Zobrazeno 1 - 10
of 1 630
pro vyhledávání: '"Birnbaum Daniel"'
Autor:
Murati Anne, Brecqueville Mandy, Devillier Raynier, Mozziconacci Marie-Joelle, Gelsi-Boyer Véronique, Birnbaum Daniel
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 304 (2012)
Abstract Myeloid malignant diseases comprise chronic (including myelodysplastic syndromes, myeloproliferative neoplasms and chronic myelomonocytic leukemia) and acute (acute myeloid leukemia) stages. They are clonal diseases arising in hematopoietic
Externí odkaz:
https://doaj.org/article/5c3f29012b3c47b38e594bd1381aeac9
Autor:
Gelsi-Boyer Véronique, Brecqueville Mandy, Devillier Raynier, Murati Anne, Mozziconacci Marie-Joelle, Birnbaum Daniel
Publikováno v:
Journal of Hematology & Oncology, Vol 5, Iss 1, p 12 (2012)
Abstract The ASXL1 gene is one of the most frequently mutated genes in malignant myeloid diseases. The ASXL1 protein belongs to protein complexes involved in the epigenetic regulation of gene expression. ASXL1 mutations are found in myeloproliferativ
Externí odkaz:
https://doaj.org/article/e6aa47128bce44b0bf2c7b6c8435c6de
Autor:
Jacquemier Jocelyne, Lambaudie Eric, Cervera Nathalie, Raynaud Stéphane, Mamessier Emilie, Finetti Pascal, Sabatier Renaud, Viens Patrice, Birnbaum Daniel, Bertucci François
Publikováno v:
Molecular Cancer, Vol 10, Iss 1, p 86 (2011)
Abstract Background Basal breast cancers (BCs) represent ~15% of BCs. Although overall poor, prognosis is heterogeneous. Identification of good- versus poor-prognosis patients is difficult or impossible using the standard histoclinical features and t
Externí odkaz:
https://doaj.org/article/af41e3b488394ecea33f3e8ffa750b95
Autor:
Ayed Farhat, Tarpin Carole, Charafe-Jauffret Emmanuelle, Innocenti Charlène, Raynaud Stéphane, Bonansea Julien, Hamida Azza, Adélaïde José, Finetti Pascal, Bekhouche Ismahane, Sircoulomb Fabrice, Viens Patrice, Jacquemier Jocelyne, Bertucci François, Birnbaum Daniel, Chaffanet Max
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 539 (2010)
Abstract Background Around 20% of breast cancers (BC) show ERBB2 gene amplification and overexpression of the ERBB2 tyrosine kinase receptor. They are associated with a poor prognosis but can benefit from targeted therapy. A better knowledge of these
Externí odkaz:
https://doaj.org/article/982e4bb11c4d46a680bd188f03665a20
Autor:
Vey Norbert, Olschwang Sylviane, Tadrist Zoulika, Nezri Meyer, Murati Anne, Raynaud Stéphane, Trouplin Virginie, Carbuccia Nadine, Rocquain Julien, Birnbaum Daniel, Gelsi-Boyer Véronique, Mozziconacci Marie-Joelle
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 401 (2010)
Abstract Background Gene mutation is an important mechanism of myeloid leukemogenesis. However, the number and combination of gene mutated in myeloid malignancies is still a matter of investigation. Methods We searched for mutations in the ASXL1, CBL
Externí odkaz:
https://doaj.org/article/9eb9da75995e44b686561616f8a65f78
Autor:
Addou-Klouche Lynda, Adélaïde José, Finetti Pascal, Cervera Nathalie, Ferrari Anthony, Bekhouche Ismahane, Sircoulomb Fabrice, Sotiriou Christos, Viens Patrice, Moulessehoul Soraya, Bertucci François, Birnbaum Daniel, Chaffanet Max
Publikováno v:
Molecular Cancer, Vol 9, Iss 1, p 213 (2010)
Abstract Background Many alterations are involved in mammary oncogenesis, including amplifications of oncogenes and losses of tumor suppressor genes (TSG). Losses may affect almost all chromosome arms and many TSGs remain to be identified. Results We
Externí odkaz:
https://doaj.org/article/fc19caca2ca14c35a6667e7cac59be8b
Publikováno v:
BMC Cancer, Vol 9, Iss 1, p 202 (2009)
Abstract There is increasing evidence for the "cancer stem cell (CSC) hypothesis", which holds that cancers are driven by a cellular component that has stem cell properties, including self-renewal, tumorigenicity and multi-lineage differentiation cap
Externí odkaz:
https://doaj.org/article/cb05c21d446b4dd8abc1ec9519462416
Publikováno v:
Cancer Cell International, Vol 9, Iss 1, p 5 (2009)
Abstract Alterations of receptor-type tyrosine kinases (RTK) are frequent in human cancers. They can result from translocation, mutation or amplification. The ERBB2 RTK is encoded by a gene that is amplified in about 20% breast cancers. The question
Externí odkaz:
https://doaj.org/article/c48e43084a4c4349b67e1f63826db99c
Autor:
Olschwang Sylviane, Bentires-Alj Mohamed, Sainty Danielle, Arnoulet Christine, Pinson Stephane, Houdayer Claude, Aceto Nicola, Remy Virginie, Adélaïde José, Trouplin Virginie, Gelsi-Boyer Véronique, Vey Norbert, Mozziconacci Marie-Joëlle, Birnbaum Daniel, Chaffanet Max
Publikováno v:
BMC Cancer, Vol 8, Iss 1, p 299 (2008)
Abstract Background Chronic myelomonocytic leukemia (CMML) is a hematological disease close to, but separate from both myeloproliferative disorders (MPD) and myelodysplastic syndromes and may show either myeloproliferative (MP-CMML) or myelodysplasti
Externí odkaz:
https://doaj.org/article/2bce5ff6f46f47a6a8ad4e2cf7676896