Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Birgit Strobl"'
Autor:
Torben Redmer, Martin Raigel, Christina Sternberg, Roman Ziegler, Clara Probst, Desiree Lindner, Astrid Aufinger, Tanja Limberger, Karolina Trachtova, Petra Kodajova, Sandra Högler, Michaela Schlederer, Stefan Stoiber, Monika Oberhuber, Marco Bolis, Heidi A. Neubauer, Sara Miranda, Martina Tomberger, Nora S. Harbusch, Ines Garces de los Fayos Alonso, Felix Sternberg, Richard Moriggl, Jean-Philippe Theurillat, Boris Tichy, Vojtech Bystry, Jenny L. Persson, Stephan Mathas, Fritz Aberger, Birgit Strobl, Sarka Pospisilova, Olaf Merkel, Gerda Egger, Sabine Lagger, Lukas Kenner
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background Prostate cancer develops through malignant transformation of the prostate epithelium in a stepwise, mutation-driven process. Although activator protein-1 transcription factors such as JUN have been implicated as potential oncogeni
Externí odkaz:
https://doaj.org/article/adefb22c8cb94d6696ce31c1da5a32f5
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/70e57a358c1b48eabb5db23065e9df74
Autor:
Joern Pezoldt, Carolin Wiechers, Florian Erhard, Ulfert Rand, Tanja Bulat, Michael Beckstette, Andrea Brendolan, Jochen Huehn, Ulrich Kalinke, Mathias Mueller, Birgit Strobl, Bart Deplancke, Luka Čičin-Šain, Katarzyna M. Sitnik
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Joern Pezoldt et al. analyze mouse spleen fibroblasts using single cell RNA sequencing, revealing 11 distinct clusters of fibroblastic cells or subtypes. Their results collectively provide further insight into the transcriptional identities of spleni
Externí odkaz:
https://doaj.org/article/a39bfb883b614159a6fc0d605a03133d
Autor:
Stefan Moritsch, Bernadette Mödl, Irene Scharf, Lukas Janker, Daniela Zwolanek, Gerald Timelthaler, Emilio Casanova, Maria Sibilia, Thomas Mohr, Lukas Kenner, Dietmar Herndler-Brandstetter, Christopher Gerner, Mathias Müller, Birgit Strobl, Robert Eferl
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Janus kinase Tyk2 is implicated in cancer immune surveillance, but its role in solid tumors is not well defined. We used Tyk2 knockout mice (Tyk2Δ/Δ) and mice with conditional deletion of Tyk2 in hematopoietic (Tyk2ΔHem) or intestinal epithelial c
Externí odkaz:
https://doaj.org/article/ec4f1b9c22f84cf89d8018da851833f7
Autor:
Julian Roewe, Georgios Stavrides, Marcel Strueve, Arjun Sharma, Federico Marini, Amrit Mann, Stephanie A. Smith, Ziya Kaya, Birgit Strobl, Mathias Mueller, Christoph Reinhardt, James H. Morrissey, Markus Bosmann
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Production of polyphosphate polymers is a ubiquitous trait of bacteria. Here, the authors investigate the role of bacterial long polyphosphates in host immune suppression and show that long polyphosphates produced by E. coli inhibit LPS-mediated infl
Externí odkaz:
https://doaj.org/article/981bd424c2f4496e8c311fc4f1a08f66
Autor:
Katharina Woess, Sabine Macho-Maschler, Dorette S. van Ingen Schenau, Miriam Butler, Caroline Lassnig, Daniel Valcanover, Andrea Poelzl, Katrin Meissl, Barbara Maurer, Tania Brandstoetter, Claus Vogl, Anna Koren, Stefan Kubicek, Anna Orlova, Richard Moriggl, Birgit Strobl, Veronika Sexl, Frank N. van Leeuwen, Roland P. Kuiper, Mathias Mueller
Publikováno v:
Haematologica, Vol 108, Iss 4 (2022)
Tyrosine kinase 2 (TYK2) is a member of the Janus kinase/signal transducer and activator of transcription pathway, which is central in cytokine signaling. Previously, germline TYK2 mutations have been described in two patients developing de novo T-ce
Externí odkaz:
https://doaj.org/article/16495fc0f1644407926d2399569c73ec
Autor:
Jan-Hendrik Schroeder, Luke B. Roberts, Katrin Meissl, Jonathan W. Lo, Dominika Hromadová, Kelly Hayes, Tomasz Zabinski, Emily Read, Catarina Moreira Heliodoro, Rita Reis, Jane K. Howard, Richard K. Grencis, Joana F. Neves, Birgit Strobl, Graham M. Lord
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Innate lymphoid cells (ILC) play a significant role in the intestinal immune response and T-bet+ CD127+ group 1 cells (ILC1) have been linked to the pathogenesis of human inflammatory bowel disease (IBD). However, the functional importance of ILC1 in
Externí odkaz:
https://doaj.org/article/5e18d42e0aa843848e7f5977f4051c1e
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Spondyloarthritis (SpA) is a family of inflammatory arthritic diseases, which includes the prototypes of psoriatic arthritis and ankylosing spondylitis. SpA is commonly associated with systemic inflammatory diseases, such as psoriasis and inflammator
Externí odkaz:
https://doaj.org/article/22ca145550bf40e8a4524ba0ca06a197
Autor:
Martin L Watzenboeck, Barbara Drobits, Sophie Zahalka, Anna-Dorothea Gorki, Asma Farhat, Federica Quattrone, Anastasiya Hladik, Karin Lakovits, Gabriel M Richard, Therese Lederer, Birgit Strobl, Gijs A Versteeg, Louis Boon, Philipp Starkl, Sylvia Knapp
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009487 (2021)
Lipocalin 2 (LCN2) is a secreted glycoprotein with roles in multiple biological processes. It contributes to host defense by interference with bacterial iron uptake and exerts immunomodulatory functions in various diseases. Here, we aimed to characte
Externí odkaz:
https://doaj.org/article/350841de659e460bb7aad2175ab5017b
Autor:
Jan-Hendrik Schroeder, Katrin Meissl, Dominika Hromadová, Jonathan W. Lo, Joana F. Neves, Jane K. Howard, Helena Helmby, Nick Powell, Birgit Strobl, Graham M. Lord
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Innate lymphoid cells (ILC) play a significant immunological role at mucosal surfaces such as the intestine. T-bet-expressing group 1 innate lymphoid cells (ILC1) are believed to play a substantial role in inflammatory bowel disease (IBD). However, a
Externí odkaz:
https://doaj.org/article/ba9f9bb4005040f781058400f748fa39