Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Birgitta Slawik"'
Autor:
Christian Riebeling, Andrea Seiler, Matthias Steinfath, Ralph Pirow, Katrin Hayess, Dana Sittner, Andreas Luch, Birgitta Slawik
Publikováno v:
Toxicology. 314:135-147
As the developing brain is exquisitely vulnerable to chemical disturbances, testing for developmental neurotoxicity of a substance is an important aspect of characterizing its tissue specific toxicity. Mouse embryonic stem cells (mESCs) can be differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0bfe7786154ce5f2c46c6fcebd1fe81
https://doi.org/10.1016/j.tox.2013.09.012
https://doi.org/10.1016/j.tox.2013.09.012
Autor:
Christian Riebeling, Birgitta Slawik, Elena E. Pohl, Andrea Seiler, Konrad Gulich, Michael Oelgeschläger, Katrin Hayess, Anke Visan, Dana Sittner, Andreas Luch
Publikováno v:
NeuroToxicology. 33:1135-1146
Mouse embryonic stem cells (mESCs) represent an attractive cellular system for in vitro studies in developmental biology as well as toxicology because of their potential to differentiate into all fetal cell lineages. The present study aims to establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3756a3e9f0d81e9532f094755fc8b33
https://doi.org/10.1016/j.neuro.2012.06.006
https://doi.org/10.1016/j.neuro.2012.06.006
Autor:
Johanna Kaltenhäuser, Daniel Eikel, Heinz Nau, Frauke Meyer, Anke Visan, Andrea Seiler, Ralph Pirow, Christian Riebeling, Andreas Luch, Klaus Becker, Birgitta Slawik, Roland Buesen, Horst Spielmann, Jutta Volland
Publikováno v:
Toxicological Sciences
Teratogenicity can be predicted in vitro using the embryonic stem cell test (EST). The EST, which is based on the morphometric measurement of cardiomyocyte differentiation and cytotoxicity parameters, represents a scientifically validated method for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a59e2c4f9a950aed8ff7766cc96c62
https://pubmed.ncbi.nlm.nih.gov/21227905
https://pubmed.ncbi.nlm.nih.gov/21227905
Autor:
Andreas Luch, Anke Visan, Elke Genschow, Roland Buesen, Horst Spielmann, Birgitta Slawik, Andrea Seiler
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 108(2)
The embryonic stem cell test (EST) represents a reliable, scientifically validated in vitro system for the detection and classification of compounds according to their teratogenic potency. However, some serious issues were frequently raised against t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76146b34240ec2dbf6965e00133474a4
https://pubmed.ncbi.nlm.nih.gov/19168572
https://pubmed.ncbi.nlm.nih.gov/19168572
Autor:
Helena, Kandárová, Manfred, Liebsch, Elke, Genschow, Ingrid, Gerner, Dieter, Traue, Birgitta, Slawik, Horst, Spielmann
Publikováno v:
ALTEX. 21(3)
An ECVAM-funded prevalidation study (PV) was conducted during 1999 and 2000 to identify in vitro tests capable of reliably distinguishing between skin irritants (I) and non-irritants (NI) according to European Union risk phrases ("R38" or no classifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37978103613287d1782d0844be7f0ffb
https://pubmed.ncbi.nlm.nih.gov/15329774
https://pubmed.ncbi.nlm.nih.gov/15329774
Autor:
Roland, Buesen, Anke, Visan, Elke, Genschow, Birgitta, Slawik, Horst, Spielmann, Andrea, Seiler
Publikováno v:
ALTEX. 21(1)
The embryonic stem cell test (EST) is an in vitro assay that has been developed to assess the teratogenic and embryotoxic potential of drugs and chemicals. It is based on the capacity of murine ES cells (cell line D3) to differentiate into contractin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc02d811d90189f9abc0ec297299831d
https://pubmed.ncbi.nlm.nih.gov/14976585
https://pubmed.ncbi.nlm.nih.gov/14976585
Autor:
Roland Buesen, Elke Genschow, Birgitta Slawik, Anke Visan, Horst Spielmann, Andreas Luch, Andrea Seiler
Publikováno v:
Toxicological Sciences; Apr2009, Vol. 108 Issue 2, p389-400, 12p