.1016/j.omtm.2019.09.003⟩
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss, Pp 211-220 (2019)
Molecular Therapy-Methods and Clinical Development
Molecular Therapy-Methods and Clinical Development, Nature Publishing Group, 2019, 15, pp.211-220. ⟨10.1016/j.omtm.2019.09.003⟩
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss, Pp 211-220 (2019)
A limiting factor for the use of adeno-associated viruses (AAVs) as vectors in gene therapy is the broad tropism of AAV serotypes, i.e., the parallel infection of several cell types. Nanobodies are single immunoglobulin variable domains from heavy ch
Background Men are exposed to different health risks than women. For instance, older men have an increased risk of social isolation. At the same time, they are less likely to participate in health promotion interventions and there is a lack of men-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15409dfe24428ad2165bf8b0883141e2
https://doi.org/10.21203/rs.3.rs-118163/v1
https://doi.org/10.21203/rs.3.rs-118163/v1
Autor:
Peter Bannas, Timon Hansen, Nicolaus Kröger, Björn Rissiek, Katharina Petry, Friedrich Koch-Nolte, Mascha Binder, Boris Fehse, Julia Koenigsdorf, Levin Schriewer, Birte Albrecht, William Fumey, Jana Larissa Röckendorf, Francis Ayuk, Kerstin Schütze, Gunter Schuch, Friedrich Haag, Stephan Menzel, Gerhard Adam, Hans O. Pinnschmidt, Kristoffer Riecken, Joanna Schmid, Natalie Baum, Julia Hambach
Publikováno v:
Theranostics
Rationale: CD38 is a target for the therapy of multiple myeloma (MM) with monoclonal antibodies such as daratumumab and isatuximab. Since MM patients exhibit a high rate of relapse, the development of new biologics targeting alternative CD38 epitopes
A cDNA Immunization Strategy to Generate Nanobodies against Membrane Proteins in Native Conformation
Autor:
Philine Bergmann, Marion Nissen, Friedrich Koch-Nolte, Gudrun Dubberke, Thomas Eden, Janusz Wesolowski, Fabienne Seyfried, Birte Albrecht, Stephan Menzel, Friedrich Haag
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Frontiers in Immunology
Frontiers in Immunology
Nanobodies are soluble, versatile, single-domain binding modules derived from the VHH variable domain of heavy chain antibodies naturally occurring in camelids. Nanobodies hold huge promise as novel therapeutic biologics. Membrane proteins are among