Migraine inhibitor olcegepant reduces weight loss and IL-6 release in SARS-CoV-2-infected older mice with neurological signs.

Autor: Rahman SM; Departments of Biomedical Engineering, Neuroscience, Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA., Buchholz DW; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA., Imbiakha B; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA., Jager MC; Department of Population Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA., Leach J; Departments of Biomedical Engineering, Neuroscience, Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA., Osborn RM; Departments of Biomedical Engineering, Neuroscience, Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA., Birmingham AO; Departments of Biomedical Engineering, Neuroscience, Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA., Dewhurst S; Departments of Biomedical Engineering, Neuroscience, Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA., Aguilar HC; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA., Luebke AE; Departments of Biomedical Engineering, Neuroscience, Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA.

Publikováno v: Journal of virology [J Virol] 2024 Jul 23; Vol. 98 (7), pp. e0006624. Date of Electronic Publication: 2024 May 30.