Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Birgitta Gelius"'
Autor:
Lena Gustavsson, Evelyn Hollnack, Adam Jeston Dudley, Birgitta Gelius, Janet Hoogstraate, Ulrica Skoging-Nyberg, Johanna Wahlberg, Jeanette Danielsson, Christina Lohmann
Publikováno v:
Analytical Biochemistry. 366:117-125
Increasing evidence suggests a key role of transport proteins in the pharmacokinetics of drugs. Within the solute carrier (SLC) family, various organic cation transporters (OCTs), organic anion transporters (OATs), and organic anion transporting poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cdf196b429471c6f97493332346d44
https://doi.org/10.1016/j.ab.2007.04.038
https://doi.org/10.1016/j.ab.2007.04.038
Autor:
Peer B. Jacobson, Lars Öhman, Birgitta Gelius, Marlena Grynfarb, Annika Goos-Nilsson, Richards Steven J, Masha Kalmanovich, Steven Fung, Thomas W. von Geldern, Denise Wilcox, Marie K. Österlund, Phong Nguyen, Jiahong Wang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:6086-6090
A series of potent steroidal glucocorticoid receptor antagonists has been discovered. After conjugation to cholic acid, the compounds retained an affinity for GR in vitro and had modest in vivo efficacy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec174e400bfc6de41f692b71623b9dd
https://doi.org/10.1016/j.bmcl.2006.08.133
https://doi.org/10.1016/j.bmcl.2006.08.133
Publikováno v:
Journal of Cell Science. 116:4521-4532
In the cell nucleus, precursors to mRNA, pre-mRNAs, associate with a large number of proteins and are processed to mRNA-protein complexes, mRNPs. The mRNPs are then exported to the cytoplasm and the mRNAs are translated into proteins. The mRNAs conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1342b3f623482af85acf2bd7dcd70d6
https://doi.org/10.1242/jcs.00766
https://doi.org/10.1242/jcs.00766
Publikováno v:
The EMBO Journal. 20:2802-2811
The mouse mammary tumor virus (MMTV) promoter is induced by glucocorticoid hormone via the glucocorticoid receptor (GR). The hormone-triggered effects on MMTV transcription and chromatin structure were studied in Xenopus oocytes. We previously showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7939cf9fef8fee6b9622962c40f03f11
https://doi.org/10.1093/emboj/20.11.2802
https://doi.org/10.1093/emboj/20.11.2802
Autor:
Örjan Wrange, Birgitta Gelius
Publikováno v:
Experimental Cell Research. 265:319-328
Oocytes from Xenopus laevis have provided a model system for studying the dynamic changes that occur in chromatin during gene activation. We have reconstituted glucocorticoid receptor (GR) induced transcription from the mouse mammary tumor virus (MMT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf8dd8fe2168eb2e86ef39d72fddaa1
https://doi.org/10.1006/excr.2001.5184
https://doi.org/10.1006/excr.2001.5184
Publikováno v:
European Journal of Biochemistry. 262:426-434
The yeast SWI2/SNF2 protein is a component of a large protein complex which is involved in the remodelling of chromatin during transcriptional activation. Several homologous complexes have been found in Drosophila and mammals. We have examined the ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eafca03e1e4d9192d06366f72a6fd020
https://doi.org/10.1046/j.1432-1327.1999.00379.x
https://doi.org/10.1046/j.1432-1327.1999.00379.x
Publikováno v:
The EMBO journal. 19(5)
The mouse mammary tumor virus (MMTV) promoter is induced by glucocorticoid hormone. A robust hormone- and receptor-dependent activation could be reproduced in Xenopus laevis oocytes. The homogeneous response in this system allowed a detailed analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b0b1c8cdd4c2832cc3252149ed1ea9
https://pubmed.ncbi.nlm.nih.gov/10698943
https://pubmed.ncbi.nlm.nih.gov/10698943