Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Birgitte Munch-Petersen"'
Autor:
Mahak Fatima, Muhammad Mubashar Iqbal Ahmed, Faiza Batool, Anjum Riaz, Moazzam Ali, Birgitte Munch-Petersen, Zeeshan Mutahir
Publikováno v:
Biomolecules & Biomedicine, Vol 19, Iss 4 (2019)
A recombinant deoxyribonucleoside kinase from Drosophila melanogaster with a deletion of the last 20 amino acid residues (named DmdNKΔC20) was hypothesized as a potential therapeutic tool for gene therapy due to its broad substrate specificity and b
Externí odkaz:
https://doaj.org/article/09082df056ca48088f55a8618e19c124
Autor:
Louise Slot Christiansen, Dvora Berenstein, Gabriella Christina van Zanten, Søren Kjærulff, Marianne Lauridsen, Birgitte Munch-Petersen, Leif Søndergaard
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 35:699-706
We have previously found that Drosophila melanogaster only has one deoxyribonucleoside kinase, Dm-dNK, however, capable to phosphorylate all four natural deoxyribonucleosides. Dm-dNK was originally isolated from an embryonic cell line. We wanted to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804eff73d37760a7deba347209dc40f8
https://doi.org/10.1080/15257770.2015.1131295
https://doi.org/10.1080/15257770.2015.1131295
Autor:
Louise Slot Christiansen, Anders R. Clausen, Zeeshan Mutahir, Jure Piškur, Zoran Gojkovic, Martin W. Berchtold, Birgitte Munch-Petersen, Wolfgang Knecht
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 35:677-690
Deoxyribonucleoside kinases (dNKs) salvage deoxyribonucleosides (dNs) and catalyze the rate limiting step of this salvage pathway by converting dNs into corresponding monophosphate forms. These enzymes serve as an excellent model to study duplicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c09b6c8e9ad928622a8f5a431f90fa
https://doi.org/10.1080/15257770.2016.1143557
https://doi.org/10.1080/15257770.2016.1143557
Autor:
Muhammad Mubashar Iqbal Ahmed, Moazzam Ali, Birgitte Munch-Petersen, Zeeshan Mutahir, Mahak Fatima, Faiza Batool, Anjum Riaz
Publikováno v:
Bosnian Journal of Basic Medical Sciences (2019)
A recombinant deoxyribonucleoside kinase from Drosophila melanogaster with a deletion of the last 20 amino acid residues (named DmdNKΔC20) was hypothesized as a potential therapeutic tool for gene therapy due to its broad substrate specificity and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e160dca7c7c3836915ca77ee1f907ec
https://www.bjbms.org/ojs/index.php/bjbms/article/view/4136
https://www.bjbms.org/ojs/index.php/bjbms/article/view/4136
Autor:
Immacolata Serra, Birgitte Munch-Petersen, Teodora Bavaro, Marco Terreni, Daniela Ubiali, Jure Piškur
Deoxyadenosine kinase from Dictyostelium discoideum (DddAK) phosphorylates its natural substrate (2’-deoxyadenosine, dAdo) as well as the arabinosyladenine analogues vidarabine (araA) and fludarabine (F-araA) to their corresponding 5’-monophospha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e124b9c29178ccbd8f41f2d080a0f7e
http://hdl.handle.net/10281/316396
http://hdl.handle.net/10281/316396
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 33:287-290
A promising suicide gene therapy system to treat gliomas has been reported: the thymidine kinase 1 from tomato (toTK1) combined with the nucleoside analog pro-drug zidovudine (azidothymidine, AZT), which is known to penetrate the blood-brain barrier.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f155531f0aca9af48e6c0c3a618456d3
https://doi.org/10.1080/15257770.2013.853781
https://doi.org/10.1080/15257770.2013.853781
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 33:291-295
Deoxyribonucleoside kinases phosphorylate deoxyribonucleosides into the corresponding 5'-monophosphate deoxyribonucleosides to supply the cell with nucleic acid precursors. In mitochondrial fractions of the model plant Arabidopsis thaliana, we detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89716f8d1df82d1f6650a93a79b647b
https://doi.org/10.1080/15257770.2013.853782
https://doi.org/10.1080/15257770.2013.853782
Autor:
Birgitte Munch-Petersen, Silvia Conti, Daniela Ubiali, Anders R. Clausen, Marco Terreni, Immacolata Serra, Jure Piškur
Publikováno v:
Advanced Synthesis & Catalysis. 356:563-570
Fruit fly (Drosophila melanogaster) deoxyribonucleoside kinase (DmdNK; EC: 2.7.1.145) was characterized for its substrate specificity towards natural and non-natural nucleosides, confirming its potential in the enzymatic synthesis of modified nucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce5d1c68bae711b9b8c1b38ab2413c1
https://doi.org/10.1002/adsc.201300649
https://doi.org/10.1002/adsc.201300649
Autor:
Zeeshan Mutahir, Jure Piškur, Sofia Mebrahtu Wisén, Birgitte Munch-Petersen, Karl-Magnus Andersson, Anders R. Clausen
Publikováno v:
FEBS Journal. 280:1531-1541
Thymidine kinase 1 (TK1) provides a crucial precursor, deoxythymidine monophosphate, for nucleic acid synthesis, and the activity of TK1 increases by up to 200-fold during the S-phase of cell division in humans. An important part of the regulatory ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908341c4345581bc33e9b9ed21a1e2d6
https://doi.org/10.1111/febs.12154
https://doi.org/10.1111/febs.12154
Autor:
Adnan Ali, Elżbieta Rozpędowska, Erik Andreasson, Jure Piškur, Wolfgang Knecht, Anders R. Clausen, Lenart Girandon, Birgitte Munch-Petersen, Michael P. B. Sandrini
Publikováno v:
FEBS Journal. 279:3889-3897
Deoxyribonucleotides are the building blocks of DNA and can be synthesized via de novo and salvage pathways. Deoxyribonucleoside kinases (EC 2.7.1.145) salvage deoxyribonucleosides by transfer of a phosphate group to the 5' of a deoxyribonucleoside.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5df218fa3f02ba4d70f183af4d3b4c
https://doi.org/10.1111/j.1742-4658.2012.08747.x
https://doi.org/10.1111/j.1742-4658.2012.08747.x