Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Birte Aggeler"'
Autor:
Carl A Ascoli, Birte Aggeler
Publikováno v:
BioTechniques, Vol 65, Iss 3, Pp 127-136 (2018)
The benefits of polyclonal antibodies as tools for assay-specific target discovery and detection are numerous. As the future of basic research, diagnostics and biomarker discovery is dependent on high-quality reproducible data, there is a need to und
Externí odkaz:
https://doaj.org/article/5f521ee840094debbaf32a92760c7404
Autor:
Louis Leong, Benjamin Tehan, Dean G. Brown, Dawn M. Troast, Giles A. Brown, Nils-Olov Hermansson, Peter E. Thornton, Cédric Fiez-Vandal, Holly H. Soutter, Oliver Schlenker, Fiona H. Marshall, Robert M. Cooke, Arjan Snijder, Karl Edman, Christoph Grebner, Giselle R. Wiggin, A.S. Dore, Stefan Geschwindner, Andrei Zhukov, Birte Aggeler, Christoph E. Dumelin, Niek Dekker, Patrik Johansson, Robert K. Y. Cheng, Mathieu Rappas, Ali Jazayeri, Linda Sundström, Rudi Prihandoko
Publikováno v:
Nature. 545:112-115
Crystal structures of protease-activated receptor 2 (PAR2) in complex with two different antagonist ligands and with a blocking antibody reveal binding sites that are distinct from those found on PAR1, offering new leads for structure-based drug desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ed03d801965b48c5792271544c4222
https://doi.org/10.1038/nature22309
https://doi.org/10.1038/nature22309
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1644
DNA can be damaged by many environmental factors including chemical agents and ionizing radiation which induce the formation of DNA double-stranded breaks (DSBs). If DSBs are not repaired in a timely fashion this may cause the disruption of genome in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ade0151b1c3682e5dfad91565cf85752
https://pubmed.ncbi.nlm.nih.gov/28710758
https://pubmed.ncbi.nlm.nih.gov/28710758
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1554
Flow cytometry is a powerful technique that allows simultaneous detection of multiple markers on a specific cell population. This method is virtually unlimited as long as the specimen of interest can be put into a single-cell suspension for staining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b14f47d6f0bc3f0371383e6ee6b6035
https://pubmed.ncbi.nlm.nih.gov/28185190
https://pubmed.ncbi.nlm.nih.gov/28185190
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1554
Due to their inherent nature, DNA strands can be easily broken by various environmental factors including chemical agents and ionizing radiation. Unrepaired DNA double-stranded breaks (DSBs) may result in genetic instability and have a strong negativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be8203759aa37ebb0951f75e15e45fc8
https://pubmed.ncbi.nlm.nih.gov/28185200
https://pubmed.ncbi.nlm.nih.gov/28185200
Publikováno v:
Methods in Molecular Biology ISBN: 9781493967575
Due to their inherent nature, DNA strands can be easily broken by various environmental factors including chemical agents and ionizing radiation. Unrepaired DNA double-stranded breaks (DSBs) may result in genetic instability and have a strong negativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c1708e5b372b4cd8aaffc26e59b29e6
https://doi.org/10.1007/978-1-4939-6759-9_20
https://doi.org/10.1007/978-1-4939-6759-9_20
Publikováno v:
Methods in Molecular Biology ISBN: 9781493967575
Flow cytometry is a powerful technique that allows simultaneous detection of multiple markers on a specific cell population. This method is virtually unlimited as long as the specimen of interest can be put into a single-cell suspension for staining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfd700cbc33685d40718212cc275e531
https://doi.org/10.1007/978-1-4939-6759-9_10
https://doi.org/10.1007/978-1-4939-6759-9_10
Publikováno v:
Fast Detection of DNA Damage ISBN: 9781493971855
DNA can be damaged by many environmental factors including chemical agents and ionizing radiation which induce the formation of DNA double-stranded breaks (DSBs). If DSBs are not repaired in a timely fashion this may cause the disruption of genome in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e758efe69a26657be60145132a6e3271
https://doi.org/10.1007/978-1-4939-7187-9_10
https://doi.org/10.1007/978-1-4939-7187-9_10
Publikováno v:
The Journal of Immunology. 198:138.7-138.7
Macrophages are ubiquitously distributed throughout the various tissues of the body and perform many functions. These include inflammatory responses against pathogens by classically activated M1 macrophages and the regulation of wound healing and tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f8ab95e36b0b04764a6b3ffb45f3a13
https://doi.org/10.4049/jimmunol.198.supp.138.7
https://doi.org/10.4049/jimmunol.198.supp.138.7
Autor:
Birte Aggeler, Paul Waring, Katerina Dvorak, Penny McKelvie, John Palting, Andrew Ruszkiewicz
Publikováno v:
Pathology
Summary The most common of all activating BRAF mutations (T1799A) leads to a substitution of valine (V) to glutamic acid (E) at the position 600 of the amino acid sequence. The major goal of this study was to compare detection of the BRAF V600E mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83bc5d9902291671c9f994951a4139e
https://hdl.handle.net/1959.8/161294
https://hdl.handle.net/1959.8/161294