The pharmacokinetics, safety, and tolerability of mirabegron in children and adolescents with neurogenic detrusor overactivity or idiopathic overactive bladder and development of a population pharmacokinetic model-based pediatric dose estimation

Autor: Camilla Tøndel, Paul Passier, Otto Stroosma, Malgorzata Baka-Ostrowska, Søren Rittig, Brigitte Bosman, Birgitta Kjaeer, Stacey Tannenbaum, Johan Vande Walle

Publikováno v: Rittig, S, Baka-Ostrowska, M, Tøndel, C, Walle, J V, Kjaeer, B, Passier, P, Bosman, B, Stroosma, O & Tannenbaum, S 2020, ' The pharmacokinetics, safety, and tolerability of mirabegron in children and adolescents with neurogenic detrusor overactivity or idiopathic overactive bladder and development of a population pharmacokinetic model-based pediatric dose estimation ', Journal of Pediatric Urology, vol. 16, no. 1, pp. 31.e1-31.e10 . https://doi.org/10.1016/j.jpurol.2019.10.009
Journal of Pediatric Urology

Introduction: Mirabegron, a selective β3-adrenoreceptor agonist, is a well-established alternative to antimuscarinics in adults with overactive bladder (OAB) symptoms and is under development for use in pediatric patients. Understanding drug pharmac

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https://pure.au.dk/portal/da/publications/the-pharmacokinetics-safety-and-tolerability-of-mirabegron-in-children-and-adolescents-with-neurogenic-detrusor-overactivity-or-idiopathic-overactive-bladder-and-development-of-a-population-pharmacokinetic-modelbased-pediatric-dose-estimation(ef3ee9a0-9ef8-4f65-bbad-09ad22a6d4bc).html

Enlightened Monks : The German Benedictines 1740-1803

Autor: Ulrich L. Lehner

Enlightened Monks investigates the social, cultural, philosophical, and theological challenges the German Benedictines had to face between 1740 and 1803, and how the Enlightenment process influenced the self-understanding and lifestyle of these relig