Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Birgitte R. Kornum"'
Autor:
Hanna M. Ollila, Eilon Sharon, Ling Lin, Nasa Sinnott-Armstrong, Aditya Ambati, Selina M. Yogeshwar, Ryan P. Hillary, Otto Jolanki, Juliette Faraco, Mali Einen, Guo Luo, Jing Zhang, Fang Han, Han Yan, Xiao Song Dong, Jing Li, Jun Zhang, Seung-Chul Hong, Tae Won Kim, Yves Dauvilliers, Lucie Barateau, Gert Jan Lammers, Rolf Fronczek, Geert Mayer, Joan Santamaria, Isabelle Arnulf, Stine Knudsen-Heier, May Kristin Lyamouri Bredahl, Per Medbøe Thorsby, Giuseppe Plazzi, Fabio Pizza, Monica Moresco, Catherine Crowe, Stephen K. Van den Eeden, Michel Lecendreux, Patrice Bourgin, Takashi Kanbayashi, Francisco J. Martínez-Orozco, Rosa Peraita-Adrados, Antonio Benetó, Jacques Montplaisir, Alex Desautels, Yu-Shu Huang, FinnGen, Poul Jennum, Sona Nevsimalova, David Kemlink, Alex Iranzo, Sebastiaan Overeem, Aleksandra Wierzbicka, Peter Geisler, Karel Sonka, Makoto Honda, Birgit Högl, Ambra Stefani, Fernando Morgadinho Coelho, Vilma Mantovani, Eva Feketeova, Mia Wadelius, Niclas Eriksson, Hans Smedje, Pär Hallberg, Per Egil Hesla, David Rye, Zerrin Pelin, Luigi Ferini-Strambi, Claudio L. Bassetti, Johannes Mathis, Ramin Khatami, Adi Aran, Sheela Nampoothiri, Tomas Olsson, Ingrid Kockum, Markku Partinen, Markus Perola, Birgitte R. Kornum, Sina Rueger, Juliane Winkelmann, Taku Miyagawa, Hiromi Toyoda, Seik-Soon Khor, Mihoko Shimada, Katsushi Tokunaga, Manuel Rivas, Jonathan K. Pritchard, Neil Risch, Zoltan Kutalik, Ruth O’Hara, Joachim Hallmayer, Chun Jimmie Ye, Emmanuel J. Mignot
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Narcolepsy type 1 (NT1) is caused by a loss of hypocretin/orexin transmission. Risk factors include pandemic 2009 H1N1 influenza A infection and immunization with Pandemrix®. Here, we dissect disease mechanisms and interactions with environ
Externí odkaz:
https://doaj.org/article/5ce5735744474cff8886bce42fe536b9
Autor:
Marie A. Bentsen, Dylan M. Rausch, Zaman Mirzadeh, Kenjiro Muta, Jarrad M. Scarlett, Jenny M. Brown, Vicente Herranz-Pérez, Arian F. Baquero, Jonatan Thompson, Kimberly M. Alonge, Chelsea L. Faber, Karl J. Kaiyala, Camdin Bennett, Charles Pyke, Cecilia Ratner, Kristoffer L. Egerod, Birgitte Holst, Thomas H. Meek, Burak Kutlu, Yu Zhang, Thomas Sparso, Kevin L. Grove, Gregory J. Morton, Birgitte R. Kornum, José-Manuel García-Verdugo, Anna Secher, Rasmus Jorgensen, Michael W. Schwartz, Tune H. Pers
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
In rodent models of type 2 diabetes, sustained remission of hyperglycemia can be induced by FGF1 action in the mediobasal hypothalamus. Here, the authors show that FGF1-injection is followed by marked changes in glial cell populations and that the su
Externí odkaz:
https://doaj.org/article/3be801c6633040a49c4814f636359746
Autor:
Karin Dreisig, Louise Sund, Maja Wallentin Dommer, Nikolaj Pagh Kristensen, Kim Boddum, Rannveig Viste, Simon Fredholm, Niels Odum, Marja Jäättelä, Søren Skov, Birgitte R. Kornum
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Adenosine triphosphate (ATP) is known to induce cell death in T lymphocytes at high extracellular concentrations. CD4+ and CD8+ T lymphocytes have a differential response to ATP, which in mice is due to differences in the P2X7 receptor expression lev
Externí odkaz:
https://doaj.org/article/11d770213cdf4559ab041b15f59870d7
Publikováno v:
Trends in molecular medicine.
Excessive daytime sleepiness (EDS) is a complex symptom characterized by a strong urge to sleep during daytime accompanied by problems such as attention deficits, anxiety, and lower cognitive performance. The efficacy of treatments for EDS is determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bced32adec24d8ee17b9f1a7d8376d4d
https://pubmed.ncbi.nlm.nih.gov/36400667
https://pubmed.ncbi.nlm.nih.gov/36400667
Autor:
Rannveig Viste, Louise F Follin, Birgitte R Kornum, Benedicte A Lie, Marte K Viken, Per M Thorsby, Terje Rootwelt, Julie A E Christensen, Stine Knudsen-Heier
Publikováno v:
Viste, R, Follin, L F, Kornum, B R, Lie, B A, Viken, M K, Thorsby, P M, Rootwelt, T, Christensen, J A E & Knudsen-Heier, S 2023, ' Increased muscle activity during sleep and more RBD symptoms in H1N1-(Pandemrix)-vaccinated narcolepsy type 1 patients compared with their non-narcoleptic siblings ', Sleep, vol. 46, no. 3 . https://doi.org/10.1093/sleep/zsac316
Study ObjectivesNarcolepsy type 1 (NT1) is characterized by unstable sleep-wake and muscle tonus regulation during sleep. We characterized dream enactment and muscle activity during sleep in a cohort of post-H1N1 NT1 patients and their siblings, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed1673977225da59398aa70e60f60ea
https://pubmed.ncbi.nlm.nih.gov/36562330
https://pubmed.ncbi.nlm.nih.gov/36562330
Autor:
Anja Holm, Marie-Laure Possovre, Mojtaba Bandarabadi, Kristine F. Moseholm, Jessica L. Justinussen, Ivan Bozic, René Lemcke, Yoan Arribat, Francesca Amati, Asli Silahtaroglu, Maxime Juventin, Antoine Adamantidis, Mehdi Tafti, Birgitte R. Kornum
Publikováno v:
Holm, Anja; Possovre, Marie-Laure; Bandarabadi, Mojtaba; Moseholm, Kristine F; Justinussen, Jessica L; Bozic, Ivan; Lemcke, René; Arribat, Yoan; Amati, Francesca; Silahtaroglu, Asli; Juventin, Maxime; Adamantidis, Antoine; Tafti, Mehdi; Kornum, Birgitte R (2022). The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio. Proceedings of the National Academy of Sciences of the United States of America-PNAS, 119(17), e2112225119. National Academy of Sciences NAS 10.1073/pnas.2112225119
Holm, A, Possovre, M-L, Bandarabadi, M, Moseholm, K F, Justinussen, J L, Bozic, I, Lemcke, R, Arribat, Y, Amati, F, Silahtaroglu, A, Juventin, M, Adamantidis, A, Tafti, M & Kornum, B R 2022, ' The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17, e2112225119, pp. e2112225119 . https://doi.org/10.1073/pnas.2112225119
Holm, A, Possovre, M L, Bandarabadi, M, Moseholm, K F, Justinussen, J L, Bozic, I, Lemcke, R, Arribat, Y, Amati, F, Silahtaroglu, A, Juventin, M, Adamantidis, A, Tafti, M & Kornum, B R 2022, ' The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17 . https://doi.org/10.1073/pnas.2112225119
Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17, pp. e2112225119
Holm, A, Possovre, M-L, Bandarabadi, M, Moseholm, K F, Justinussen, J L, Bozic, I, Lemcke, R, Arribat, Y, Amati, F, Silahtaroglu, A, Juventin, M, Adamantidis, A, Tafti, M & Kornum, B R 2022, ' The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17, e2112225119, pp. e2112225119 . https://doi.org/10.1073/pnas.2112225119
Holm, A, Possovre, M L, Bandarabadi, M, Moseholm, K F, Justinussen, J L, Bozic, I, Lemcke, R, Arribat, Y, Amati, F, Silahtaroglu, A, Juventin, M, Adamantidis, A, Tafti, M & Kornum, B R 2022, ' The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17 . https://doi.org/10.1073/pnas.2112225119
Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17, pp. e2112225119
Hypocretin (Hcrt), also known as orexin, neuropeptide signaling stabilizes sleep and wakefulness in all vertebrates. A lack of Hcrt causes the sleep disorder narcolepsy, and increased Hcrt signaling has been speculated to cause insomnia, but while th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5daa4e77ffd8aa8cbc665cd9fc957acc
https://boris.unibe.ch/169463/1/pnas.2112225119.pdf
https://boris.unibe.ch/169463/1/pnas.2112225119.pdf
Autor:
Rannveig, Viste, Benedicte A, Lie, Marte K, Viken, Terje, Rootwelt, Stine, Knudsen-Heier, Birgitte R, Kornum
Publikováno v:
Sleep medicine. 85
Evidence suggests a cell-mediated autoimmune pathogenesis for narcolepsy type 1 (NT1), but it is not clear whether the disease is associated with overall changes in T cell subsets. The increase in NT1 incidence after H1N1 vaccination campaign with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f6fac04cefcaa51ecc84a246ee4e296
https://pubmed.ncbi.nlm.nih.gov/34388506
https://pubmed.ncbi.nlm.nih.gov/34388506
Publikováno v:
J Neurosci
Hauglund, N L, Kusk, P, Kornum, B R & Nedergaard, M 2020, ' Meningeal Lymphangiogenesis and Enhanced Glymphatic Activity in Mice with Chronically Implanted EEG Electrodes ', Journal of Neuroscience, vol. 40, no. 11, pp. 2371-2380 . https://doi.org/10.1523/JNEUROSCI.2223-19.2020
Hauglund, N L, Kusk, P, Kornum, B R & Nedergaard, M 2020, ' Meningeal Lymphangiogenesis and Enhanced Glymphatic Activity in Mice with Chronically Implanted EEG Electrodes ', Journal of Neuroscience, vol. 40, no. 11, pp. 2371-2380 . https://doi.org/10.1523/JNEUROSCI.2223-19.2020
Chronic electroencephalography (EEG) is a widely used tool for monitoring cortical electrical activity in experimental animals. Although chronic implants allow for high-quality, long-term recordings in preclinical studies, the electrodes are foreign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981db56b604aabcdec01c2ee0277f67b
https://europepmc.org/articles/PMC7083292/
https://europepmc.org/articles/PMC7083292/
Autor:
Hanna M Ollila, Eilon Sharon, Ling Lin, Nasa Sinnott-Armstrong, Aditya Ambati, Ryan P Hillary, Otto Jolanki, Juliette Faraco, Mali Einen, Guo Luo, Jing Zhang, Fang Han, Han Yan, Xiao Song Dong, Jing Li, Jun Zhang, Seung-Chul Hong, Tae Won Kim, Yves Dauvilliers, Lucie Barateau, Gert Jan Lammers, Rolf Fronczek, Geert Mayer, Joan Santamaria, Isabelle Arnulf, Stine Knudsen, May Kristin Lyamouri Bredahl, Per Medbøe Thorsby, Giuseppe Plazzi, Fabio Pizza, Monica Moresco, Catherine Crowe, Stephen K Van den Eeden, Michel Lecendreux, Patrice Bourgin, Takashi Kanbayashi, Rosa Peraita-Adrados, Francisco J Martínez-Orozco, Antonio Benetó, Jacques Montplaisir, Alex Desautels, Yu-Shu Huang, Poul Jennum, Sona Nevsimalova, David Kemlink, Alex Iranzo, Sebastian Overeem, Aleksandra Wierzbicka, Peter Geisler, Karel Sonka, Makoto Honda, Birgit Högl, Ambra Stefani, Fernando Morgadinho Coelho, Vilma Mantovani, Eva Feketeova, Mia Wadelius, Niclas Eriksson, Hans Smedje, Pär Hallberg, Per Egil Hesla, David Rye, Zerrin Pelin, Luigi Ferini-Strambi, Claudio L Bassetti, Johannes Mathis, Ramin Khatami, Adi Aran, Sheela Nampoothiri, Tomas Olsson, Ingrid Kockum, Markku Partinen, Markus Perola, Birgitte R Kornum, Sina Rueger, Juliane Winkelmann, Taku Miyagawa, Hiromi Toyoda, Seik Soon Khor, Mihoko Shimada, Katsushi Tokunaga, Manuel Rivas, Jonathan K Pritchard, Neil Risch, Zoltan Kutalik, Ruth O’Hara, Joachim Hallmayer, Chun Jimmie Ye, Emmanuel Mignot
Type 1 narcolepsy (T1N) is a neurological condition, in which the death of hypocretin-producing neurons in the lateral hypothalamus leads to excessive daytime sleepiness and symptoms of abnormal Rapid Eye Movement (REM) sleep. Known triggers for narc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e414fdccc04239b4bae26aad2deecce8
Autor:
Karin, Dreisig, Louise, Sund, Maja Wallentin, Dommer, Nikolaj Pagh, Kristensen, Kim, Boddum, Rannveig, Viste, Simon, Fredholm, Niels, Odum, Marja, Jäättelä, Søren, Skov, Birgitte R, Kornum
Publikováno v:
Frontiers in immunology. 9
Adenosine triphosphate (ATP) is known to induce cell death in T lymphocytes at high extracellular concentrations. CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f8f5f8827076dd6e626baac85b664ec
https://pubmed.ncbi.nlm.nih.gov/29937766
https://pubmed.ncbi.nlm.nih.gov/29937766