Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Birgitte M. Viuff"'
Autor:
Lykke Boysen, Birgitte M. Viuff, Lone H. Landsy, Shari A. Price, James T. Raymond, Jens Lykkesfeldt, Brian Lauritzen
Publikováno v:
Journal of Immunotoxicology, Vol 16, Iss 1, Pp 191-200 (2019)
In preclinical toxicity studies, species-foreign proteins administered to animals frequently leads to formation of anti-drug antibodies (ADA). Such antibodies may form circulating immune complexes (CIC) with the administered protein. These CIC can ac
Externí odkaz:
https://doaj.org/article/d855541f680949a3afa8da9a8a87a009
Autor:
Charlotte Petersen, Mette D. Nielsen, Elise S. Andersen, Astrid L. Basse, Marie S. Isidor, Lasse K. Markussen, Birgitte M. Viuff, Ian H. Lambert, Jacob B. Hansen, Stine F. Pedersen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Adipose tissue takes up glucose and releases lactate, thereby contributing significantly to systemic glucose and lactate homeostasis. This implies the necessity of upregulation of net acid and lactate flux capacity during adipocyte different
Externí odkaz:
https://doaj.org/article/8bf3e0267a624fd6a5bb3adcd9b1f5ba
Autor:
Brian Lauritzen, Birgitte M. Viuff, Shari A. Price, Lone H. Landsy, Jens Lykkesfeldt, Hermann Pelzer, Lykke Boysen, James T. Raymond
Publikováno v:
Toxicologic Pathology. 48:570-585
Administration of human protein–based drugs to animals often leads to formation of antidrug antibodies (ADAs) that may form circulating immune complexes (CICs) with the dosed protein. Circulating immune complexes can activate and bind complement (c
Autor:
Birgitte M. Viuff, Anne Ejrnaes Sprinkel, Lykke Boysen, Brian Lauritzen, Lone H. Landsy, Jens Breinholt, Jens Lykkesfeldt
Publikováno v:
Biologicals. 60:42-48
Rapid and versatile methods are needed for evaluation of immunogenicity in early safety studies. The present work presents a generic, simple and easy to use sandwich enzyme-linked immunosorbent assay for quasi-quantitative measurement of circulating
Autor:
Brian Lauritzen, Lykke Boysen, Lone H. Landsy, Jens Lykkesfeldt, Birgitte M. Viuff, James T. Raymond, Shari A. Price
Publikováno v:
Journal of Immunotoxicology, Vol 16, Iss 1, Pp 191-200 (2019)
Boysen, L, Viuff, B M, Landsy, L H, Price, S A, Raymond, J T, Lykkesfeldt, J & Lauritzen, B 2019, ' Formation and glomerular deposition of immune complexes in mice administered bovine serum albumin : Evaluation of dose, frequency, and biomarkers ', Journal of Immunotoxicology, vol. 16, no. 1, pp. 191-200 . https://doi.org/10.1080/1547691X.2019.1680776
Boysen, L, Viuff, B M, Landsy, L H, Price, S A, Raymond, J T, Lykkesfeldt, J & Lauritzen, B 2019, ' Formation and glomerular deposition of immune complexes in mice administered bovine serum albumin : Evaluation of dose, frequency, and biomarkers ', Journal of Immunotoxicology, vol. 16, no. 1, pp. 191-200 . https://doi.org/10.1080/1547691X.2019.1680776
In preclinical toxicity studies, species-foreign proteins administered to animals frequently leads to formation of anti-drug antibodies (ADA). Such antibodies may form circulating immune complexes (CIC) with the administered protein. These CIC can ac
Autor:
Jesper Damgaard, Christina Zachodnik, Victoria Svop Jensen, Jens Lykkesfeldt, Rikke Kaae Kirk, Christian Fledelius, Henning Hvid, Birgitte M. Viuff, Erik M. Wulff, Kristina Steinicke Tornqvist, Helle Nygaard
Publikováno v:
Jensen, V S, Fledelius, C, Zachodnik, C, Damgaard, J, Nygaard, H, Tornqvist, K S, Kirk, R K, Viuff, B M, Wulff, E M, Lykkesfeldt, J & Hvid, H 2021, ' Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD ', Journal of Translational Medicine, vol. 19, no. 1, 80 . https://doi.org/10.1186/s12967-021-02729-1
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-21 (2021)
Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-21 (2021)
Journal of Translational Medicine
Background Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are highly prevalent comorbidities in patients with Type 2 diabetes. While many of these patients eventually will need treatment with insulin, little is kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a917bac017a3ff33da1306a6ece26c
https://curis.ku.dk/portal/da/publications/insulin-treatment-improves-liver-histopathology-and-decreases-expression-of-inflammatory-and-fibrogenic-genes-in-a-hyperglycemic-dyslipidemic-hamster-model-of-nafld(ee826b1f-e0b4-46c5-a822-8e8256d2f656).html
https://curis.ku.dk/portal/da/publications/insulin-treatment-improves-liver-histopathology-and-decreases-expression-of-inflammatory-and-fibrogenic-genes-in-a-hyperglycemic-dyslipidemic-hamster-model-of-nafld(ee826b1f-e0b4-46c5-a822-8e8256d2f656).html
Autor:
Birgitte M. Viuff, Peter Helding Kvist, Nikolai K. Jensen, Henning Hvid, Martin B. Oleksiewicz, Mikala Skydsgaard, Henrik Jeldtoft Jensen
Publikováno v:
Toxicologic pathology. 49(4)
Quantitative assessment of proliferation can be an important endpoint in toxicologic pathology. Traditionally, cell proliferation is quantified by labor-intensive manual counting of positive and negative cells after immunohistochemical staining for p
Autor:
Louise Pedersen, Jette Nowak, Pernille Tveden-Nyborg, Anne Marie Mølck, Birgitte M. Viuff, Jens Lykkesfeldt, Vivi F. H. Jensen, Suzi H. Madsen, Kristina Åkesson, Johannes Josef Fels, Ingrid Brück Bøgh, Fiona E. McGuigan, Charlotte Lund Rasmussen
Publikováno v:
Scientific Reports
Jensen, V F H, Mølck, A-M, Bøgh, I B, Nowak, J, Viuff, B M, Rasmussen, C L M, Pedersen, L, Fels, J J, Madsen, S H, McGuigan, F E, Tveden-Nyborg, P, Lykkesfeldt, J & Akesson, K E 2020, ' Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats ', Scientific Reports, vol. 10, no. 1, 5609 . https://doi.org/10.1038/s41598-020-62554-2
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Jensen, V F H, Mølck, A-M, Bøgh, I B, Nowak, J, Viuff, B M, Rasmussen, C L M, Pedersen, L, Fels, J J, Madsen, S H, McGuigan, F E, Tveden-Nyborg, P, Lykkesfeldt, J & Akesson, K E 2020, ' Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats ', Scientific Reports, vol. 10, no. 1, 5609 . https://doi.org/10.1038/s41598-020-62554-2
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Maternal hypoglycaemia throughout gestation until gestation day (GD)20 delays foetal growth and skeletal development. While partially prevented by return to normoglycaemia after completed organogenesis (GD17), underlying mechanisms are not fully unde
Publikováno v:
Journal of Immunotoxicology, Vol 16, Iss 1, Pp 82-86 (2019)
Boysen, L, Lauritzen, B, Viuff, B M, Lykkesfeldt, J & Landsy, L H 2019, ' An ELISA for detection of complement-bound circulating immune complexes in mice ', Journal of Immunotoxicology, vol. 16, no. 1, pp. 82-86 . https://doi.org/10.1080/1547691X.2019.1599471
Boysen, L, Lauritzen, B, Viuff, B M, Lykkesfeldt, J & Landsy, L H 2019, ' An ELISA for detection of complement-bound circulating immune complexes in mice ', Journal of Immunotoxicology, vol. 16, no. 1, pp. 82-86 . https://doi.org/10.1080/1547691X.2019.1599471
Measurements of complement-bound circulating immune complexes (cCICs) in pre-clinical studies may provide important information about the etiology of certain pathology findings suggestive of being immune complex mediated. This article describes the d
Autor:
Sophia G, Moesgaard, Lisbeth H, Olsen, Birgitte M, Viuff, Ulrik, Baandrup, Lotte G, Pedersen, Preben D, Thomsen, Henrik D, Pedersen, Adrian P, Harrison
Publikováno v:
The Journal of heart valve disease. 16(1)
Little is known of the local role of nitric oxide (NO) in heart valves in relation to heart valve diseases. The study aim was to examine NO release and the expression of both endothelial nitric oxide synthase (eNOS) and inducible nitric oxide synthas