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Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release.

Autor: Scott JW; Protein Chemistry & Metabolism Unit, St Vincent's Institute of Medical Research and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, VIC 3065, Australia. Electronic address: jscott@svi.edu.au., Galic S; Protein Chemistry & Metabolism Unit, St Vincent's Institute of Medical Research and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, VIC 3065, Australia., Graham KL; Immunology and Diabetes Unit, St Vincent's Institute of Medical Research, 41 Victoria Parade, Fitzroy, VIC 3065, Australia., Foitzik R; Cancer Therapeutics CRC Pty Ltd, Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia., Ling NX; Protein Chemistry & Metabolism Unit, St Vincent's Institute of Medical Research and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, VIC 3065, Australia., Dite TA; Protein Chemistry & Metabolism Unit, St Vincent's Institute of Medical Research and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, VIC 3065, Australia., Issa SM; Protein Chemistry & Metabolism Unit, St Vincent's Institute of Medical Research and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, VIC 3065, Australia., Langendorf CG; Protein Chemistry & Metabolism Unit, St Vincent's Institute of Medical Research and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, VIC 3065, Australia., Weng QP; Mercury Therapeutics Inc., 175 East New Boston Street, Woburn, MA 01801, USA., Thomas HE; Immunology and Diabetes Unit, St Vincent's Institute of Medical Research, 41 Victoria Parade, Fitzroy, VIC 3065, Australia., Kay TW; Immunology and Diabetes Unit, St Vincent's Institute of Medical Research, 41 Victoria Parade, Fitzroy, VIC 3065, Australia., Birnberg NC; Mercury Therapeutics Inc., 175 East New Boston Street, Woburn, MA 01801, USA., Steinberg GR; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada., Kemp BE; Protein Chemistry & Metabolism Unit, St Vincent's Institute of Medical Research and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, VIC 3065, Australia., Oakhill JS; Protein Chemistry & Metabolism Unit, St Vincent's Institute of Medical Research and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, VIC 3065, Australia. Electronic address: joakhill@svi.edu.au.

Publikováno v: Chemistry & biology [Chem Biol] 2015 Jun 18; Vol. 22 (6), pp. 705-11.

Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. 1982.

Autor: Palmiter RD, Brinster RL, Hammer RE, Trumbauer ME, Rosenfeld MG, Birnberg NC, Evans RM

Publikováno v: Biotechnology (Reading, Mass.) [Biotechnology] 1992; Vol. 24, pp. 429-33.

Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes.

Autor: Palmiter RD, Brinster RL, Hammer RE, Trumbauer ME, Rosenfeld MG, Birnberg NC, Evans RM

Publikováno v: Nature [Nature] 1982 Dec 16; Vol. 300 (5893), pp. 611-5.