Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Birgitte, Federspiel"'
Autor:
Kirstine Nielsen, Tina Binderup, Seppo W. Langer, Andreas Kjaer, Pauline Knigge, Veronica Grøndahl, Linea Melchior, Birgitte Federspiel, Ulrich Knigge
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background High grade gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) with a Ki67 proliferation index > 20%, include well-differentiated tumours grade 3 (NET G3) and poorly differentiated (PD) neuroendocrine carcinomas (NEC). Abn
Externí odkaz:
https://doaj.org/article/c384757899ea4148bfbfb4d4284db073
Autor:
Abir Salwa Ali, Seppo W Langer, Birgitte Federspiel, Geir Olav Hjortland, Henning Grønbæk, Morten Ladekarl, Staffan Welin, Lene Weber Vestermark, Johanna Arola, Pia Osterlund, Ulrich Knigge, Halfdan Sørbye, Patrick Micke, Lars Grimelius, Malin Grönberg, Eva Tiensuu Janson
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243900 (2020)
Gastroenteropancreatic neuroendocrine neoplasms grade 3 (GEP-NENs G3) are rare tumors. These highly aggressive neoplasms are traditionally treated with platinum-based chemotherapy in combination with etoposide. Immune checkpoint proteins such as prog
Externí odkaz:
https://doaj.org/article/ac74ae6268f3457983859932874fe2cc
Autor:
Anna Bryan Stensbøl, Jesper Krogh, Pernille Holmager, Marianne Klose, Peter Oturai, Andreas Kjaer, Carsten Palnæs Hansen, Birgitte Federspiel, Seppo W. Langer, Ulrich Knigge, Mikkel Andreassen
Publikováno v:
Diagnostics, Vol 11, Iss 11, p 2030 (2021)
Background: The incidence of small intestinal (SI) and pancreatic neuroendocrine tumors (siNETs and pNETs) seems to have increased. The increased frequency of incidental findings might be a possible explanation. The study aimed to examine (1) changes
Externí odkaz:
https://doaj.org/article/7d8e6c2923734c5088515b0cfd7b050e
Publikováno v:
Case Reports in Gastroenterology, Vol 10, Iss 2, Pp 466-471 (2016)
Verrucous carcinoma is a rare, slow-growing type of squamous cell cancer. Fewer than 50 patients with verrucous carcinoma in the esophagus have been described worldwide. In 2014, two male patients were diagnosed with verrucous carcinoma in the distal
Externí odkaz:
https://doaj.org/article/8d379d9b55fe4a17b5691a4adaa3f437
Autor:
Jonas Baekdal, Jesper Krogh, Marianne Klose, Pernille Holmager, Seppo W. Langer, Peter Oturai, Andreas Kjaer, Birgitte Federspiel, Linda Hilsted, Jens F. Rehfeld, Ulrich Knigge, Mikkel Andreassen
Publikováno v:
Diagnostics, Vol 10, Iss 11, p 881 (2020)
Background: Plasma chromogranin A (CgA) is related to tumor burden and recommended in the follow-up of patients diagnosed with neuroendocrine tumors (NETs). The use of CgA in the workup of a suspected NET is more questionable. Objective: To assess th
Externí odkaz:
https://doaj.org/article/b8237235186e45d18eaf4b16324b2f83
Autor:
Emma Elizabeth Ilett, Seppo W. Langer, Ingrid Holst Olsen, Birgitte Federspiel, Andreas Kjær, Ulrich Knigge
Publikováno v:
Diagnostics, Vol 5, Iss 2, Pp 119-176 (2015)
To date, empirical literature has generally been considered lacking in relation to neuroendocrine carcinomas (NECs), the highly malignant subgroup of neuroendocrine neoplasms. NECs are often found in the lungs or the gastroenteropancreatic (GEP) syst
Externí odkaz:
https://doaj.org/article/8dc7191b17e84e93bd220485dc6e7769
Autor:
Kristina B. V. Døssing, Tina Binderup, Bogumil Kaczkowski, Anders Jacobsen, Maria Rossing, Ole Winther, Birgitte Federspiel, Ulrich Knigge, Andreas Kjær, Lennart Friis-Hansen
Publikováno v:
Genes, Vol 6, Iss 1, Pp 1-21 (2014)
Expression of miRNAs in Neuroendocrine Neoplasms (NEN) is poorly characterized. We therefore wanted to examine the miRNA expression in Neuroendocrine Tumors (NETs), and identify their targets and importance in NET carcinogenesis. miRNA expression in
Externí odkaz:
https://doaj.org/article/31c7a4977c5947fc806dd491abff0e98
Autor:
Abir Salwa Ali, Malin Grönberg, Birgitte Federspiel, Jean-Yves Scoazec, Geir Olav Hjortland, Henning Grønbæk, Morten Ladekarl, Seppo W Langer, Staffan Welin, Lene Weber Vestermark, Johanna Arola, Pia Österlund, Ulrich Knigge, Halfdan Sorbye, Lars Grimelius, Eva Tiensuu Janson
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187667 (2017)
Gastroenteropancreatic neuroendocrine carcinomas (GEP-NECs) are aggressive, rapidly proliferating tumors. Therapeutic response to current chemotherapy regimens is usually short lasting. The aim of this study was to examine the expression and potentia
Externí odkaz:
https://doaj.org/article/5285c1eba0e445af90c623f9710a9b5f
Autor:
Birgitte Federspiel, Dea Natalie Munch Jepsen, Jakob Holm, Rajendra Singh Garbyal, Anne-Marie Kanstrup Fiehn, Ulla Engel
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 29:454-461
Neuroendocrine neoplasms (NENs) of the esophagogastric junction (EGJ) are uncommon and the classification of these tumors has been revised several times. Since 2016, at the Department of Pathology, Rigshospitalet, Denmark, all adenocarcinomas and poo
Autor:
Pernille Holmager, Seppo W. Langer, Andreas Kjaer, Lene Ringholm, Rajendra Singh Garbyal, Hans-Christian Pommergaard, Carsten Palnæs Hansen, Birgitte Federspiel, Mikkel Andreassen, Ulrich Knigge
Publikováno v:
Current treatment options in oncologyReferences and Recommended ReadingPapers of particular interest, published recently, have been highlighted as: •• Of major importance. 23(6)
In the 2019 WHO guidelines, the classification of gastro-entero-pancreatic neuroendocrine neoplasms (GEP NEN) has changed from one being based on Ki-67 proliferation index alone to one that also includes tumor differentiation. Consequently, GEP NENs