Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Birte, Drewes"'
Autor:
Boris D. Zlatopolskiy, Felix Neumaier, Till Rüngeler, Birte Drewes, Niklas Kolks, Bernd Neumaier
Publikováno v:
Molecules, Vol 25, Iss 12, p 2880 (2020)
M1 muscarinic acetylcholine receptors (mAChRs) are abundant in postsynaptic nerve terminals of all forebrain regions and have been implicated in the cognitive decline associated with Alzheimer’s disease and other CNS pathologies. Consequently, majo
Externí odkaz:
https://doaj.org/article/601a7baf02da4c3c892d1c769490d6fc
Autor:
Felix Neumaier, Annette Schulze, Birte Drewes, Wiebke Sihver, Dirk Bier, Franziska Wedekind, Marcus H. Holschbach, Bernd Neumaier, Andreas Bauer
Publikováno v:
Journal of radioanalytical and nuclear chemistry 326(3), 1691-1697 (2020). doi:10.1007/s10967-020-07465-2
5-Iodotubercidin is a prototype adenosine kinase (AK) inhibitor with potent anti-seizure activity in rodent epilepsy models. Using the chloramine-T method for radioiodination of tubercidin with 131I, we prepared no-carrier-added 5-[131I]iodotubercidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63bb9cabbd3e0e4c3c651b8ca5adde62
https://doi.org/10.1007/s10967-020-07465-2
https://doi.org/10.1007/s10967-020-07465-2
Autor:
Nils Walter, Jan Bertram, Birte Drewes, Victor Bahutski, Marco Timmer, Markus B. Schütz, Felicia Krämer, Felix Neumaier, Heike Endepols, Bernd Neumaier, Boris D. Zlatopolskiy
Publikováno v:
European journal of medicinal chemistry 237, 114383 (2022). doi:10.1016/j.ejmech.2022.114383
Recently, a protocol for radiolabeling of aryl fluorosulfates (“SuFEx click radiolabeling”) using ultrafast18F/19F isotopic exchange has been reported. Although promising, the original procedure turned out to berather inefficient. However, system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8a8681c745efda5edcca5b1a1c69c6
https://hdl.handle.net/2128/31129
https://hdl.handle.net/2128/31129
Autor:
Nils, Walter, Jan, Bertram, Birte, Drewes, Victor, Bahutski, Marco, Timmer, Markus B, Schütz, Felicia, Krämer, Felix, Neumaier, Heike, Endepols, Bernd, Neumaier, Boris D, Zlatopolskiy
Publikováno v:
European journal of medicinal chemistry. 237
Recently, a protocol for radiolabeling of aryl fluorosulfates ("SuFEx click radiolabeling") using ultrafast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14e3cf08e6159c41643c46be58ddd4d9
https://pubmed.ncbi.nlm.nih.gov/35447431
https://pubmed.ncbi.nlm.nih.gov/35447431
Autor:
Ulrich Flörke, Birte Drewes
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 11, Pp o1646-o1647 (2013)
The molecular structure of the title compound, C11H13IN4O3, shows a ribofuranosyl–pyrrolo O—C—N—C torsion angle of 59.1 (3)°, with the central C—N bond length being 1.446 (3) Å. The C—I bond length is 2.072 (2) Å. The amino group is co
Externí odkaz:
https://doaj.org/article/61a0b9aa7a0b4a09b3de731484651b9c
Publikováno v:
Nuclear Medicine and Biology. 34:531-539
Positron emission tomography (PET) imaging of dopamine transporter (DAT) density in the brain is a potentially valuable tool for studying the etiopathology of degenerative brain disorders. The present study evaluated five new potential competitive in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9b5a0ff7c64d1d8dfd44af3e766e03
https://doi.org/10.1016/j.nucmedbio.2007.04.007
https://doi.org/10.1016/j.nucmedbio.2007.04.007
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 50:1169-1175
Arylpropylsulphonamides are in the focus of research as α-amino-3-hydroxy-5-methyl-4-isoxazolpropionic acid (AMPA) receptor ligands. A new fluorine-18-labelled potentiator of AMPA receptors was synthesized as a potential radiotracer for cerebral ima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::932c855c8262304539ec0c555f3a6046
https://doi.org/10.1002/jlcr.1413
https://doi.org/10.1002/jlcr.1413
Autor:
Ulrich Flörke, Birte Drewes
Publikováno v:
Acta Crystallographica Section E: Structure Reports
Acta crystallographica / E E69, 01646-01647 (2013). doi:10.1107/S1600536813027931
Acta Crystallographica Section E, Vol 69, Iss 11, Pp o1646-o1647 (2013)
Acta crystallographica / E E69, 01646-01647 (2013). doi:10.1107/S1600536813027931
Acta Crystallographica Section E, Vol 69, Iss 11, Pp o1646-o1647 (2013)
The molecular structure of the title compound, C11H13IN4O3, shows a ribofuranosyl–pyrrolo O—C—N—C torsion angle of 59.1 (3)°, with the central C—N bond length being 1.446 (3) Å. The C—I bond length is 2.072 (2) Å. The amino group is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8558dabf9cf91149ebfa0f141a11cfd
https://pubmed.ncbi.nlm.nih.gov/24454089
https://pubmed.ncbi.nlm.nih.gov/24454089
Publikováno v:
Nuclear medicine and biology. 34(2)
This study evaluated novel potential dopamine transporter (DAT) inhibitors as ligands for positron emission tomography. Five new tropane analogs were synthesized and compared with the known ligand 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane (beta-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d26ae42102aefe76f7b2a47967cb951
https://pubmed.ncbi.nlm.nih.gov/17591560
https://pubmed.ncbi.nlm.nih.gov/17591560
Publikováno v:
Nuclear Medicine and Biology. 34:593
0969 doi:1 “According to the ex vivo study of Mitterhauser et al. [49] with rats, FETT might have adequate selectivity to visualize DAT and might merit further investigation. Unfortunately, we cannot confirm these findings.” to: “According to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe449b920ac14edc8a4d020b6e5b4c43
https://doi.org/10.1016/j.nucmedbio.2007.04.009
https://doi.org/10.1016/j.nucmedbio.2007.04.009