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of 6
pro vyhledávání: '"Birgit Watson"'
A Pharmacokinetic Dose-Optimization Study of Cabotegravir and Bictegravir in a Mouse Pregnancy Model
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1761 (2022)
Animal pregnancy models can be useful tools to study HIV antiretroviral safety and toxicity and to perform mechanistic studies that are not easily performed in humans. Utilization of clinically relevant dosing in these models improves the relevance o
Externí odkaz:
https://doaj.org/article/68d6932149ef422b859f477061bae2b5
Autor:
Marianne Harris, Bruce Ganase, Birgit Watson, P. Richard Harrigan, Julio S. G. Montaner, Mark W. Hull
Publikováno v:
AIDS Research and Therapy, Vol 14, Iss 1, Pp 1-9 (2017)
Abstract Background As a simplification strategy for treatment-experienced HIV-infected patients who have achieved virologic suppression on a multi-drug, multi-class antiretroviral regimen, the aim of this study was to evaluate the safety, efficacy,
Externí odkaz:
https://doaj.org/article/6b1b445205654b3c89269ea4baf838cd
Autor:
Chanson J. Brumme, Junine Toy, Kieran Atkinson, Paul Sereda, Rolando Barrios, Kathleen Auyeung, Katherine A Baynes, Katherine J. Lepik, Birgit Watson
Publikováno v:
Therapeutic drug monitoring. 43(5)
Background In British Columbia, antiretrovirals are distributed at no cost to patients via a publicly funded program, using generic formulations if available. A generic efavirenz-emtricitabine-tenofovir DF (EFV-FTC-TDF) combination pill became availa
Autor:
Monica S. Guzman Lenis, Michelle Dennehy, Lena Serghides, P. Richard Harrigan, D. William Cameron, Eszter Papp, Smriti Kala, Jeremy Guijun Zhang, Birgit Watson
Publikováno v:
Antiviral Research. 159:45-54
Animal models can be useful tools for the study of HIV antiretroviral (ARV) safety/toxicity in pregnancy and the mechanisms that underlie ARV-associated adverse events. The utility and translatability of animal model-based ARV safety/toxicity data is
Autor:
Silvia Guillemi, Bruce Ganase, P. Richard Harrigan, Mark Hull, Birgit Watson, Wendy Zhang, Ramesh Saeedi, Marianne Harris
Publikováno v:
HIV Clinical Trials. 18:39-47
To assess safety and efficacy of a switch to unboosted atazanavir (ATV) among HIV-infected adults receiving ATV/ritonavir (r) and tenofovir disoproxil fumarate (TDF).HIV-infected adults with viral load (VL) 40 copies/mL at screening and 150 copies/mL
Autor:
Adriana Nohpal, P. Richard Harrigan, Robert S. Hogg, Rolando Barrios, Birgit Watson, Julio S. G. Montaner, Rachel A. McGovern, Junine Toy, Benita Yip, David M. Moore, Linda Akagi, Katherine J. Lepik, Erin Ding
Publikováno v:
Antiviral therapy. 20(7)
Background Nevirapine 400 mg extended release tablets (nevirapine-XR) are a once-daily alternative to nevirapine 200 mg immediate release tablets (nevirapine-IR). Study objectives were to describe the effectiveness and tolerability of nevirapine-XR i