Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Birgit Wendel"'
Autor:
Wolfgang Maier, Birgit Wendel, Petra Franke, Dieter B. Wildenauer, Sibylle G. Schwab, Daniela Neef, Margret R. Hoehe, Michael Knapp
Publikováno v:
European Psychiatry. 18:18-22
Objective. –In a modified case–control association study we tested the assumption that two polymorphisms (A118G in exon 1 and IVS2+31 in intron 2) of the human μ-opioid receptor gene (OPRM1) confer susceptibility to opioid dependence.Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41b98d04a855f18c95cc3c144a17dc2
https://doi.org/10.1016/s0924-9338(02)00005-6
https://doi.org/10.1016/s0924-9338(02)00005-6
Autor:
Hans Rommelspacher, Margret R. Hoehe, Ulrich Finckh, Lutz G. Schmidt, Jan Horodnicki, Jerzy Samochowiec, Ewa Fiszer-Piosik, Birgit Wendel
Publikováno v:
Drug and Alcohol Dependence. 65:221-224
Due to the involvement of the endogenous cannabinoid system in brain reward mechanisms a silent polymorphism (1359G/A; Thr453Thr) in the single coding exon of the CB1 human cannabinoid receptor gene ( CNR1 ) was analysed in 121 severely affected Cauc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf9945d754b301cc643a51ec54b0b01
https://doi.org/10.1016/s0376-8716(01)00164-8
https://doi.org/10.1016/s0376-8716(01)00164-8
Autor:
Ute Wachtendorf, Udo B. Zacharzowsky, Birgit Wendel, Richard Reinhard, Hagen D. Schulte, Margret R. Hoehe, Hannelore Haase, Karl Josef Osterziel, Ingo Morano
Publikováno v:
Journal of Cellular Biochemistry. 79:566-575
The β-myosin heavy chain gene (MYH7) encodes the motor protein that drives myocardial contraction. It has been proven to be a disease gene for hypertrophic cardiomyopathy (HCM). We analyzed the DNA sequence variation of MYH7 (about 16 kb) of eight i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0f7c131cbd130fba15c8edbe75e4e8b
https://doi.org/10.1002/1097-4644(20001215)79:4<566::aid-jcb50>3.0.co
https://doi.org/10.1002/1097-4644(20001215)79:4<566::aid-jcb50>3.0.co
Autor:
Marc-Antoine Crocq, Ingrid Grunewald, S.J.W. Delbrück, Deborah J. Morris-Rosendahl, Birgit Wendel, W.H. Berrettini, Margret R. Hoehe, Thomas Sander
Publikováno v:
Cytogenetic and Genome Research. 79:214-220
Allelic variation of the human serotonin transporter gene (SLC6A4) has recently been shown to modulate anxiety-related traits. A tandemly repeated sequence in close proximity to the promoter was found to be represented by a long (L) and short (S) var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f748c098e307e0fca45084f34b5befbb
https://doi.org/10.1159/000134726
https://doi.org/10.1159/000134726
Autor:
Jerzy Samochowiec, Nicola Gscheidel, Hans Rommelspacher, Birgit Wendel, Margret R. Hoehe, Lutz G. Schmidt, Michael N. Smolka, Thomas Sander
Publikováno v:
Alcoholism: Clinical and Experimental Research. 22:2108-2110
Mu-Opioid receptor-mediated neurotransmission is involved in the reward, tolerance, and withdrawal effects of alcohol. The present association study tested the hypothesis that the common Asn40Asp substitution polymorphism in the N-terminal domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cecb36bdfdae0185ffe6300de9b24614
https://doi.org/10.1111/j.1530-0277.1998.tb05923.x
https://doi.org/10.1111/j.1530-0277.1998.tb05923.x
Autor:
Jean-Paul Macher, Pierre Chiaroni, Marc-Antoine Crocq, Nicolas Levy, Thomas Sander, Ingrid Grunewald, Margret R. Hoehe, Birgit Wendel, Deborah J. Morris-Rosendahl
Publikováno v:
American Journal of Medical Genetics. 81:1-3
In a population-based association study, we tested the hypothesis that allelic variants of the human serotonin transporter (5-HTT) gene confer susceptibility to mood disorders. Both a biallelic repeat polymorphism in the 5′ promotor region that dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1f1506f8730e9024b36711e6a88567
https://doi.org/10.1002/(sici)1096-8628(19980207)81:1<1::aid-ajmg1>3.0.co
https://doi.org/10.1002/(sici)1096-8628(19980207)81:1<1::aid-ajmg1>3.0.co
Autor:
Klaus Rohde, Birgit Wendel, Karla Köpke, George M. Church, Kenneth K. Kidd, Christina Flachmeier, Margret R. Hoehe, Wade H. Berrettini
Publikováno v:
Human molecular genetics. 9(19)
To analyze candidate genes and establish complex genotype-phenotype relationships against a background of high natural genome sequence variability, we have developed approaches to (i) compare candidate gene sequence information in multiple individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40aab35137156feeac5df51720f8c7b
https://pubmed.ncbi.nlm.nih.gov/11092766
https://pubmed.ncbi.nlm.nih.gov/11092766
Publikováno v:
Epilepsy research. 39(1)
Pharmacological and autoradiological studies suggest that mu-opioid receptor (OPRM) mediated neurotransmission is involved in the generation of absence seizures. Mutation screening of the human OPRM gene identified a common amino acid substitution po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5118fe6dede7008a083b83a1680a26
https://pubmed.ncbi.nlm.nih.gov/10690754
https://pubmed.ncbi.nlm.nih.gov/10690754
Autor:
Hans Rommelspacher, Lutz G. Schmidt, Michael N. Smolka, Birgit Wendel, Nicola Gscheidel, Jerzy Samochowiec, Margret R. Hoehe, Thomas Sander
Publikováno v:
Psychoneuroendocrinology. 24(6)
Object: The endogenous opioid system plays an important role in the reinforcing properties of alcohol by an interconnected activation of the mesolimbic dopamine system. The Asn40Asp substitution polymorphism of the human μ-opioid-receptor (OPRM) inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551c5d9b6356d1aeb25d8df9b17d5140
https://pubmed.ncbi.nlm.nih.gov/10399772
https://pubmed.ncbi.nlm.nih.gov/10399772
Autor:
Margret R. Hoehe, Birgit Wendel
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 76(7)
The human mu opioid receptor (hMOR) interacts with endogenous and exogenous ligands to mediate its characteristic effects, reward, dependence, and analgesia. Specifically binding morphine, it represents the target of the most valuable pain killer in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcfbb4c9c77d5e686585820edaab03a
https://pubmed.ncbi.nlm.nih.gov/9660163
https://pubmed.ncbi.nlm.nih.gov/9660163