Zeb2 DNA-Binding Sites in Neuroprogenitor Cells Reveal Autoregulation and Affirm Neurodevelopmental Defects, Including in Mowat-Wilson Syndrome.

Autor: Birkhoff JC; Department of Cell Biology, Erasmus University Medical Center, 3015 Rotterdam, The Netherlands., Korporaal AL; Department of Cell Biology, Erasmus University Medical Center, 3015 Rotterdam, The Netherlands., Brouwer RWW; Center for Biomics-Genomics, Erasmus University Medical Center, 3015 Rotterdam, The Netherlands., Nowosad K; Department of Cell Biology, Erasmus University Medical Center, 3015 Rotterdam, The Netherlands.; Department of Biochemistry and Molecular Biology, Medical University of Lublin, 20-093 Lublin, Poland.; The Postgraduate School of Molecular Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland., Milazzo C; Department of Cell Biology, Erasmus University Medical Center, 3015 Rotterdam, The Netherlands., Mouratidou L; Department of Cell Biology, Erasmus University Medical Center, 3015 Rotterdam, The Netherlands., van den Hout MCGN; Center for Biomics-Genomics, Erasmus University Medical Center, 3015 Rotterdam, The Netherlands., van IJcken WFJ; Department of Cell Biology, Erasmus University Medical Center, 3015 Rotterdam, The Netherlands.; Center for Biomics-Genomics, Erasmus University Medical Center, 3015 Rotterdam, The Netherlands., Huylebroeck D; Department of Cell Biology, Erasmus University Medical Center, 3015 Rotterdam, The Netherlands.; Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium., Conidi A; Department of Cell Biology, Erasmus University Medical Center, 3015 Rotterdam, The Netherlands.

Publikováno v: Genes [Genes (Basel)] 2023 Mar 02; Vol. 14 (3). Date of Electronic Publication: 2023 Mar 02.

Targeted chromatin conformation analysis identifies novel distal neural enhancers of ZEB2 in pluripotent stem cell differentiation.

Autor: Birkhoff JC; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands., Brouwer RWW; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands.; Center for Biomics, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands., Kolovos P; Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis 68100, Greece., Korporaal AL; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands., Bermejo-Santos A; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands., Boltsis I; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands., Nowosad K; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands.; Department of Biochemistry and Molecular Biology, Medical University of Lublin, Lublin 20-093, Poland., van den Hout MCGN; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands.; Center for Biomics, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands., Grosveld FG; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands., van IJcken WFJ; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands.; Center for Biomics, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands., Huylebroeck D; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands.; Department of Development and Regeneration, KU Leuven, Leuven B-3000, Belgium., Conidi A; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, CN 3015, The Netherlands.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2020 Aug 29; Vol. 29 (15), pp. 2535-2550.