Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Birsen Can Demirdöğen"'
Autor:
Christina Morgenstern, Isabel Lastres-Becker, Birsen Can Demirdöğen, Vera Marisa Costa, Andreas Daiber, Roberta Foresti, Roberto Motterlini, Sibel Kalyoncu, Burak I. Arioz, Sermin Genc, Monika Jakubowska, Ioannis P. Trougakos, Aleksandra Piechota-Polanczyk, Michel Mickael, Marlene Santos, Thomas W. Kensler, Antonio Cuadrado, Ian M. Copple
Publikováno v:
Redox Biology, Vol 72, Iss , Pp 103134- (2024)
The cytoprotective transcription factor NRF2 regulates the expression of several hundred genes in mammalian cells and is a promising therapeutic target in a number of diseases associated with oxidative stress and inflammation. Hence, an ability to mo
Externí odkaz:
https://doaj.org/article/f50d81e6b4e544bc8942767d3919a61a
Publikováno v:
BMC Ophthalmology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Purpose Pseudoexfoliation syndrome (PEX) is distinguished by the deposition of fibrillary material within the aqueous humor and, in most cases, causes pseudoexfoliative glaucoma (PEG). The pathophysiologies of PEX and PEG are not completely
Externí odkaz:
https://doaj.org/article/94a57d63682a49ba94b8d1b9a2014139
Autor:
Birsen Can Demirdöğen, Osman Oğuzhan Kılıç, Elif Naz Karagülle, Latife Mekselina Kalmaz, Semra Mungan
Publikováno v:
Neurological Sciences. 43:3867-3877
This study aimed to explore the possible association of single nucleotide polymorphisms (SNPs) in the upstream (rs9402373) and downstream regions (rs9399005 and rs12526196) of the gene encoding connective tissue growth factor (CTGF/CCN2) with relapsi
Autor:
null Birsen Can Demirdöğen, null Osman Oğuzhan Kiliç, null Ata Ayhan Yilmaz, null Semra Mungan, null Salim Neşelioğlu, null Özcan Erel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c13d82fa249c280a7430250915a4930
https://doi.org/10.1002/jnr.25163/v3/response1
https://doi.org/10.1002/jnr.25163/v3/response1
Autor:
Birsen Can Demirdöğen, Osman Oğuzhan Kiliç, Ata Ayhan Yilmaz, Semra Mungan, Salim Neşelioğlu, Özcan Erel
Publikováno v:
Journal of neuroscience researchREFERENCES.
This study aimed to assess the possible association between cognitive impairment and two important biochemical biomarkers of oxidative stress, thiol-disulfide homeostasis (TDH), and ischemia-modified albumin (IMA) in patients with multiple sclerosis
Autor:
Özkan İş, Xue Wang, Joseph S. Reddy, Yuhao Min, Elanur Yilmaz, Prabesh Bhattarai, Tulsi Patel, Jeremiah Bergman, Zachary Quicksall, Michael G. Heckman, Frederick Q. Tutor-New, Birsen Can Demirdogen, Launia White, Shunsuke Koga, Vincent Krause, Yasuteru Inoue, Takahisa Kanekiyo, Mehmet Ilyas Cosacak, Nastasia Nelson, Annie J. Lee, Badri Vardarajan, Richard Mayeux, Naomi Kouri, Kaancan Deniz, Troy Carnwath, Stephanie R. Oatman, Laura J. Lewis-Tuffin, Thuy Nguyen, for the Alzheimer’s Disease Neuroimaging Initiative, Minerva M. Carrasquillo, Jonathan Graff-Radford, Ronald C. Petersen, Clifford R. Jr Jack, Kejal Kantarci, Melissa E. Murray, Kwangsik Nho, Andrew J. Saykin, Dennis W. Dickson, Caghan Kizil, Mariet Allen, Nilüfer Ertekin-Taner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract To uncover molecular changes underlying blood-brain-barrier dysfunction in Alzheimer’s disease, we performed single nucleus RNA sequencing in 24 Alzheimer’s disease and control brains and focused on vascular and astrocyte clusters as mai
Externí odkaz:
https://doaj.org/article/0f4d86fabcd9496f8761615d7234bc5b
Autor:
Birsen Can Demirdöğen
Publikováno v:
Multiple Sclerosis and Related Disorders. 68:104232
Nanomedicine offers great promise to solve healthcare problems using nanotechnology. Theranostics provide imaging/diagnosis and therapy simultaneously. Novel agents that target both the neuroinflammation and neurodegeneration component of multiple sc
Autor:
Emre Evin, Birsen Can Demirdöğen, Şeref Demirkaya, Eda Sezer, Merve Akkulak, Giray Bulut, Orhan Adali
Publikováno v:
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 43(4)
Patients with multiple sclerosis (MS) have significantly lower vitamin D levels. Cholesterol is known to be the precursor for vitamin D synthesis, and cholesterol removal is regulated by cholesterol 7α-hydroxylase (CYP7A1) in the liver and cholester
Purpose: Pseudoexfoliation syndrome (PEX) is an age-related disorder of the extracellular matrix characterized by the accumulation of fibrillary deposits in the anterior chamber of the eye, which leads to the development of pseudoexfoliative glaucoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd120ccb60e814a7197d1fe81c6da7c
http://hdl.handle.net/20.500.11851/3679
http://hdl.handle.net/20.500.11851/3679
Publikováno v:
Neurological Research. 41:118-124
Objectives: Oxidative stress is a known risk factor for the pathogenesis of atherosclerosis, the main cause of ischemic stroke. Glutathione S-transferase (GST) omega-1 and omega-2, members of phase II enzymes, play a role in the antioxidant system. T