Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Birgitt Fischer"'
Autor:
Markus Haake, Beatrice Haack, Tina Schäfer, Patrick N. Harter, Greta Mattavelli, Patrick Eiring, Neha Vashist, Florian Wedekink, Sabrina Genssler, Birgitt Fischer, Julia Dahlhoff, Fatemeh Mokhtari, Anastasia Kuzkina, Marij J. P. Welters, Tamara M. Benz, Lena Sorger, Vincent Thiemann, Giovanni Almanzar, Martina Selle, Klara Thein, Jacob Späth, Maria Cecilia Gonzalez, Carmen Reitinger, Andrea Ipsen-Escobedo, Kilian Wistuba-Hamprecht, Kristin Eichler, Katharina Filipski, Pia S. Zeiner, Rudi Beschorner, Renske Goedemans, Falk Hagen Gogolla, Hubert Hackl, Rogier W. Rooswinkel, Alexander Thiem, Paula Romer Roche, Hemant Joshi, Dirk Pühringer, Achim Wöckel, Joachim E. Diessner, Manfred Rüdiger, Eugen Leo, Phil F. Cheng, Mitchell P. Levesque, Matthias Goebeler, Markus Sauer, Falk Nimmerjahn, Christine Schuberth-Wagner, Stefanie von Felten, Michel Mittelbronn, Matthias Mehling, Andreas Beilhack, Sjoerd H. van der Burg, Angela Riedel, Benjamin Weide, Reinhard Dummer, Jörg Wischhusen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Immune checkpoint blockade therapy is beneficial and even curative for some cancer patients. However, the majority don’t respond to immune therapy. Across different tumor types, pre-existing T cell infiltrates predict response to checkpoin
Externí odkaz:
https://doaj.org/article/5207814fce1e426b9e431dafa4d554e4
Autor:
Sabrina Genßler, Eugen Leo, Christine Schuberth-Wagner, Markus Haake, Neha Vashist, Beatrice Haack, Birgitt Fischer, Kristin Eichler, Matthias Kist, Joerg Wischhusen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/27a514e056894717a9a56526816cca58
Autor:
Markus Haake, Beatrice Haack, Sabrina Genßler, Julia Weigandt, Marlene Auer, Vincent Thiemann, Wahid M. Haq, Melanie Haag, Florian Wedekink, Birgitt Fischer, Kathrin Klar, Matthias Wölfl, Christine Schuberth-Wagner, Jorg Wischhusen
Publikováno v:
Cancer Research. 82:6118-6118
Background: Growth and differentiation factor 15 (GDF-15), a divergent member of the TGF-β protein superfamily, shows low physiological baseline expression. GDF-15 is, however, strongly upregulated during pregnancy. It is further induced in stressed
Autor:
Kilian Wistuba-Hamprecht, Eugen Leo, Mitchell P. Levesque, Tina Schäfer, Sabrina Genßler, Markus Haake, Reinhard Dummer, Birgitt Fischer, Jörg Wischhusen, Neha Vashist, Falk Nimmerjahn, Phil F. Cheng, Christine Schuberth-Wagner, Alexander Martens, Beatrice Haack, Kathrin Klar, Benjamin Weide, Michel Mittelbronn, Florian Wedekink, Patrick N. Harter
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A597-A597
BackgroundImmune checkpoint blockade (ICB) can achieve durable responses in a subgroup of patients with metastatic cancer, only. Poor immune effector cell infiltration into the tumor microenvironment is a major obstacle to successful therapy. Growth
Autor:
Eugen Leo, Neha Vashist, Markus Haake, Jörg Wischhusen, Paula S. Römer, Sabrina Genssler, Falk Nimmerjahn, Jessica Kammer, Birgitt Fischer, Kristin H. Eichler, Manfred Rudiger, Christine Schuberth-Wagner
Publikováno v:
Cancer Research. 80:5597-5597
Background: Growth and differentiation factor 15 (GDF-15) is a remote member of the TGF-β protein family with low to absent expression in healthy tissue. During pregnancy GDF-15 is secreted in high amounts by placenta contributing to feto-maternal t
Autor:
Ahmed Adel Seida, Stefan Heuer, Jenny Strohschein, Itsaso Montalbán del Barrio, Markus Junker, Jörg Wischhusen, Birgitt Fischer, Hermann Kneitz, Monika Ossadnik, Doris Kloor, Sebastian Häusler, Jörg B. Engel, Arnd Honig, Karl-Norbert Klotz, Mathias Krockenberger, Evi Horn, P. Anoop Chandran, Johannes Dietl
Publikováno v:
Cancer immunology, immunotherapy : CII. 60(10)
The ectonucleotidases CD39 and CD73 degrade immune stimulatory ATP to adenosine that inhibits T and NK cell responses via the A(2A) adenosine receptor (ADORA2A). This mechanism is used by regulatory T cells (T(reg)) that are associated with increased