Zobrazeno 1 - 10
of 237
pro vyhledávání: '"Birke, J."'
Autor:
Wenting You, Kèvin Knoops, Tos T. J. M. Berendschot, Birke J. Benedikter, Carroll A. B. Webers, Chris P. M. Reutelingsperger, Theo G. M. F. Gorgels
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Neurodegenerative disorders are characterized by the progressive loss of structure and function of neurons, often including the death of the neuron. Previously, we reported that, by removing the cell death stimulus, dying/injured neurons cou
Externí odkaz:
https://doaj.org/article/79a3df36649b441587b92cb9388139f3
Autor:
Christy B. M. Tulen, Cheryl van de Wetering, Caspar H. J. Schiffers, Ellen Weltjens, Birke J. Benedikter, Pieter A. Leermakers, Juliana H. Boukhaled, Marie-José Drittij, Bernd T. Schmeck, Niki L. Reynaert, Antoon Opperhuizen, Frederik-Jan van Schooten, Alexander H. V. Remels
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Abnormal mitochondria have been observed in bronchial- and alveolar epithelial cells of patients with chronic obstructive pulmonary disease (COPD). However, it is unknown if alterations in the molecular pathways regulating mitochondrial turn
Externí odkaz:
https://doaj.org/article/0db4c07e4b22467d8642273fe6ed38c9
Autor:
Wenting You, Kèvin Knoops, Iris Boesten, Tos T. J. M. Berendschot, Marc A. M. J. van Zandvoort, Birke J. Benedikter, Carroll A. B. Webers, Chris P. M. Reutelingsperger, Theo G. M. F. Gorgels
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Retinal ganglion cell (RGC) degeneration and death cause vision loss in patients with glaucoma. Regulated cell death, once initiated, is generally considered to be an irreversible process. Recently, we showed that, by timely remov
Externí odkaz:
https://doaj.org/article/56b392ced19f4d30bbfaa74e7ae5117f
Autor:
Björn Klabunde, André Wesener, Wilhelm Bertrams, Isabell Beinborn, Nicole Paczia, Kristin Surmann, Sascha Blankenburg, Jochen Wilhelm, Javier Serrania, Kèvin Knoops, Eslam M. Elsayed, Katrin Laakmann, Anna Lena Jung, Andreas Kirschbaum, Sven Hammerschmidt, Belal Alshaar, Nicolas Gisch, Mobarak Abu Mraheil, Anke Becker, Uwe Völker, Evelyn Vollmeister, Birke J. Benedikter, Bernd Schmeck
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Lower respiratory tract infections caused by Streptococcus pneumoniae (Spn) are a leading cause of death globally. Here we investigate the bronchial epithelial cellular response to Spn infection on a transcriptomic, proteomic and metabolic l
Externí odkaz:
https://doaj.org/article/f53e17d7ffee4a8b866fd16db80c5bb8
Autor:
Björn Klabunde, André Wesener, Wilhelm Bertrams, Stephan Ringshandl, Luke D. Halder, Evelyn Vollmeister, Bernd Schmeck, Birke J. Benedikter
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Lung infections caused by Streptococcus pneumonia are a global leading cause of death. The reactive oxygen species H2O2 is one of the virulence factors of Streptococcus pneumoniae. The Golgi apparatus is essential for the inflamma
Externí odkaz:
https://doaj.org/article/55b9010d63cd4bee8e868367fb2bf524
Autor:
Antoni Vallbona-Garcia, Patrick J. Lindsey, Rick Kamps, Alphons P. M. Stassen, Nhan Nguyen, Florence H. J. van Tienen, Ilse H. J. Hamers, Rianne Hardij, Marike W. van Gisbergen, Birke J. Benedikter, Irenaeus F. M. de Coo, Carroll A. B. Webers, Theo G. M. F. Gorgels, Hubert J. M. Smeets
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2024)
IntroductionPrimary open-angle glaucoma (POAG) is a characteristic optic neuropathy, caused by degeneration of the optic nerve-forming neurons, the retinal ganglion cells (RGCs). High intraocular pressure (IOP) and aging have been identified as major
Externí odkaz:
https://doaj.org/article/6d3868ee3c8f44a88fd87508edffd404
Autor:
Vallbona-Garcia, Antoni, Hamers, Ilse H.J., van Tienen, Florence H.J., Ochoteco-Asensio, Juan, Berendschot, Tos T.J.M., de Coo, Irenaeus F.M., Benedikter, Birke J., Webers, Carroll A.B., Smeets, Hubert J.M., Gorgels, Theo G.M.F.
Publikováno v:
In Experimental Eye Research July 2023 232
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Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Chronic obstructive pulmonary disease (COPD) kills over three million people worldwide every year. Despite its high global impact, the knowledge about the underlying molecular mechanisms is still limited. In this study, we aimed to extend th
Externí odkaz:
https://doaj.org/article/349f22dbbe944fe8b92fb7e7f7a439a9
Akademický článek
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